Search Results for: Non-small cell lung cancer

October 30, 2020October 30, 2020

Effect of cyclo-oxygenase inhibitor use during checkpoint blockade immunotherapy in patients with metastatic melanoma and non-small cell lung cancer.

Melanoma Literature

Publication date: Oct 01, 2020 Immune checkpoint inhibitors (ICIs) improve survival outcomes in metastatic melanoma and non-small cell lung cancer (NSCLC). Preclinical evidence suggests that overexpression of cyclo-oxygenase-2 (COX2) in ... Read more

October 22, 2020October 22, 2020

An antibody-drug conjugate targeting a GSTA glycosite-signature epitope of MUC1 expressed by non-small cell lung cancer.

Melanoma Literature

Publication date: Oct 20, 2020 Antibodies targeting aberrantly glycosylated proteins are ineffective in treating cancer. Antibody-drug conjugates have emerged as effective alternatives, facilitating tumor-specific drug delivery. Previous studies have assessed ... Read more

September 15, 2020September 15, 2020

Response rate and local recurrence after concurrent immune checkpoint therapy and radiotherapy for non-small cell lung cancer and melanoma brain metastases.

Melanoma Literature

Publication date: Sep 14, 2020 Prior literature has suggested synergy between immune checkpoint therapy (ICT) and radiotherapy (RT) for the treatment of brain metastases (BrM), but to the authors’ knowledge ... Read more

August 6, 2020August 6, 2020

Unravelling the Role of miR-20b-5p, CCNB1, HMGA2 and E2F7 in Development and Progression of Non-Small Cell Lung Cancer (NSCLC).

Precision Medicine Literature

Publication date: Aug 01, 2020 Lung cancer is a prime cause of worldwide cancer deaths, with non-small cell lung cancer (NSCLC) as a frequent subtype. Surgical resection, chemotherapy are the ... Read more

August 1, 2020August 1, 2020

Peripheral cytokines are not influenced by the type of surgical approach for non-small cell lung cancer by four weeks postoperatively.

Melanoma Literature

Publication date: Aug 01, 2020 The influence of surgical approach on systemic inflammatory response and the subsequent oncologic impact for non-small cell lung cancer is debated. We aimed to measure ... Read more

July 31, 2020July 31, 2020

Precision Medicine in Non-Small Cell Lung Cancer: Current Applications and Future Directions.

Precision Medicine Literature

Publication date: Jul 27, 2020 Advances in biomarkers, targeted therapies, and immuno-oncology have transformed the clinical management of patients with advanced NSCLC. For oncogene-driven tumors, there are highly effective targeted ... Read more

July 7, 2020July 7, 2020

Value of Precision Medicine in Advanced Non-Small Cell Lung Cancer: Real-World Outcomes Associated With the Use of Companion Diagnostics.

Precision Medicine Literature

Publication date: Jul 06, 2020 Companion diagnostic (CDx) testing for patients with advanced non-small cell lung cancer (aNSCLC) identifies patients more likely to benefit from biomarker-driven treatments. Patients with non-squamous ... Read more

July 2, 2020July 2, 2020

Costs of in-house genomic profiling and implications for economic evaluation: A case example of non-small cell lung cancer (NSCLC).

Precision Medicine Literature

Publication date: Jun 28, 2020 OBJECTIVES: Genomic profiling in oncology is vital for determining eligible patients for mutation-specific targeted therapies. Use of commercial genomic testing has the potential to improve ... Read more

November 1, 2020November 1, 2020

Clinical and Economic Value of Genetic Sequencing for Personalized Therapy in Non-small-cell Lung Cancer.

Precision Medicine Literature

Publication date: Nov 01, 2020 Two recent studies examining the clinical and economic value of next-generation sequencing (NGS)-based diagnostic testing (multi-gene panel examining ? 30 genes) for non-small-cell lung cancer ... Read more

August 19, 2020August 19, 2020

Radiomics in predicting treatment response in non-small-cell lung cancer: current status, challenges and future perspectives.

Precision Medicine Literature

Publication date: Aug 18, 2020 Radiomics is the extraction of quantitative data from medical imaging, which has the potential to characterise tumour phenotype. The radiomics approach has the capacity to ... Read more