Search Results for: depression

December 9, 2024December 9, 2024

Four weeks standard vs. one week accelerated intermittent Theta Burst Stimulation for the treatment of depression – A retrospective analysis.

Publication date: Feb 28, 2025 Intermittent Theta Burst Stimulation (iTBS), a specific form of repetitive transcranial magnetic stimulation (rTMS) is increasingly used for treating affective disorders. Accelerated iTBS protocols (aiTBS) ... Read more

December 9, 2024December 9, 2024

Acceptability, tolerability and safety of the BRIGhTMIND trial: Connectivity-guided intermittent theta-burst stimulation versus F3- repetitive transcranial magnetic stimulation for treatment-resistant depression.

Major Depressive Disorder Literature

Publication date: Jan 01, 2025 The BRIGhTMIND study was a double-blind RCT comparing repetitive transcranial magnetic stimulation at a standard simulation site (the “F3” location given by the International 10-20 ... Read more

December 9, 2024December 9, 2024

Depression unveiled: Insights into etiology and animal models for behavioral assessment, exploring the multifactorial nature and treatment of depression.

Coronavirus Literature

Publication date: Jan 15, 2025 Over the past century, significant shifts in daily living have led to an increased prevalence of mental disorders, often linked to hormonal imbalances. Among these, ... Read more

December 8, 2024December 8, 2024

Examining the impact of comorbid posttraumatic stress disorder on ketamine’s real-world effectiveness in treatment-resistant depression.

Major Depressive Disorder Literature

Publication date: Dec 05, 2024 Depression with comorbid posttraumatic stress disorder (PTSD) is associated with more severe symptoms and a reduced response to traditional treatments. Although ketamine shows promise as ... Read more

December 8, 2024December 8, 2024

Genome-wide methylome-based molecular pathologies associated with depression and suicide.

Major Depressive Disorder Literature

Publication date: Dec 07, 2024 Major depressive disorder (MDD) is a debilitating disorder. Suicide attempts are 5-times higher in MDD patients than in the general population. Interestingly, not all MDD ... Read more

December 8, 2024December 8, 2024

Poor Sleep is Common in Treatment-Resistant Late-life Depression and Associated With Poorer Antidepressant Response: Findings From the OPTIMUM Clinical Trial.

Major Depressive Disorder Literature

Publication date: Jan 01, 2025 Adults with treatment-resistant late-life depression (TRLLD) have high rates of sleep problems; however, little is known about the occurrence and change in sleep during pharmacotherapy ... Read more

December 8, 2024December 8, 2024

Late Life Depression is Not Associated With Alzheimer-Type Tau: Preliminary Evidence From a Next-Generation Tau Ligand PET-MR Study.

Major Depressive Disorder Literature

Publication date: Jan 01, 2025 To investigate whether tau accumulation is higher in late life depression (LLD) compared to non-depressed cognitively unimpaired (CU) older adults. To situate these findings in ... Read more

December 8, 2024December 8, 2024

Spermidine alleviates depression via control of the stress response

Major Depressive Disorder News

Publication date: Dec 06, 2024 Depression is a stress-associated disorder, and it represents a major global health issue. Its pathophysiology is complex and remains insufficiently understood, with current medications often ... Read more

December 7, 2024December 7, 2024

Psilocybin Therapy for Clinicians With Symptoms of Depression From Frontline Care During the COVID-19 Pandemic: A Randomized Clinical Trial.

Coronavirus Literature

Publication date: Dec 02, 2024 The psychological morbidity experienced by physicians, advanced practice practitioners (APPs), and nurses from working during the COVID-19 pandemic includes burnout, depression, and posttraumatic stress disorder ... Read more

December 7, 2024December 7, 2024

Effect of Mediterranean diet and physical activity on healthcare professional depression, burnout and professional fulfillment during COVID-19.

Coronavirus Literature

Publication date: Dec 06, 2024 Objectives. The mental health of healthcare professionals, especially during the COVID-19 pandemic, is a critical concern. This study investigates the prevalence of burnout and professional ... Read more