Search Results for: Oxidative Stress

December 6, 2019December 6, 2019

A novel oxindole-curcumin hybrid compound for anti-oxidative stress and neuroprotection.

Publication date: Dec 04, 2019 Oxidative stress plays an important role in the pathogenesis of Parkinson’s disease and other neurodegenerative disorders. The oxindole compound GIF-2165X-G1 is a hybrid molecule composed ... Read more

December 6, 2019December 6, 2019

Interplay between MicroRNAs and Oxidative Stress in Neurodegenerative Diseases.

Huntington's Disease Literature

Publication date: Nov 30, 2019 MicroRNAs are post-transcriptional regulators of gene expression, crucial for neuronal differentiation, survival, and activity. Age-related dysregulation of microRNA biogenesis increases neuronal vulnerability to cellular stress ... Read more

November 30, 2019November 30, 2019

Pathophysiology and Therapeutic Perspectives of Oxidative Stress and Neurodegenerative Diseases: A Narrative Review.

Huntington's Disease Literature

Publication date: Nov 28, 2019 Neurodegeneration is the term describing the death of neurons both in the central nervous system and periphery. When affecting the central nervous system, it is ... Read more

November 16, 2019November 16, 2019

Supramolecular Insights into Domino Effects of Ag@ZnO-induced Oxidative Stress in Melanoma Cancer Cells.

Melanoma Literature

Publication date: Nov 15, 2019 Recent studies suggest that cancer cell death accompanied by organelle dysfunction might be a promising approach for cancer therapy. The Golgi apparatus has a key ... Read more

September 29, 2019September 29, 2019

Effects of Sulfated Fucans from Laminaria hyperborea Regarding VEGF Secretion, Cell Viability, and Oxidative Stress and Correlation with Molecular Weight.

Melanoma Literature

Publication date: Sep 25, 2019 Sulfated fucans show interesting effects in the treatment of ocular diseases (e.g., age-related macular degeneration), depending on their chemical structure. Here, we compared three purified ... Read more

July 16, 2019July 16, 2019

Towards a comprehensive understanding of the contributions of mitochondrial dysfunction and oxidative stress in the pathogenesis and pathophysiology of Huntington’s disease.

Huntington's Disease Literature

Publication date: Jul 15, 2019 Huntington’s disease (HD) is a rare autosomal dominant disorder affecting the corticostriatal area of the brain. HD is driven by elongated cytosine-adenine-guanine (CAG) repeat (36 ... Read more

June 27, 2019June 27, 2019

The effects of probiotic Saccharomyces boulardii on the mental health, quality of life, fatigue, pain, and indices of inflammation and oxidative stress in patients with multiple sclerosis: study protocol for a double-blind randomized controlled clinical trial.

Multiple Sclerosis Literature

Publication date: Jun 24, 2019 The relationship between gut dysbiosis and inflammatory diseases including multiple sclerosis (MS) is presently recognized as an important health issue. It has been established that ... Read more

June 17, 2019June 17, 2019

Bullfrog oil (Rana catesbeiana Shaw) induces apoptosis, in A2058 human melanoma cells by mitochondrial dysfunction triggered by oxidative stress.

Melanoma Literature

Publication date: Jun 13, 2019 Bullfrog oil, an animal oil extracted from the adipose tissue of Rana catesbeiana Shaw, showed promising cytotoxic activity against melanoma cells and, therefore, has the ... Read more

May 24, 2019May 24, 2019

Studying the ShcD and ERK interaction under acute oxidative stress conditions in melanoma cells.

Melanoma Literature

Publication date: May 20, 2019 The newly identified melanoma-associated adaptor ShcD was found to translocate to the nucleus upon hydrogen peroxide treatment. Therefore, the aim of this study was to ... Read more

May 1, 2019May 1, 2019

Mitophagy links oxidative stress conditions and neurodegenerative diseases.

Huntington's Disease Literature

Publication date: May 01, 2019 Mitophagy is activated by a number of stimuli, including hypoxia, energy stress, and increased oxidative phosphorylation activity. Mitophagy is associated with oxidative stress conditions and ... Read more