Search Results for: Protein Domains

March 20, 2025March 20, 2025

Chemokines simultaneously bind SARS-CoV-2 nucleocapsid protein RNA-binding and dimerization domains.

Publication date: Mar 17, 2025 Viruses express chemokine (CHK)-binding proteins to interfere with the host CHK network and thereby modulate leukocyte migration. SARS-CoV-2 Nucleocapsid (N) protein binds a subset of ... Read more

March 6, 2025March 6, 2025

Changes in the motifs in the D0 and SD2 domains of the S protein drive the evolution of virulence in enteric coronavirus porcine epidemic diarrhea virus.

Coronavirus Literature

Publication date: Mar 04, 2025 Since 2010, highly virulent mutant GII subtype porcine epidemic diarrhea virus (PEDV) strains derived from GI subtype strains have caused significant economic losses in the ... Read more

March 6, 2025March 6, 2025

Changes in the motifs in the D0 and SD2 domains of the S protein drive the evolution of virulence in enteric coronavirus porcine epidemic diarrhea virus.

Coronavirus Literature

March 6, 2025March 6, 2025

Changes in the motifs in the D0 and SD2 domains of the S protein drive the evolution of virulence in enteric coronavirus porcine epidemic diarrhea virus.

Coronavirus Literature

February 20, 2025February 20, 2025

Gelsolin traps ribosomal protein SA (RPSA) within lipid nanodomains of the plasma membrane and modulates the level of protein synthesis in the submembranous region of human skin melanoma cells.

Melanoma Literature

Publication date: Mar 01, 2025 The connection between the F-actin and ribosome docking to the PM has been reported, but the exact mechanism has remained unclear. Previously, we discovered that ... Read more

March 20, 2025March 20, 2025

Distinct roles of SARS-CoV-2 N protein and NFP in host cell response modulation.

Coronavirus Literature

Publication date: Mar 17, 2025 The SARS-CoV-2 nucleocapsid (N) protein is crucial for viral replication and modulation of host cell responses. Here, we identify and characterize a novel N-fusion protein, ... Read more

March 20, 2025March 20, 2025

Mycobacterium tuberculosis CrgA Forms a Dimeric Structure with Its Transmembrane Domain Sandwiched between Cytoplasmic and Periplasmic β-Sheets, Enabling Multiple Interactions with Other Divisome Proteins.

Tuberculosis Literature

Publication date: Mar 19, 2025 CrgA is a key transmembrane (TM) protein in the cell division process of Mycobacterium tuberculosis (Mtb), the pathogen responsible for tuberculosis. While many of the ... Read more

March 17, 2025March 17, 2025

Structure and dynamics of Alpha B.1.1.7 SARS-CoV-2 S-protein in complex with Fab of neutralizing antibody REGN10987.

Coronavirus Literature

Publication date: Apr 01, 2025 One of the approaches for treatment of COVID-19 is a use of neutralizing antibodies (nAbs). The study of the mechanisms by which nAbs recognize different ... Read more

March 15, 2025March 15, 2025

Host Response Protein Biomarkers Indicative of Persistent Acute Kidney Injury in Critically Ill COVID-19 Patients.

Coronavirus Literature

Publication date: Mar 01, 2025 Sepsis-related host-response anomalies contribute to acute kidney injury (AKI) duration. Data on the host-response specific to COVID-19-associated AKI (COVID-AKI) in critically ill patients is limited. ... Read more

March 15, 2025March 15, 2025

Host Response Protein Biomarkers Indicative of Persistent Acute Kidney Injury in Critically Ill COVID-19 Patients.

Coronavirus Literature