Search Results for: Syndrome

August 14, 2019August 14, 2019

Female sex and brain-selective estrogen benefit α-synuclein tetramerization and the PD-like motor syndrome in 3K transgenic mice.

Publication date: Aug 12, 2019 Many studies report a higher risk for Parkinson’s disease (PD) and younger age of onset in men. This, and the fact that the neuropathological process ... Read more

August 10, 2019August 10, 2019

Neurobiological perspective of 22q11.2 deletion syndrome.

Parkinson's Disease Literature

Publication date: Aug 05, 2019 22q11.2 deletion syndrome is characterised by a well defined microdeletion that is associated with a high risk of neuropsychiatric disorders, including intellectual disability, schizophrenia, attention-deficit ... Read more

August 9, 2019August 9, 2019

Non-Opioid Neurotransmitter Systems that Contribute to the Opioid Withdrawal Syndrome: A Review of Preclinical and Human Evidence.

Opioids Literature

Publication date: Aug 07, 2019 Opioid misuse and abuse is a major international public health issue. Opioid use disorder (OUD) is largely maintained by a desire to suppress aversive opioid ... Read more

August 7, 2019August 7, 2019

Families with BAP1-Tumor Predisposition Syndrome in The Netherlands: Path to Identification and a Proposal for Genetic Screening Guidelines.

Melanoma Literature

Publication date: Aug 04, 2019 Germline pathogenic variants in the BRCA1-associated protein-1 (BAP1) gene cause the BAP1-tumor predisposition syndrome (BAP1-TPDS, OMIM 614327). BAP1-TPDS is associated with an increased risk of ... Read more

July 26, 2019July 26, 2019

Assessment of the risk and characterization of non-melanoma skin cancer in Kindler syndrome: study of a series of 91 patients.

Melanoma Literature

Publication date: Jul 24, 2019 Kindler Syndrome (KS) is a rare genodermatosis characterized by skin fragility, skin atrophy, premature aging and poikiloderma. It is caused by mutations in the FERMT1 ... Read more

July 26, 2019July 26, 2019

Standardization of State Definitions for Neonatal Abstinence Syndrome Surveillance and the Opioid Crisis.

Opioids Literature

Publication date: Jul 18, 2019 Rates of neonatal abstinence syndrome (NAS) have increased fivefold in the past decade. To address this expanding and complex issue, state public health agencies have ... Read more

July 26, 2019July 26, 2019

CRISPRed Exosomes Correct Rett Syndrome Communication Breakdown

Huntington's Disease News

Publication date: Jul 26, 2019 The first two approaches, CRISPR/Cas9 gene editing and use of human induced pluripotent stem (iPS) cells to generate specialized cells that are hard to culture, ... Read more

July 22, 2019July 22, 2019

The ACT NOW Clinical Practice Survey: Gaps in the Care of Infants With Neonatal Opioid Withdrawal Syndrome.

Opioids Literature

Publication date: Jul 19, 2019 The incidence of neonatal opioid withdrawal syndrome (NOWS) has increased fivefold over the last 10 years. Standardized NOWS care protocols have revealed many improved patient ... Read more

July 16, 2019July 16, 2019

A prospective, observational study on conversion of clinically isolated syndrome to multiple sclerosis during 4-year period (MS NEO study) in Taiwan.

Multiple Sclerosis Literature

Publication date: Aug 01, 2018 CIS to MS conversion rates vary depending on population cohorts, initial manifestations, and durations of follow-up. To investigate conversion rate of patients from CIS to ... Read more

July 12, 2019July 12, 2019

Drug Treatment of Clinically Isolated Syndrome.

Multiple Sclerosis Literature

Publication date: Jul 09, 2019 Multiple sclerosis (MS) is an autoimmune disease of the central nervous system (CNS) that leads to inflammation, demyelination and ultimately axonal degeneration. In most cases, ... Read more