Search Results for: growth

January 24, 2021January 24, 2021

SHANK2 mutations impair apoptosis, proliferation and neurite outgrowth during early neuronal differentiation in SH-SY5Y cells.

Autism Literature

Publication date: Jan 22, 2021 SHANK2 mutations have been identified in individuals with neurodevelopmental disorders, including intellectual disability and autism spectrum disorders (ASD). Using CRISPR/Cas9 genome editing, we obtained SH-SY5Y ... Read more

January 24, 2021January 24, 2021

Autism: Growth & Transitioning to Adulthood

Autism Media

Publication date: Jan 22, 2021 Join Dr. Holmes as she discusses autism and transition in adulthood. Ron Sandison shared, “85% of people on the autism spectrum with advanced degrees in ... Read more

January 12, 2021January 12, 2021

Organoids show how mutations in top autism gene may lead to brain overgrowth in people

Autism News

Publication date: Jan 12, 2021 The loss of CHD8, a top autism gene, speeds up the production of certain neurons and leads to overgrowth in brain organoids – spheres of ... Read more

January 10, 2021January 10, 2021

Measurement of 45 cytokine, chemokine and growth factors in established cell culture supernatants and autologous serum from advanced melanoma patients.

Melanoma Literature

Publication date: Jan 09, 2021 Melanoma is one of the most aggressive forms of human cancer and its incidence has significantly increased worldwide over the last decades. This neoplasia has ... Read more

January 10, 2021January 10, 2021

Fibroblast Growth Factor 9 Stimulates Neuronal Length Through NF-kB Signaling in Striatal Cell Huntington's Disease Models.

Huntington's Disease Literature

Publication date: Jan 09, 2021 Proper development of neuronal cells is important for brain functions, and impairment of neuronal development may lead to neuronal disorders, implying that improvement in neuronal ... Read more

January 1, 2021January 1, 2021

The Ubiquitin Specific Protease USP18 Promotes Lipolysis, Fatty Acid Oxidation and Lung Cancer Growth.

Melanoma Literature

Publication date: Dec 30, 2020 Ubiquitin specific protease18 (USP18), previously known as UBP43, is the Interferon-Stimulated Gene 15 (ISG15) deconjugase. USP18 removes ISG15 from substrate proteins. This study reports that ... Read more

December 28, 2020December 28, 2020

Beta2 glycoprotein I-derived therapeutic peptides induce sFlt-1 secretion to reduce melanoma vascularity and growth.

Melanoma Literature

Publication date: Dec 28, 2020 Melanoma, a form of skin cancer, is one of the most common cancers in young men and women. Tumors require angiogenesis to provide oxygen and ... Read more

December 24, 2020December 24, 2020

Platelet-derived growth factor BB: A potential diagnostic blood biomarker for differentiating bipolar disorder from major depressive disorder

Major Depressive Disorder News

Publication date: Dec 22, 2020 In small samples from patients with BD and MDD and healthy controls (HCs), an initial SOMAscan proteomics assay of 1,311 proteins suggested differences in serum ... Read more

December 23, 2020December 23, 2020

BAP1 deletion abrogates growth and metastasis of murine cutaneous melanoma.

Melanoma Literature

Publication date: Dec 17, 2020 Although germline mutations in BRCA-associated protein-1 (BAP1) predispose to cutaneous melanoma (CM), BAP1 is rarely mutated in primary CM outside the familial context. The role ... Read more

December 10, 2020December 10, 2020

(S)-(-)-N-[2-(3-Hydroxy-2-oxo-2,3-dihydro-1H-indol-3-yl)-ethyl]-acetamide inhibits melanoma cell growth through inducing apoptosis and autophagy.

Melanoma Literature

Publication date: Dec 07, 2020 Melanoma is the most lethal form of skin cancer with the incidence drastically increasing over the past several decades. (S)-(-)-N--acetamide (SA) was a new compound ... Read more