Search Results for: Sodium lauryl sulfate

January 21, 2025January 21, 2025

Inhibition of programmed cell death by melanoma cell subpopulations reveals mechanisms of melanoma metastasis and potential therapeutic targets.

Melanoma Literature

Publication date: Jan 20, 2025 Melanoma is an aggressive type of skin cancer that arises from melanocytes, the cells responsible for producing skin pigment. In contrast to non-melanoma skin cancers ... Read more

January 21, 2025January 21, 2025

A novel approach for target deconvolution from phenotype-based screening using knowledge graph.

Dr. Richard A. Blevins Literature, Informatics Literature

Publication date: Jan 18, 2025 Deconvoluting drug targets is crucial in modern drug development, yet both traditional and artificial intelligence (AI)-driven methods face challenges in terms of completeness, accuracy, and ... Read more

January 20, 2025January 20, 2025

Synergistic impact of CAG intermediate alleles in the HTT gene and microRNA dysregulation exacerbates spliceosome impairment and accelerates Tau pathology in the caudate nucleus of late-onset Alzheimer’s disease

Huntington's Disease News

Publication date: Jan 18, 2025 Background: Late-onset Alzheimer’s disease (LOAD) accounts for more than 95% of AD cases. Previously, we have described that 6% of AD patients present CAG intermediate ... Read more

January 20, 2025January 20, 2025

BIND: Large-Scale Biological Interaction Network Discovery through Knowledge Graph-Driven Machine Learning

Dr. Richard A. Blevins News, Informatics News

Publication date: Jan 18, 2025 The complex interactions between biological entities provide valuable insights into fundamental life processes, which pave the way to a deeper understanding of disease mechanisms for ... Read more

January 19, 2025January 19, 2025

Race and Ethnicity and Diffusion of Telemedicine in Medicaid for Schizophrenia Care After Onset of the COVID-19 Pandemic.

Coronavirus Literature

Publication date: Jan 02, 2025 Delivery of mental health care through telehealth (telemental health care) increased after the onset of the COVID-19 pandemic. Little is known about the speed of ... Read more

January 19, 2025January 19, 2025

Exploring the anticancer activities of Sulfur and magnesium oxide through integration of deep learning and fuzzy rough set analyses based on the features of Vidarabine alkaloid.

Melanoma Literature

Publication date: Jan 17, 2025 Drug discovery and development is a challenging and time-consuming process. Laboratory experiments conducted on Vidarabine showed IC 6. 97 ug∕mL, 25. 78 ug∕mL, and ˃ ... Read more

January 19, 2025January 19, 2025

Engineering a membrane protein chaperone to ameliorate the proteotoxicity of mutant huntingtin.

Huntington's Disease Literature

Publication date: Jan 17, 2025 Toxic protein aggregates are associated with various neurodegenerative diseases, including Huntington’s disease (HD). Since no current treatment delays the progression of HD, we develop a ... Read more

January 18, 2025January 18, 2025

Protocol for evaluating humoral immune responses in mice following SARS-CoV-2 vaccination.

Coronavirus Literature

Publication date: Jan 15, 2025 Binding and neutralizing antibodies are critical indicators of protection against viral pathogens and are essential for assessing the immunogenicity and efficacy of a vaccine. Here, ... Read more

January 18, 2025January 18, 2025

Prevalence and correlates of severe anxiety among front-line nurses during and after the COVID-19 pandemic: a large-scale multi-center study.

Coronavirus Literature

Publication date: Jan 15, 2025 Nurses have been at the forefront of the battle against the COVID-19 pandemic, facing extended work hours and heightened stress, predisposing them to psychological distress. ... Read more

January 18, 2025January 18, 2025

Comprehensive investigation of matrix metalloproteinases in skin cutaneous melanoma: diagnostic, prognostic, and therapeutic insights.

Melanoma Literature

Publication date: Jan 16, 2025 The dysregulation of matrix metalloproteinases (MMPs) in skin cutaneous melanoma (SKCM) represents a critical aspect of tumorigenesis. In this study, we investigated the diagnostic, prognostic, ... Read more