Search Results for: Oxidative Stress

June 4, 2020June 4, 2020

Selegiline (L-Deprenyl) Mitigated Oxidative Stress, Cognitive Abnormalities, and Histopathological Change in Rats: Alternative Therapy in Transient Global Ischemia.

Publication date: Jun 01, 2020 Selegiline (L-deprenyl) is the major drug which is used in the treatment of Parkinson’s disease because of its neurotrophic and antiapoptotic properties. Previous studies suggested ... Read more

June 1, 2020June 1, 2020

Wnt2 overexpression protects against PINK1 mutant-induced mitochondrial dysfunction and oxidative stress.

Parkinson's Disease Literature

Publication date: Jun 01, 2020 The PTEN induced putative kinase 1 (PINK1) mutation is the second most common cause of autosomal recessive adolescent Parkinson’s disease (PD). Furthermore, mitochondrial disorders and ... Read more

June 1, 2020June 1, 2020

Strengthening the Immune System and Reducing Inflammation and Oxidative Stress through Diet and Nutrition: Considerations during the COVID-19 Crisis.

Coronavirus Literature

Publication date: May 27, 2020 The coronavirus-disease 2019 (COVID-19) was announced as a global pandemic by the World Health Organization. Challenges arise concerning how to optimally support the immune system ... Read more

May 30, 2020May 30, 2020

The selenocompound 1-methyl-3-(phenylselanyl)-1H-indole attenuates depression-like behavior, oxidative stress, and neuroinflammation in streptozotocin-treated mice.

Major Depressive Disorder Literature

Publication date: May 26, 2020 Major depressive disorder (MDD) is a chronic mental illness affecting a wide range of people worldwide. The pathophysiology of MDD is not completely elucidated, but ... Read more

May 29, 2020May 29, 2020

Relevance of oxidative stress and inflammation in frailty based on human studies and mouse models.

Multiple Sclerosis Literature

Publication date: May 27, 2020 Frailty represents a state of vulnerability and increases the risk of negative health outcomes, which is becoming an important public health problem. Over recent years, ... Read more

May 25, 2020May 25, 2020

Assessment of oxidative stress in autism spectrum disorder using reactive oxygen metabolites and biological antioxidant potential.

Autism Literature

Publication date: Sep 20, 2019 There are several studies on oxidative stress of Autism Spectrum Disorder (ASD), but in these cases there is no study to measure oxidative stress and ... Read more

May 22, 2020May 22, 2020

Natural product corynoline suppresses melanoma cell growth through inducing oxidative stress.

Melanoma Literature

Publication date: May 19, 2020 Natural product corynoline is a unique isoquinoline alkaloid extracted from traditional Chinese medicine Corydalis bungeana Turcz, whereas its anticancer properties have not been investigated. In ... Read more

May 21, 2020May 21, 2020

Melanoma in the liver: oxidative stress and the mechanisms of metastatic cell survival.

Melanoma Literature

Publication date: May 16, 2020 Metastatic melanoma is a fatal disease with a rapid systemic dissemination. The most frequent target sites are the liver, bone, and brain. Melanoma metastases represent ... Read more

May 11, 2020May 11, 2020

Oxidative Stress and Immune System Dysfunction in Autism Spectrum Disorders.

Autism Literature

Publication date: May 06, 2020 Autism Spectrum Disorders (ASDs) represent a group of neurodevelopmental disorders associated with social and behavioral impairments. Although dysfunctions in several signaling pathways have been associated ... Read more

May 7, 2020May 7, 2020

Oxidative Stress and Genotoxicity in Melanoma Induction: Impact on Repair Rather Than Formation of DNA Damage?

Melanoma Literature

Publication date: May 04, 2020 Keratinocytes and melanocytes, two cutaneous cell types located within the epidermis, are the origin of most skin cancers, namely carcinomas and melanomas. These two types ... Read more