Search Results for: Preprint

October 12, 2024October 12, 2024

Public understanding of preprints: How audiences make sense of unreviewed research in the news.

Publication date: Oct 11, 2024 News reporting of preprints became commonplace during the COVID-19 pandemic, yet the extent to which the public understands what preprints are is unclear. We sought ... Read more

October 12, 2024October 12, 2024

Public understanding of preprints: How audiences make sense of unreviewed research in the news.

Coronavirus Literature

October 14, 2024October 14, 2024

Unraveling the Associations Between Voice Pitch and Major Depressive Disorder: A Multisite Genetic Study

Major Depressive Disorder News

Publication date: Oct 12, 2024 Major depressive disorder (MDD) often goes undiagnosed due to the absence of clear biomarkers. We sought to identify voice biomarkers for MDD and separate biomarkers ... Read more

October 14, 2024October 14, 2024

Ventral Striatum is Preferentially Correlated with the Salience Network Including Regions in Dorsolateral Prefrontal Cortex

Major Depressive Disorder News

Publication date: Oct 12, 2024 The ventral striatum (VS) receives input from the cerebral cortex and is modulated by midbrain dopaminergic projections in support of processing reward and motivation. Here ... Read more

October 14, 2024October 14, 2024

Analyzing greedy vaccine allocation algorithms for metapopulation disease models

Coronavirus News

Publication date: Oct 12, 2024 As observed in the case of COVID-19, effective vaccines for an emerging pandemic tend to be in limited supply initially and must be allocated strategically. ... Read more

October 13, 2024October 13, 2024

Reprogrammed Human Lateral Ganglionic Eminence Precursors Generate Striatal Neurons and Restore Motor Function in a Rat Model of Huntington’s Disease.

Huntington's Disease News

Publication date: Oct 11, 2024 Background: Huntington’s disease (HD) is a genetic neurological disorder predominantly characterised by the progressive loss of GABAergic medium spiny neurons in the striatum resulting in ... Read more

October 13, 2024October 13, 2024

A Comprehensive App to Interpret and Visualize the Functional Analysis of KEGG Pathways and Gene Ontologies

Dr. Richard A. Blevins News, Informatics News

Publication date: Oct 11, 2024 This report explains how a comprehensive app designed for the interpretation and visualization of the functional analysis related to KEGG pathways and gene ontologies works, ... Read more

October 12, 2024October 12, 2024

Identification of targetable epigenetic vulnerabilities in uveal melanoma

Melanoma News

Publication date: Oct 10, 2024 Uveal melanoma (UM) is the most prevalent primary intraocular malignancy in adults, which preferentially metastasizes to the liver in approximately half of all cases. Metastatic ... Read more

October 12, 2024October 12, 2024

Mgat4b mediated selective N-glycosylation regulates melanocyte development and melanoma progression

Melanoma News

Publication date: Oct 10, 2024 Melanocyte development involves key pathways that are often recapitulated during melanoma initiation, highlighting the importance of understanding the regulators that control these early processes and ... Read more

October 12, 2024October 12, 2024

Dopamine and cortical iPSC-derived neurons with different Parkinsonian mutations show variation in lysosomal and mitochondrial dysfunction: implications for protein deposition versus selective cell loss

Parkinson's Disease News

Publication date: Oct 10, 2024 Background: Mutations causing Parkinson’s disease (PD) give diverse pathological phenotypes whose cellular correlates remain to be determined. For example, those with PRKN loss of function ... Read more