Search Results for: Pentaerythritol tetranitrate

April 21, 2025

SLIRP amplifies antiviral signaling via positive feedback regulation and contributes to autoimmune diseases.

Melanoma Literature

Publication date: Apr 19, 2025 Abnormal innate immune response is a prominent feature underlying autoimmune diseases. One emerging factor driving dysregulated immune activation is cytosolic mitochondrial double-stranded RNAs (mt-dsRNAs). However, ... Read more

April 21, 2025

Inhibition of tRF- 02514 in Extracellular Vesicles Preserves Microglia Pyroptosis and Protects Against Parkinson’s Disease.

Parkinson's Disease Literature

Publication date: Apr 21, 2025 Extracellular vesicles (EVs), ubiquitous in peripheral blood and bodily fluids, are important regulators of neuronal communication, facilitating the intercellular transfer of bioactive molecules crucial for ... Read more

April 21, 2025

Sickness absence among blue-collar workers in the retail and wholesale industry during the COVID-19 pandemic; a longitudinal cohort study.

Coronavirus Literature

Publication date: Apr 20, 2025 Sickness absence (SA) changed in various occupations during the COVID-19 pandemic. The aim was to investigate the prevalence of all-cause sickness absence (SA) during the ... Read more

April 21, 2025

Utilizing artificial intelligence to predict and analyze socioeconomic, environmental, and healthcare factors driving tuberculosis globally.

Tuberculosis Literature

Publication date: Apr 19, 2025 Tuberculosis (TB) is a major global health issue, contributing significantly to mortality and morbidity rates worldwide. Socioeconomic, environmental, and healthcare factors significantly impact TB trends. ... Read more

April 21, 2025April 21, 2025

The experience and perception of wearable devices in Parkinson’s disease patients: a systematic review and meta-synthesis of qualitative studies.

Parkinson's Disease Literature

Publication date: Apr 19, 2025 Parkinson’s disease (PD) is the fastest-growing neurodegenerative disorder, affecting over 8. 5 million people worldwide, with symptoms that severely impact patients’ quality of life. While ... Read more

April 21, 2025

Contralateral Prefrontal and Network Engagement during Left DLPFC 10 Hz rTMS: An Interleaved TMS-fMRI Study in Healthy Adults

Major Depressive Disorder News

Publication date: Apr 18, 2025 Background: High-frequency repetitive transcranial magnetic stimulation (rTMS) over the left dorsolateral prefrontal cortex (DLPFC) serves as an effective treatment for major depression and other psychiatric ... Read more

April 21, 2025

Chikungunya virus virus-like particle vaccine safety and immunogenicity in adults older than 65 years: a phase 3, randomised, double-blind, placebo-controlled trial.

Chikungunya Literature

Publication date: Apr 19, 2025 Adults older than 65 years are at increased risk for atypical presentations of chikungunya disease, as well as for severe outcomes including death. In this ... Read more

April 20, 2025

Adjuvant dendritic cell-based immunotherapy in melanoma: insights into immune cell dynamics and clinical evidence from a phase II trial.

Melanoma Literature

Publication date: Apr 18, 2025 Dendritic cells (DCs) are the most efficient antigen-presenting cells and play a central role in the immune system, orchestrating immune response against tumors. We previously ... Read more

April 20, 2025April 20, 2025

Alignment-free viral sequence classification at scale.

Coronavirus Literature

Publication date: Apr 18, 2025 The rapid increase in nucleotide sequence data generated by next-generation sequencing (NGS) technologies demands efficient computational tools for sequence comparison. Alignment-free (AF) methods offer a ... Read more

April 20, 2025April 20, 2025

Detecting neuropsychiatric fluctuations in Parkinson’s Disease using patients’ own words: the potential of large language models.

Parkinson's Disease Literature

Publication date: Apr 18, 2025 Over the past decade, neuropsychiatric fluctuations in Parkinson’s disease (PD) have been increasingly recognized for their impact on patients’ quality of life. Speech, a complex ... Read more