Search Results for: apoptosis

March 24, 2025March 24, 2025

Tianma Gouteng Decoction improve neuronal synaptic plasticity and oligodendrocyte apoptosis in Parkinson’s disease mice.

Publication date: May 01, 2025 Parkinson’s disease (PD) is a complex and multifactorial disorder of the nervous system. Tianma Gouteng Decoction (TGD) is a clinical prescription of traditional Chinese medicine ... Read more

March 21, 2025March 21, 2025

Regulation of FOXM1 by HDAC3 Inhibition Ameliorates Macrophage Endoplasmic Reticulum stress and Apoptosis in Mycobacterium tuberculosis Infection.

Tuberculosis Literature

Publication date: Mar 01, 2025 Mycobacterium tuberculosis (Mtb) infection may induce significant damage to the host lung tissues. Endoplasmic reticulum stress (ERS) and apoptosis of macrophages are considered key factors ... Read more

March 19, 2025March 19, 2025

ROS Regulate Rotenone-induced SH-SY5Y Dopamine Neuron Death Through Ferroptosis-mediated Autophagy and Apoptosis.

Parkinson's Disease Literature

Publication date: Mar 18, 2025 Rotenone, a plant-derived natural insecticide, is widely used to induce Parkinson’s disease (PD) models. However, the mechanisms of rotenone-induced cell death remain unclear. Here, we ... Read more

March 19, 2025March 19, 2025

Ginsenoside Rb1 inhibits porcine epidemic diarrhea virus replication through suppressing S1 protein mediated the MAPK/ERK pathway and reducing apoptosis.

Coronavirus Literature

Publication date: Apr 01, 2025 Porcine epidemic diarrhea virus (PEDV) causes vomiting, dehydration, and diarrhea in piglets, seriously threatening their survival and development and causing huge economic losses to the ... Read more

March 15, 2025March 15, 2025

Porcine epidemic diarrhea virus induces mitophagy to inhibit the apoptosis and activation of JAK/STAT1 pathway.

Coronavirus Literature

Publication date: Apr 01, 2025 Porcine epidemic diarrhea virus (PEDV) infection leads to immunosuppression and clinical symptoms in piglets, including vomiting, watery diarrhea, dehydration, and even death. Mitophagy sustains mitochondrial ... Read more

March 15, 2025March 15, 2025

Combinational Inhibition of MEK and AKT Synergistically Induces Melanoma Stem Cell Apoptosis and Blocks NRAS Tumor Growth.

Melanoma Literature

Publication date: Feb 10, 2025 Malignant melanoma is a lethal skin cancer containing melanoma-initiating cells (MICs), implicated in tumorigenesis, invasion, and drug resistance, and characterized by an elevated expression of ... Read more

March 15, 2025March 15, 2025

Combinational Inhibition of MEK and AKT Synergistically Induces Melanoma Stem Cell Apoptosis and Blocks NRAS Tumor Growth.

Melanoma Literature

March 15, 2025March 15, 2025

Combinational Inhibition of MEK and AKT Synergistically Induces Melanoma Stem Cell Apoptosis and Blocks NRAS Tumor Growth.

Melanoma Literature

March 15, 2025March 15, 2025

Combinational Inhibition of MEK and AKT Synergistically Induces Melanoma Stem Cell Apoptosis and Blocks NRAS Tumor Growth.

Melanoma Literature

March 14, 2025March 14, 2025

Overexpression of LMOD1 induces oxidative stress and enhances cell apoptosis of melanoma through the RIG-I like receptor pathway.

Melanoma Literature

Publication date: Mar 10, 2025 Oxidative stress is crucial in the development of cutaneous melanoma, but its role in melanoma is controversial. We aimed to identify melanoma-associated targets and understand ... Read more