Publication date: May 19, 2025 Concepts Keywords Clinical Associated Disease Clinical Lrrk2 Disease Parkinson Disord Synucleinopathy Lrrk2 Mov Parkinson Synucleinopathy Semantics Type Source Name disease MESH Parkinson’s Disease disease MESH ... Read more

Publication date: May 20, 2025 Mutations in Leucine-Rich Repeat protein Kinase 2 (LRRK2) are associated with Parkinson’s disease (PD) and Crohn’s disease (CD), but the regulation of LRRK2 during inflammation ... Read more

Publication date: May 20, 2025 Microglia-mediated neuroinflammation plays an important role in the pathogenesis of Parkinson’s disease (PD). Studies have shown that butylphthalide (3-n-butylphthalide or NBP) can play an anti-inflammatory ... Read more

Publication date: May 20, 2025 With the rapid development of digital biomarkers in Parkinson disease (PD) research, it has become increasingly important to explore the current research trends and key ... Read more

Publication date: May 20, 2025 Cognitive impairment in Parkinson’s disease (PD) is a widespread and rapidly progressive feature that impacts prognosis. Although TREM2 has been implicated in neuroprotection across various ... Read more

Publication date: May 20, 2025 Despite universal access to healthcare to eligible people of all ethnic backgrounds in the NHS, disparity in healthcare provision exists. Parkinson’s disease (PD) is a ... Read more

Publication date: May 20, 2025 Parkinson’s disease (PD), although widely heterogeneous and manifesting with numerous motor and non-motor symptoms, presents clinically as a single entity worldwide. Its genetic causes are ... Read more

Publication date: May 20, 2025 Diagnosing Atypical Parkinsonian Syndromes (APS) may be challenging due to overlapping clinical features of Parkinson’s disease (PD), and the lack of pathognomonic diagnostic tests. Fluid ... Read more

Publication date: May 20, 2025 BackgroundCognitive impairment and dementia are common findings in patients with Parkinson’s disease (PD). However, the long-term effects of subthalamic deep brain stimulation (STN-DBS) on cognition ... Read more

Publication date: May 20, 2025 BackgroundAnxiety often exacerbates freezing of gait (FOG) in people with Parkinson’s (PwP). Anxiety-related attentional processes and associated processing inefficiencies, like conscious movement processing (CMP) and ... Read more