Publication date: Jul 16, 2019 In this study, we aimed to explore the mechanism of glutathione peroxidase 3 (GPX3) in the growth of malignant melanoma (MM) cells by hypoxia-inducible factor-1α ... Read more

Publication date: Jul 10, 2019 Sirtuin-1 and -3 (SIRT1 and SIRT3) are important nicotinamide adenine dinucleotide (NAD )-dependent deacetylases known to regulate a variety of cellular functions. Studies have shown ... Read more

Publication date: Jul 01, 2019 Nanosecond pulsed electric fields (nsPEFs) showed an inhibitory effect on proliferation of malignant melanoma. In this study, the growth of melanoma were inhibited by changing ... Read more

Publication date: Jul 01, 2019 Nanosecond pulsed electric fields (nsPEFs) showed an inhibitory effect on proliferation of malignant melanoma. In this study, the growth of melanoma were inhibited by changing ... Read more

Publication date: Jun 30, 2019 The majority of melanomas carry an oncogenic BRAF mutation (BRAF), which results in constitutive kinase activity driving melanoma proliferation. While inhibitors of BRAF (BRAFi) effectively ... Read more

Publication date: Jun 27, 2019 Background: UV exposure-induced oxidative stress is implicated as a driving mechanism for melanoma. Increased oxidative stress results in DNA damage and epigenetic dysregulation. Accordingly, we ... Read more

Publication date: Jun 25, 2019 Melanoma skin cancer is one of the main causes of male cancer-related deaths worldwide. It has been suggested that miR-330-5p can act as a tumor ... Read more

Publication date: Jun 17, 2019 Podoplanin (PDPN), a transmembrane O-glycoprotein, is up-regulated in many tumors and is involved in tumor metastasis and malignant progression. In previous studies, we generated a ... Read more