Search Results for: Rich

January 16, 2025January 16, 2025

Differential Gene Set Enrichment of Epithelial-Mesenchymal Transition Pathway in BRAF vs. NRAS Mutated Metastatic Melanoma.

Melanoma Literature

Publication date: Jan 15, 2025 This study investigates the differential activation of the epithelial-mesenchymal transition (EMT) pathway in metastatic melanoma, focusing on BRAF- and NRAS-mutated samples from The Cancer Genome ... Read more

January 16, 2025January 16, 2025

Human HKU1-reactive CD4 T cells are enriched for cytolytic potential that persists in older adults.

Coronavirus Literature

Publication date: Jan 15, 2025 The emergence of SARS-CoV-2 increased interest in cellular immunity established by infections with human coronaviruses (HCoVs). Using PBMC from a cohort of human subjects collected ... Read more

January 13, 2025January 13, 2025

Evaluation of Enrichment Approaches for the Study of the Viromes in Mollusk Species.

Coronavirus Literature

Publication date: Jan 12, 2025 Invasive alien species such as freshwater snails have significantly affected the food, environment, and the health of humans and animals, which have unfortunately received insufficient ... Read more

January 10, 2025January 10, 2025

Targeted Enrichment Sequencing Utilizing a Respiratory Pathogen Panel for Genomic Wastewater-Based Viral Epidemiology in Uruguay.

Coronavirus Literature

Publication date: Jan 09, 2025 Human respiratory and enteric viruses are responsible for substantial morbidity and mortality worldwide. Wastewater-based epidemiology utilizing next-generation sequencing serves as an effective tool for monitoring ... Read more

January 10, 2025January 10, 2025

The anti-melanoma roles and mechanisms of tricholoma isoflavone derivative CA028.

Melanoma Literature

Publication date: Jan 09, 2025 As a form of skin cancer, melanoma’s incidence rate is continuing to rise globally. Therefore, there is an urgent need to find new agents to ... Read more

January 9, 2025January 9, 2025

Neuroligin-3 R451C induces gain-of-function gene expression in astroglia in an astroglia-enriched brain organoid model.

Autism Literature

Publication date: Jan 08, 2025 Astroglia are integral to brain development and the emergence of neurodevelopmental disorders. However, studying the pathophysiology of human astroglia using brain organoid models has been ... Read more

January 9, 2025January 9, 2025

Expression and purification of Mycobacterium tuberculosis F-dependent glucose-6-phosphate dehydrogenase enzyme using Escherichia coli.

Tuberculosis Literature

Publication date: Jan 06, 2025 Since their discovery in Mycobacterium tuberculosis (Mtb), F-dependent enzymes have been identified as both important drug targets and potential industrial biocatalysts, including for bioremediation of ... Read more

December 31, 2024December 31, 2024

Identification of virus-rich intermediate cells as crucial players in SARS-CoV-2 infection and differentiation dynamics of human airway epithelium.

Coronavirus Literature

Publication date: Oct 08, 2024 Understanding the early interactions between severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and human airway epithelial cells is essential for unraveling viral replication and spread ... Read more

December 27, 2024December 27, 2024

Tagless LysoIP for immunoaffinity enrichment of native lysosomes from clinical samples.

Parkinson's Disease Literature

Publication date: Dec 26, 2024 Lysosomes are implicated in a wide spectrum of human diseases including monogenic lysosomal storage disorders (LSDs), age-associated neurodegeneration and cancer. Profiling lysosomal content using tag-based ... Read more

December 26, 2024December 26, 2024

Trichomonas tenax detected in pleural effusion fluid: A case report.

Tuberculosis Literature

Publication date: Feb 01, 2025 Trichomonas tenax is predominant in dental caries and is commonly observed in patients with oral diseases; however, its presence in patients with pleural effusion remains ... Read more