Search Results for: immune tolerance

July 22, 2022July 22, 2022

Cationic nanoparticles enhance T cell tumor infiltration and antitumor immune responses to a melanoma vaccine.

Melanoma Literature

Publication date: Jul 22, 2022 In clinical settings, cancer vaccines as monotherapies have displayed limited success compared to other cancer immunotherapeutic treatments. Nanoscale formulations have the ability to increase the ... Read more

July 21, 2022July 21, 2022

Interleukin-7 regulates CD127 expression and promotes CD8 T cell activity in patients with primary cutaneous melanoma.

Melanoma Literature

Publication date: Jul 18, 2022 Interleukin (IL)-7 signaling through CD127 is impaired in lymphocytes in cancers and chronic infections, resulting in CD8 T cell exhaustion. The mechanisms underlying CD8 T ... Read more

July 21, 2022July 21, 2022

Interleukin-7 regulates CD127 expression and promotes CD8 T cell activity in patients with primary cutaneous melanoma.

Melanoma Literature

June 25, 2022June 25, 2022

Optimization of whole-cell vaccines with CpG/αOX40/cGAMP to strengthen the anti-tumor response of CD4 T cells in melanomas.

Melanoma Literature

Publication date: Jun 24, 2022 In this study, we developed a strategy for the prevention and therapy of melanoma using a whole-cell vaccine combined with a CpG/αOX40/cGAMP triple adjuvant. The ... Read more

July 14, 2022July 14, 2022

COVID-19 as a putative trigger of anti-MDA5-associated dermatomyositis with acute respiratory distress syndrome (ARDS) requiring lung transplantation, a case report.

Melanoma Literature

Publication date: Jul 13, 2022 Autoimmune disease following COVID-19 has been studied intensely since the beginning of the pandemic. Growing evidence indicates that SARS-CoV-2 infection, by virtue of molecular mimicry ... Read more