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Versatile and sensitive dual-detection HPLC method for rapid quantification of apomorphine hydrochloride: application to ex vivo percutaneous permeation and deposition studies utilising novel transdermal pressure-sensitive adhesive patches.

Versatile and sensitive dual-detection HPLC method for rapid quantification of apomorphine hydrochloride: application to ex vivo percutaneous permeation and deposition studies utilising novel transdermal pressure-sensitive adhesive patches.

Parkinson's Disease Literature
Publication date: Jul 15, 2025 Conventional delivery of apomorphine hydrochloride (APO) for management of ‘OFF’ periods in Parkinson’s disease is limited to subcutaneous or sublingual delivery, and would substantially benefit ... Read more