Search Results for: ROS1

December 2, 2019December 2, 2019

RET fusions in solid tumors.

Melanoma Literature

Publication date: Dec 01, 2019 The RET proto-oncogene has been well-studied. RET is involved in many different physiological and developmental functions. When altered, RET mutations influence disease in a variety ... Read more

November 18, 2019November 18, 2019

How inflammation could link Parkinson’s, Crohn’s, and leprosy

Parkinson's Disease News

Publication date: Nov 18, 2019 Dr. Bojan Shutinoski, the first author of the study published in Science Translational Medicine at The Ottawa Hospital, explained to The Varsity that the gene ... Read more

November 16, 2019November 16, 2019

Supramolecular Insights into Domino Effects of Ag@ZnO-induced Oxidative Stress in Melanoma Cancer Cells.

Melanoma Literature

Publication date: Nov 15, 2019 Recent studies suggest that cancer cell death accompanied by organelle dysfunction might be a promising approach for cancer therapy. The Golgi apparatus has a key ... Read more

November 16, 2019

Caring for the Patient With Opioid Use Disorder in an Outpatient Setting: Overcoming the Barriers to Medication-Assisted Treatment

Opioids News

Publication date: Nov 12, 2019 Joshua D. Lee, MD, MSc, prepared opioid use disorder infographics for this CME activity titled “Caring for the Patient With Opioid Use Disorder in an ... Read more

November 15, 2019November 15, 2019

An integrative methodology based on protein-protein interaction networks for identification and functional annotation of disease-relevant genes applied to channelopathies.

Precision Medicine Literature

Publication date: Nov 12, 2019 Biologically data-driven networks have become powerful analytical tools that handle massive, heterogeneous datasets generated from biomedical fields. Protein-protein interaction networks can identify the most relevant ... Read more

November 15, 2019November 15, 2019

The translational network for metabolic disease – from protein interaction to disease co-occurrence.

Precision Medicine Literature

Publication date: Nov 13, 2019 The recent advances in human disease network have provided insights into establishing the relationships between the genotypes and phenotypes of diseases. In spite of the ... Read more

November 15, 2019November 15, 2019

Synthesis, biological evaluation and mechanism studies of C-23 modified 23-hydroxybetulinic acid derivatives as anticancer agents.

Melanoma Literature

Publication date: Nov 15, 2019 A series of C-23 modified 23-hydroxybetulinic acid (HBA) derivatives were synthesized and evaluated for their antiproliferative activity against a panel of cancer cell lines (A2780, ... Read more

November 12, 2019November 12, 2019

Cardiovascular Aging Contributes to Brain Aging

Parkinson's Disease News

Publication date: Nov 10, 2019 Cardiovascular aging can reduce that supply, whether through conditions such as heart failure, or the progressive loss of density in capillary networks that occurs throughout ... Read more

November 1, 2019November 1, 2019

A Randomized Controlled Trial of a Multicomponent Walking Aid Program for People With MS

Multiple Sclerosis News

Publication date: Oct 31, 2019 This is a randomized controlled trial of the Assistive Device Selection, Training, and Education Program (ADSTEP). ADSTEP is a training program of six weekly one-on-one ... Read more

October 30, 2019October 30, 2019

The hidden information in patient-reported outcomes and clinician-assessed outcomes: multiple sclerosis as a proof of concept of a machine learning approach.

Multiple Sclerosis Literature

Publication date: Oct 28, 2019 Machine learning (ML) applied to patient-reported (PROs) and clinical-assessed outcomes (CAOs) could favour a more predictive and personalized medicine. Our aim was to confirm the ... Read more