Search Results for: Putamen

May 11, 2018May 11, 2018

Transcriptomic integration of DR and MOR signaling in the rat caudate putamen.

Opioids Literature

Publication date: May 09, 2018 Morphine binding to opioid receptors, mainly to μ opioid receptor (MOR), induces alterations in intracellular pathways essential to the initial development of addiction. The activation ... Read more

May 4, 2018May 4, 2018

Atrophy of the putamen at time of clinical motor onset in Huntington’s disease: a 6-year follow-up study.

Huntington's Disease Literature

Publication date: Sep 20, 2017 Striatal atrophy is detectable many years before the predicted onset of motor symptoms in premanifest Huntington’s disease (HD). However, the extent of these neurodegenerative changes ... Read more

July 22, 2019July 22, 2019

Beneficial effect of estrogen on nigrostriatal dopaminergic neurons in drug-naïve postmenopausal Parkinson’s disease.

Parkinson's Disease Literature

Publication date: Jul 19, 2019 This study aimed to investigate the potential beneficial effects of estrogen on nigrostriatal dopaminergic neuron degeneration in postmenopausal drug-nacEFve Parkinson’s disease (PD). Based on the ... Read more

July 18, 2019July 18, 2019

MR susceptibility contrast imaging using a 2D simultaneous multi-slice gradient-echo sequence at 7T.

Multiple Sclerosis Literature

Publication date: Mar 12, 2019 To develop a 7T simultaneous multi-slice (SMS) 2D gradient-echo sequence for susceptibility contrast imaging, and to compare its quality to 3D imaging. A frequency modulated ... Read more

July 6, 2019July 6, 2019

Structural neuroimaging differentiates vulnerability from disease manifestation in colombian families with Huntington’s disease.

Huntington's Disease Literature

Publication date: Jul 05, 2019 The volume of the striatal structures has been associated with disease progression in individuals with Huntington’s disease (HD) from North America, Europe, and Australia. However, ... Read more

July 3, 2019July 3, 2019

Clinicopathological differences between the motor onset and psychiatric onset of Huntington’s disease, focusing on the nucleus accumbens.

Huntington's Disease Literature

Publication date: Jul 02, 2019 Huntington’s disease (HD) is an autosomal-dominant neurodegenerative disorder characterized by the presence of chorea, psychiatric symptoms, and dementia. Although motor symptoms are thought to be ... Read more

June 8, 2019June 8, 2019

Diffusion tensor imaging of the normal-appearing deep gray matter in primary and secondary progressive multiple sclerosis.

Multiple Sclerosis Literature

Publication date: Jun 06, 2019 Despite strongly overlapping patterns of clinical and histopathologic findings in primary and secondary progressive multiple sclerosis, differences concerning motor symptoms, central nervous system inflammation, atrophy, ... Read more

June 5, 2019June 5, 2019

Neuroplasticity of the sensorimotor neural network associated with walking aid training in people with multiple sclerosis.

Multiple Sclerosis Literature

Publication date: Jun 01, 2019 The objective of this pilot study was to identify neural descriptors and correlates of participation in a multicomponent walking aid program, the Assistive Device Selection, ... Read more

May 29, 2019May 29, 2019

Longitudinal characterization of cognitive and motor deficits in an excitotoxic lesion model of striatal dysfunction in non-human primates.

Huntington's Disease Literature

Publication date: May 24, 2019 As research progresses in the understanding of the molecular and cellular mechanisms underlying neurodegenerative diseases like Huntington’s disease (HD) and expands towards preclinical work for ... Read more

May 14, 2019May 14, 2019

Deep grey matter involvement and altered sensory gating in multiple sclerosis.

Multiple Sclerosis Literature

Publication date: May 13, 2019 Somatosensory temporal discrimination threshold (STDT) is altered in multiple sclerosis (MS). In healthy subjects (HS), voluntary movement modulates the STDT through mechanisms of subcortical sensory ... Read more