Search Results for: Translation

January 9, 2025January 9, 2025

Social Disengagement in Post-Pandemic China: A Translation, Validation and Cross-Cultural Comparison of the Pandemic Disengagement Syndrome Scale.

Publication date: Feb 01, 2025 In contrast to abundant research on the various acute mental effects of COVID-19, the long-term influences of the pandemic are still underexplored in China owing ... Read more

January 7, 2025January 7, 2025

Quantifying VMAT2 target occupancy at effective valbenazine doses and comparing to a novel VMAT2 inhibitor: a translational PET study.

Huntington's Disease Literature

Publication date: Jan 05, 2025 Positron emission tomography (PET) is frequently used to obtain target occupancy (%TO) of central nervous system (CNS) drug candidates during clinical development. Obtaining %TO with ... Read more

January 3, 2025January 3, 2025

Clinical Translational Research on Personalized Cancer Vaccines Combined with Radiation Therapy.

Melanoma News

Publication date: Dec 31, 2024 Evaluation and exploration of the phase I/II clinical safety and efficacy of personalized FAST cancer vaccine combined with radiotherapy. Concepts Keywords Cancer immunogenic cell death ... Read more

December 29, 2024December 29, 2024

Definitions, epidemiology, and outcomes of persistent/chronic critical illness: a scoping review for translation to clinical practice.

Coronavirus Literature

Publication date: Dec 28, 2024 Medical advances in intensive care units (ICUs) have resulted in the emergence of a new patient population-those who survive the initial acute phase of critical ... Read more

December 24, 2024December 24, 2024

Initial Validation of the Mandarin Translation of the Stanford Social Dimensions Scale (SSDS).

Autism Literature

Publication date: Dec 23, 2024 This study aimed to validate the Mandarin translation of the Stanford Social Dimensions Scale (SSDS). The initial validation sample consisted of 480 children with Autism ... Read more

December 21, 2024December 21, 2024

Cross-cultural translation, validation, and responsiveness of the Pittsburgh Fatigability Scale – Italian version (PFS-I) in a mixed-sample of older adults.

Parkinson's Disease Literature

Publication date: Dec 19, 2024 Older adults experience fatigue which impacts health-related quality of life. The Pittsburgh Fatigability Scale (PFS) was specifically designed to assess perceived physical and mental fatigability ... Read more

December 21, 2024December 21, 2024

A Review on Circular RNA Translation and Its Implications in Disease.

Coronavirus Literature

Publication date: Dec 20, 2024 The mRNA vaccine has emerged as a powerful tool against viral infection during the coronavirus disease 2019 (COVID-19) pandemic. In the post-COVID-19 era, the applications ... Read more

December 21, 2024December 21, 2024

Translation, Cross-Cultural Adaptation and Validation of the Karaduman Chewing Performance Scale for the Italian Paediatric Population.

Autism Literature

Publication date: Feb 01, 2025 Chewing is a fundamental motor activity, but there is no specific assessment tool in Italian for paediatric rehabilitation. The Karaduman Chewing Performance Scale (KCPS) is ... Read more

December 14, 2024December 14, 2024

Upregulation of porcine epidemic diarrhea virus (PEDV) RNA translation by the nucleocapsid protein.

Coronavirus Literature

Publication date: Jan 01, 2025 The role of coronaviral nucleocapsid (N) protein in regulating viral translation remains poorly understood. Here, we showed that the N protein of porcine epidemic diarrhea ... Read more

December 10, 2024December 10, 2024

Backtranslation of human RNA biosignatures of tuberculosis disease risk into the preclinical pipeline is condition dependent.

Tuberculosis Literature

Publication date: Dec 09, 2024 It is unclear whether human progression to active tuberculosis disease (TB) risk signatures are viable endpoint criteria for evaluations of treatments in development. TB is ... Read more