Search Results for: TYRO3

September 13, 2018September 13, 2018

The TAM receptor TYRO3 is a critical regulator of myelin thickness in the central nervous system.

Publication date: Sep 12, 2018 Multiple sclerosis (MS) is an autoimmune, demyelinating disease of the central nervous system (CNS). Major deficits arise in MS patients due to an inability to ... Read more

November 11, 2019November 11, 2019

How can hospitals use real-time analytics to improve care quality, delivery? The sky’s the limit

Precision Medicine News

Publication date: Nov 11, 2019 During a panel titled “Real-Time Analytics to Improve Operational Efficiency and Clinical Care” at the Becker’s Hospital Review Health IT + Revenue Cycle conference in ... Read more

October 31, 2019October 31, 2019

Focal segmental glomerulosclerosis ACTN4 mutants binding to actin: regulation by phosphomimetic mutations.

Melanoma Literature

Publication date: Oct 29, 2019 Natural mutations such as lysine 255 to glutamic acid (K to E), threonine 259 to isoleucine (T to I) and serine 262 to proline (S ... Read more

October 1, 2019October 1, 2019

Moving Beyond ‘Therapy’ and ‘Enhancement’ in the Ethics of Gene Editing.

Precision Medicine Literature

Publication date: Oct 01, 2019 Since the advent of recombinant DNA technology, expectations (and trepidations) about the potential for altering genes and controlling our biology at the fundamental level have ... Read more

August 29, 2019August 29, 2019

TAM Family Receptor kinase inhibition reverses MDSC-mediated suppression and augments anti-PD-1 therapy in melanoma.

Melanoma Literature

Publication date: Aug 26, 2019 Myeloid cell receptor tyrosine kinases (RTK) TYRO3, AXL and MERTK and their ligands, Gas 6 and Protein S, physiologically suppress innate immune responses, including in ... Read more

July 25, 2019July 25, 2019

Rutin and Selenium Co-administration Reverse 3-Nitropropionic Acid-Induced Neurochemical and Molecular Impairments in a Mouse Model of Huntington’s Disease.

Huntington's Disease Literature

Publication date: Jul 22, 2019 Systemic administration of 3-nitropropionic acid (3-NPA) is commonly used to induce Huntington’s disease (HD)-like symptoms in experimental animals. Here, the potential neuroprotective efficiency of rutin ... Read more

July 9, 2019July 9, 2019

Why the absence of hope may be hurting Huntington’s disease research

Huntington's Disease News

Publication date: Jul 09, 2019 The author of those words is George Huntington, the physician credited with defining the disease that carries his name, Huntington’s Disease, a genetic, invariably fatal, ... Read more

July 4, 2019July 4, 2019

MERTK acts as a costimulatory receptor on human CD8+ T cells.

Melanoma Literature

Publication date: Jul 02, 2019 The TAM family of receptor tyrosine kinases (TYRO3, AXL, and MERTK) is known to be expressed on antigen-presenting cells and function as oncogenic drivers and ... Read more

May 12, 2019

The Right Way to Wear Sunscreen

Melanoma News

Publication date: May 12, 2019 And although genetics can certainly affect your skin cancer risk, proper use of sun protection plays a huge role in prevention. In fact, a study ... Read more

May 10, 2019May 10, 2019

Over-ground walking or robot-assisted gait training in people with .multiple sclerosis: does the effect depend on baseline walking speed and disease related disabilities? A systematic review and meta-regression.

Multiple Sclerosis Literature

Publication date: May 08, 2019 It was suggested that robot-assisted gait training (RAGT) should not be routinely provided to disabled patients in place of conventional over-ground walking training (CGT). There ... Read more