Search Results for: Virus

May 17, 2019May 17, 2019

Abscopal effect when combining oncolytic adenovirus and checkpoint inhibitor in a humanized NOG mouse model of melanoma.

Melanoma Literature

Publication date: May 13, 2019 Melanoma, an immunogenic tumor, is the first indication where oncolytic viruses are now becoming part of clinical practice. ONCOS-102, a transgened adenovirus, have shown to ... Read more

May 17, 2019May 17, 2019

Abscopal effect when combining oncolytic adenovirus and checkpoint inhibitor in a humanized NOG mouse model of melanoma.

Melanoma Literature

May 17, 2019May 17, 2019

Perceptions and self-reported competency related to testing, management and treatment of hepatitis C virus infection among physicians prescribing opioid agonist treatment: The C-SCOPE study.

Opioids Literature

Publication date: Jan 01, 2019 This study evaluated competency related to HCV testing, management and treatment among physicians practicing in clinics offering opioid agonist treatment (OAT). C-SCOPE is a study ... Read more

May 11, 2019May 11, 2019

Scientists link ancient viruses to the chronic inflammation causing multiple sclerosis

Multiple Sclerosis News

Publication date: May 11, 2019 Little is known about why the immune system turns on its own cells in autoimmune conditions, but scientists at Institut Pasteur say they have discovered ... Read more

May 10, 2019May 10, 2019

Expression of endogenous retroviruses reflects increased usage of atypical enhancers in T cells.

Multiple Sclerosis Literature

Publication date: May 08, 2019 Several autoimmune diseases including multiple sclerosis (MS) cause increased transcription of endogenous retroviruses (HERVs) normally repressed by heterochromatin. In parallel, HERV-derived sequences were reported to ... Read more

May 9, 2019May 9, 2019

Reactivation of Hepatitis B Virus With Immune-Escape Mutations After Ocrelizumab Treatment for Multiple Sclerosis.

Multiple Sclerosis Literature

Publication date: Jan 01, 2019 Ocrelizumab is an anti-CD20 monoclonal antibody for the treatment of multiple sclerosis (MS) that is closely related to rituximab. We describe a case of hepatitis ... Read more

May 3, 2019May 3, 2019

Evidence from genome wide association studies implicates reduced control of Epstein-Barr virus infection in multiple sclerosis susceptibility.

Multiple Sclerosis Literature

Publication date: Apr 30, 2019 Genome wide association studies have identified > 200 susceptibility loci accounting for much of the heritability of multiple sclerosis (MS). Epstein-Barr virus (EBV), a memory B ... Read more

April 18, 2019April 18, 2019

Self-Limited Cytomegalovirus Infection During Natalizumab Treatment for Multiple Sclerosis.

Multiple Sclerosis Literature

Publication date: Jan 03, 2019 Natalizumab is indicated as monotherapy for the treatment of relapsing-remitting multiple sclerosis; it prevents outbreaks and delays the progression of physical disability. Here, we report ... Read more

April 11, 2019April 11, 2019

Combination of immunogenic oncolytic adenovirus ONCOS-102 with anti-PD-1 pembrolizumab exhibits synergistic antitumor effect in humanized A2058 melanoma huNOG mouse model.

Melanoma Literature

Publication date: Jun 27, 2018 Malignant melanoma is an aggressive type of skin cancer whose incidence is increasing globally. Although surgery is effective in early stage melanoma, patients with advanced ... Read more

March 29, 2019March 29, 2019

Interferon Gamma Inhibits Varicella-Zoster Virus Replication in a Cell Line-Dependent Manner.

Melanoma Literature

Publication date: Mar 27, 2019 The major immediate-early IE62 protein of varicella-zoster virus (VZV) is delivered to newly infected cell nuclei, where it initiates VZV replication by transactivating viral immediate-early ... Read more