Search Results for: Trial

May 15, 2025

Safety and tolerability of intravenous liposomal GM1 in patients with Parkinson disease: A single-center open-label clinical phase I trial (NEON trial).

Publication date: May 13, 2025 Parkinson disease (PD) is a chronic progressive neurodegenerative disorder leading to motor and non-motor impairment, often resulting in severe loss of quality of life. There ... Read more

May 15, 2025May 15, 2025

Herantis Pharma doses final cohort in phase 1b trial of HER-096 for Parkinson’s disease

Parkinson's Disease News

Publication date: May 15, 2025 Trial progresses towards topline data expected later in the yearHerantis Pharma has dosed the first patients in the final cohort of its phase 1b clinical ... Read more

May 15, 2025

Grain Moxibustion Treatment on Insomnia: a Randomized Controlled Trial

Major Depressive Disorder News

Publication date: May 13, 2025 This trial intends to observe the clinical efficacy and safety of grain moxibustion at Baihui(GV20), Xinshu(BL15) and Pishu(BL20) in the treatment of insomnia. Concepts Keywords ... Read more

May 15, 2025

Evaluating an Integrated Habituation Programme for Enhancing Dental Examination Acceptance in Children With Autism Spectrum Disorder: An Effectiveness Trial

Autism News

Publication date: May 09, 2025 The goal of this effectiveness trial is to investigate if an integrated dental habituation programme can enhance acceptance of a clinical dental examination in children ... Read more

May 15, 2025

The Influence of the COVID-19 Pandemic in NK Cell Subpopulations from CML Patients Enrolled in the Argentina Stop Trial.

Coronavirus Literature

Publication date: Apr 23, 2025 Treatment-free remission (TFR) is a key therapeutic goal for chronic myeloid leukemia (CML) patients in deep molecular response (DMR). While predicting patient outcome remains challenging, ... Read more

May 15, 2025May 15, 2025

Tocilizumab, sarilumab and anakinra in critically ill patients with COVID-19: a randomised, controlled, open-label, adaptive platform trial.

Coronavirus Literature

Publication date: May 13, 2025 Tocilizumab improves outcomes in critically ill patients with COVID-19. Whether other immune-modulator strategies are equally effective or better is unknown. We investigated treatment with tocilizumab, ... Read more

May 15, 2025

The cost effectiveness of a multidomain intervention on physical, cognitive, vascular, dietary and psychosocial outcomes among community dwelling older adults with cognitive frailty in Malaysia: The AGELESS Trial.

Coronavirus Literature

Publication date: May 13, 2025 Cognitive frailty (CF) in older adults is a potentially reversible syndrome that may benefit from lifestyle-based multidomain interventions. This study assessed the AGELESS intervention’s impact ... Read more

May 15, 2025May 15, 2025

Transforming healthcare by prioritizing qualitative and quantitative clinical trial evidence: evaluating the Aging, Community and Health Research Unit’s Community Partnership Program for Older Adults (ACHRU-CPP).

Coronavirus Literature

Publication date: May 13, 2025 This study aimed to test the effectiveness and implementation of a complex integrated care intervention for older adults. We collected both quantitative and qualitative data, ... Read more

May 15, 2025May 15, 2025

Tuberculosis disease characteristics associated with mortality, severe morbidity and unsuccessful treatment in people living with HIV treated for tuberculosis – a secondary analysis of the ANRS 12300 Reflate TB2 trial.

Tuberculosis Literature

Publication date: May 14, 2025 Tuberculosis is a severe disease, not only due to its lethality but also to a significant morbidity occurring in people living with HIV (PLWH). If ... Read more

May 14, 2025

“Amazonian Dance for Parkinson”: a Protocol Study for a Randomized Clinical Trial on Motor and Non-motor Symptoms of People With Parkinson’s.

Parkinson's Disease News

Publication date: May 02, 2025 This randomized controlled trial aims to evaluate the effects of a 12-week Amazonian dance program on cognitive and motor symptoms in people with Parkinson’s disease ... Read more