Search Results for: Serine

January 21, 2025January 21, 2025

Enhanced Macrophage Uptake of Spray-Dried Phosphatidylserine-Loaded Microparticles for Pulmonary Drug Delivery Applications.

Publication date: Feb 01, 2025 Macrophages are an integral part of the innate immune system and act as a first line of defense to pathogens; however, macrophages can be reservoirs ... Read more

January 12, 2025January 12, 2025

Copper Chelate Targeting Externalized Phosphatidylserine Inhibits PD-L1 Expression and Enhances Cancer Immunotherapy.

Melanoma Literature

Publication date: Jan 11, 2025 Inhibitors of the PD-1/PD-L1 immune checkpoint have revolutionized cancer treatment. However, the clinical response remains limited, with only 20% of patients benefiting from treatment and ... Read more

January 9, 2025January 9, 2025

Patch Test-Positive Drug Reaction with Eosinophilia and Systemic Symptoms Syndrome Due to Cycloserine in Multidrug-Resistant Tuberculosis: A Case Report with a Review of the Literature.

Tuberculosis Literature

Publication date: Jan 07, 2025 Antitubercular treatment (ATT) is associated with multiple cutaneous adverse drug reactions. Second-line ATT is also associated with numerous adverse reactions; however, cutaneous reactions are under-reported. ... Read more

December 23, 2024December 23, 2024

Phosphorylation of annexin A2 at serine 25 is required for endothelin-1 stimulated cell proliferation and AKT activation in melanoma cells.

Melanoma Literature

Publication date: Jan 01, 2025 Endothelin (ET)-1 contributes to melanoma progression via cell proliferation, invasion, and migration. We previously reported that annexin A2 (AnxA2) binds to ET receptors. In this ... Read more

November 30, 2024November 30, 2024

NOTCH2NLC GGC intermediate repeat with serine induces hypermyelination and early Parkinson’s disease-like phenotypes in mice.

Parkinson's Disease Literature

Publication date: Nov 28, 2024 The expansion of GGC repeats (typically exceeding 60 repeats) in the 5′ untranslated region (UTR) of the NOTCH2NLC gene (N2C) is linked to N2C-related repeat ... Read more

November 29, 2024November 29, 2024

SARS-CoV-2 Genomic Variants and Their Relationship with the Expressional and Genomic Profile of Angiotensin-Converting Enzyme 2 (ACE2) and Transmembrane Serine Protease 2 (TMPRSS2).

Coronavirus Literature

Publication date: Nov 14, 2024 Over the past four years, angiotensin-converting enzyme 2 (ACE2) and transmembrane serine protease 2 (TMPRSS2) have been extensively studied, given their important role in SARS-CoV-2 ... Read more

November 29, 2024November 29, 2024

SARS-CoV-2 Genomic Variants and Their Relationship with the Expressional and Genomic Profile of Angiotensin-Converting Enzyme 2 (ACE2) and Transmembrane Serine Protease 2 (TMPRSS2).

Coronavirus Literature

November 29, 2024November 29, 2024

SARS-CoV-2 Genomic Variants and Their Relationship with the Expressional and Genomic Profile of Angiotensin-Converting Enzyme 2 (ACE2) and Transmembrane Serine Protease 2 (TMPRSS2).

Coronavirus Literature

November 11, 2024November 11, 2024

Cutaneous Melanoma: An Overview of Physiological and Therapeutic Aspects and Biotechnological Use of Serine Protease Inhibitors.

Melanoma Literature

Publication date: Aug 16, 2024 Metastatic melanoma stands out as the most lethal form of skin cancer because of its high propensity to spread and its remarkable resistance to treatment ... Read more

November 7, 2024November 7, 2024

Nucleotidyltransferase toxin MenT extends aminoacyl acceptor ends of serine tRNAs to control Mycobacterium tuberculosis growth.

Tuberculosis Literature

Publication date: Nov 06, 2024 Toxins of toxin-antitoxin systems use diverse mechanisms to inhibit bacterial growth. In this study, we characterize the translation inhibitor toxin MenT3 of Mycobacterium tuberculosis, the ... Read more