Search Results for: Promising

May 20, 2025May 20, 2025

WTAP is a promising diagnosis and treatment biomarker that inhibits the proliferation and invasion of melanoma cells.

Melanoma Literature

Publication date: May 20, 2025 Wilms’ tumour 1-associating protein (WTAP) is ubiquitously expressed in many tissues and plays an important role in physiological processes and tumour development. Here, we investigated ... Read more

May 20, 2025

Transforming Niclosamide through Nanotechnology: A Promising Approach for Long COVID Management.

Coronavirus Literature

Publication date: May 19, 2025 Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has infected over 770 million people worldwide. The long-term effects of COVID-19 ... Read more

May 16, 2025

Biomarker Mechanism for ALTO-300 in Precision Psychiatry Study Proves Promising in MDD Treatment, According to Amit Etkin, MD, PhD

Major Depressive Disorder News

Publication date: May 16, 2025 The drug targets melatonin receptors and blocks 5-HT2C serotonin receptors, leading to downstream dopamine enhancement. Alto Neuroscience Presents New Data at the Society of Biological ... Read more

May 15, 2025

Synthesis, Antimycobacterial Activity and Computational Insight of novel 1,4-Benzoxazin-2-one Derivatives as Promising Candidates Against Multidrug-Resistant M. tuberculosis.

Tuberculosis Literature

Publication date: May 14, 2025 To search for new antitubercular agents, we have designed, synthesized, and evaluated a series of 1,4-benzoxazinone-based compounds. These molecules showed potent antimycobacterial activity, with MIC ... Read more

May 9, 2025

Brain-derived extracellular vesicles: A promising avenue for Parkinson’s disease pathogenesis, diagnosis, and treatment.

Parkinson's Disease Literature

Publication date: Apr 29, 2025 The misfolding, aggregation, and deposition of alpha-synuclein into Lewy bodies are pivotal events that trigger pathological changes in Parkinson’s disease. Extracellular vesicles are nanosized lipidbilayer ... Read more

May 9, 2025

In Vivo Safety Assessment of AZT-derived Organochalcogen Compounds with Promising Antiviral Effects against SARS-Cov-2.

Coronavirus Literature

Publication date: May 07, 2025 Developing new COVID-19 antivirals requires understanding viral proteins, oxidative stress, and drug repositioning. Safety assessments of organochalcogen molecules derived from AZT in Caenorhabditis elegans offer ... Read more

May 2, 2025May 2, 2025

2-(Phenylamino)-7,8-dihydroquinazolin-5(6H)-one, a promising scaffold for MAO-B inhibitors with potential GSK3β targeting.

Parkinson's Disease Literature

Publication date: Jul 05, 2025 Neurodegenerative disorders, such as Parkinson’s disease and Alzheimer’s disease, constitute pathological conditions of great relevance on health span and quality of life. The identification of ... Read more

May 1, 2025

Encapsulation of Ferula-derived bioactive compounds in nanoparticles: A promising therapeutic route for cancers and infectious diseases.

Coronavirus Literature

Publication date: Apr 29, 2025 The biomedical sector is constantly searching for new drugs that efficiently improve human health and well-being with minimum side effects. Bio-inspired nanomedicine has emerged as ... Read more

May 1, 2025

Molecular dynamics simulation and docking studies reveals inhibition of NF-kB signaling as a promising therapeutic drug target for reduction in cytokines storms.

Coronavirus Literature

Publication date: Apr 30, 2025 Nuclear factor-kappa B (NF-kB) plays a crucial role in numerous cellular processes, such as inflammation, immunological responses to infection, cell division, apoptosis, and the development ... Read more

April 29, 2025

Early combined therapy for COVID-19 in immunocompromised patients: a promising approach against viral persistence and drug resistance.

Coronavirus Literature

Publication date: Apr 28, 2025 Immunocompromised (IC) patients face significant challenges in managing COVID-19 due to their heightened susceptibility to severe illness, persistent infections, and the potential development of drug ... Read more