Publication date: Feb 01, 2025 Chylothorax is the accumulation of chyle in the pleural cavity. Tuberculosis is one of its rarest causes. Diagnosis of chylothorax can be made by evaluation ... Read more

Publication date: Feb 04, 2025 Discriminating Crohn’s disease (CD) with latent tuberculosis infection (LTBI) from intestinal tuberculosis (ITB) in tuberculosis-endemic regions remains challenging. To assess whether targeted next-generation sequencing (tNGS) ... Read more

Publication date: Feb 05, 2025 Accelerated tuberculosis drug discovery has increased the number of plausible multidrug regimens. Testing every drug combination in vivo is impractical, and varied experimental conditions make ... Read more

Publication date: Feb 05, 2025 China is a high-burden country for multidrug-resistant tuberculosis/rifampin-resistant tuberculosis (MDR/RR-TB). Fluoroquinolones (FQs) are key drugs for the treatment of patients with MDR/RR-TB. However, research on ... Read more

Publication date: Feb 05, 2025 The rise of multidrug-resistant tuberculosis (MDR-TB) remains a critical public health challenge, particularly in developing countries like Ethiopia. This systematic review and meta-analysis aimed to ... Read more

Publication date: Feb 05, 2025 Genetic variations in endoplasmic reticulum aminopeptidase (ERAP1, ERAP2) genes are associated with the pathogenesis of multiple diseases, including infectious diseases. The objective of our study ... Read more

Publication date: Feb 03, 2025 Open Access PDF Concepts Keywords Cyclohexadiene Acid Photodynamic Aminophenyl Pulmonary Chem Therapy Curr Tuberculosis Cyclohexadiene Drug Interactions Med Mycolic Photodynamic Pulmonary Resistant Targeted Therapy Tuberculosis ... Read more

Publication date: Feb 04, 2025 Mycobacterium tuberculosis (Mtb) contains potential G-quadruplex (PGQ) motifs in the genes espK and cyp51, which are crucial for the bacteria’s virulence within host cells. Aminoglycoside ... Read more

Publication date: Feb 04, 2025 The secreted Chorismate mutase enzyme of Mycobacterium tuberculosis (*MtbCM) is an underexplored potential target for the development of new antitubercular agents that are increasingly needed ... Read more

Publication date: Feb 04, 2025 Tuberculosis (TB) is notoriously difficult to treat, likely due to the complex host-pathogen interactions driven by pathogen heterogeneity. An understudied area of TB pathogenesis is ... Read more