Search Results for: Randomized controlled trial

December 6, 2019December 6, 2019

Trajectory classes of opioid use among individuals in a randomized controlled trial comparing extended-release naltrexone and buprenorphine-naloxone.

Opioids Literature

Publication date: Dec 01, 2019 To advance our understanding of medication treatments for opioid use disorders (OUDs), identification of distinct subgroups and factors associated with differential treatment response is critical. ... Read more

November 17, 2019November 17, 2019

Efficacy of Cancer Immunotherapy: An Umbrella Review of Meta-analyses of Randomized Controlled Trials.

Melanoma Literature

Publication date: Nov 15, 2019 We conducted a systematic review for evidence of the clinical efficacy of cancer immunotherapies. We searched PubMed from inception to 14 February 2018 for meta-analyses ... Read more

November 8, 2019November 8, 2019

Traffic Lights Intervention Reduces Therapeutic Inertia: A Randomized Controlled Trial in Multiple Sclerosis Care.

Multiple Sclerosis Literature

Publication date: Feb 08, 2019 Background: Therapeutic inertia (TI) is a common phenomenon among physicians who care for patients with chronic conditions. We evaluated the efficacy of the traffic light ... Read more

November 1, 2019November 1, 2019

A Randomized Controlled Trial of a Multicomponent Walking Aid Program for People With MS

Multiple Sclerosis News

Publication date: Oct 31, 2019 This is a randomized controlled trial of the Assistive Device Selection, Training, and Education Program (ADSTEP). ADSTEP is a training program of six weekly one-on-one ... Read more

October 31, 2019October 31, 2019

Neuropsychological management of multiple sclerosis: evaluation of a supervised and customized cognitive rehabilitation program for self-used at home (SEPIA): protocol for a randomized controlled trial.

Multiple Sclerosis Literature

Publication date: Oct 29, 2019 Cognitive and mood disorders negatively impact daily life in patients with multiple sclerosis (MS). Pharmacological treatments did not demonstrate any effect on cognition compared with ... Read more

October 31, 2019October 31, 2019

Association of Bariatric Surgery With Skin Cancer Incidence in Adults With Obesity: A Nonrandomized Controlled Trial.

Melanoma Literature

Publication date: Oct 30, 2019 Obesity is a cancer risk factor, and bariatric surgery in patients with obesity is associated with reduced cancer risk. However, evidence of an association among ... Read more

October 18, 2019October 18, 2019

reSET-O RCT (Randomized Controlled Trial)

Opioids News

Publication date: Oct 17, 2019 This randomized controlled trial research study will be evaluating an app, reSET-O, owned by Pear Therapeutics, Inc., to evaluate treatment retention rates in individuals with ... Read more

October 10, 2019October 10, 2019

Personalized, Web-Based, Guided Self-Help for Patients With Medically Unexplained Symptoms in Primary Care: Protocol for a Randomized Controlled Trial.

Precision Medicine Literature

Publication date: Oct 08, 2019 Medically unexplained symptoms (MUS) constitute a major health problem because of their high prevalence, the suffering and disability they cause, and the associated medical costs. ... Read more

October 1, 2019October 1, 2019

Mindfulness-oriented recovery enhancement reduces opioid misuse risk via analgesic and positive psychological mechanisms: A randomized controlled trial.

Opioids Literature

Publication date: Oct 01, 2019 Despite the heightened urgency of the current prescription opioid crisis, few psychotherapies have been evaluated for chronic pain patients receiving long-term opioid analgesics. Current psychological ... Read more

October 1, 2019October 1, 2019

Additive Duloxetine for Cancer-Related Neuropathic Pain Nonresponsive or Intolerant to Opioid-Pregabalin Therapy: A Randomized Controlled Trial (JORTC-PAL08).

Opioids Literature

Publication date: Oct 01, 2019 Although opioids and pregabalin are widely used for cancer-related neuropathic pain (CNP), no clinical trials exist to determine which medications are effective when an opioid-pregabalin ... Read more