Publication date: Aug 19, 2019 Calcium signaling is critical to neuronal function and regulates highly diverse processes such as gene transcription, energy production, protein handling, and synaptic structure and function. ... Read more

Publication date: Aug 19, 2019 Calcium signaling is critical to neuronal function and regulates highly diverse processes such as gene transcription, energy production, protein handling, and synaptic structure and function. ... Read more

Publication date: May 29, 2019 Defects in nucleocytoplasmic transport have been associated with several neurodegenerative disorders and, in particular, the formation of pathological protein aggregates characteristic for the respective disease. ... Read more

Publication date: Apr 23, 2019 White matter abnormalities are a nearly universal pathological feature of neurodegenerative disorders including Huntington disease (HD). A long-held assumption is that this white matter pathology ... Read more

Publication date: Mar 26, 2019 Mitochondrial fragmentation and bioenergetic failure manifest in Huntington’s disease (HD), a fatal neurodegenerative disease. The factors that couple mitochondrial fusion/fission with bioenergetics and their impacts ... Read more

Publication date: Feb 06, 2019 High levels of oxidative stress is detected in neurons affected by many neurodegenerative diseases, including huntington’s disease. Many of these diseases also show neuronal cell ... Read more