Publication date: May 01, 2019 Central nervous system (CNS) inflammatory demyelinating disease (IDD) is an immune-mediated disease that is pathologically characterized by demyelination and inflammatory infiltration in the CNS and ... Read more

Publication date: May 01, 2019 Central nervous system (CNS) inflammatory demyelinating disease (IDD) is an immune-mediated disease that is pathologically characterized by demyelination and inflammatory infiltration in the CNS and ... Read more

Publication date: Jan 29, 2019 The presence of ≥3 oligoclonal bands (OCB) in the cerebrospinal fluid (CSF) without corresponding bands in serum represents a definite pathological pattern, whereas the clinical ... Read more

Publication date: Apr 01, 2019 Younger age, male sex and presence of spinal cord lesion(s) increase the risk of conversion from radiologically isolated syndrome (RIS) to relapsing-remitting multiple sclerosis (RRMS). ... Read more

Publication date: Mar 08, 2019 Cerebrospinal fluid (CSF) plays an important role in the clearance of solutes and maintenance of brain homeostasis. C-PiB PET was recently proposed as a tool ... Read more

Publication date: Mar 11, 2019 Long-term outcome in multiple sclerosis (MS) depends on early treatment. In patients with acute optic neuritis (ON), an early inflammatory event, we investigated markers in ... Read more

Publication date: Feb 12, 2019 B-cells are key contributors to chronic autoimmune pathology in multiple sclerosis (MS). Clonally related B-cells exist in the cerebrospinal fluid (CSF), meninges, and central nervous ... Read more

Publication date: Feb 05, 2019 The tryptophan-kynurenine-NAD+ pathway is closely associated with regulation of immune cells toward less inflammatory phenotypes and may exert neuroprotective effects. Investigating its regulation in CNS ... Read more