Search Results for: inflammation

March 17, 2019March 17, 2019

Intestinal microbiome as a novel therapeutic target for local and systemic inflammation.

Publication date: Mar 12, 2019 Recently, the pathogenesis of systemic inflammatory disease such as inflammatory bowel disease (IBD), multiple sclerosis (MS), systemic inflammatory arthritis, asthma, and non-alcoholic fatty liver disease ... Read more

March 16, 2019March 16, 2019

Effect of Teriflunomide and Dimethyl Fumarate on Cortical Atrophy and Leptomeningeal Inflammation in Multiple Sclerosis: A Retrospective, Observational, Case-Control Pilot Study.

Multiple Sclerosis Literature

Publication date: Mar 12, 2019 Background: Pathologic changes in cortical gray matter (GM) and leptomeninges contribute to disability worsening in patients with multiple sclerosis (MS), but there is little evidence ... Read more

March 13, 2019

Linking Mn2+, {alpha}-synuclein, and neuroinflammation

Parkinson's Disease News

Publication date: Mar 11, 2019 The scope of treatment applications is also broadening from chronic pain to include cerebral ischemia, dystonia, tremor, multiple sclerosis, Parkinson disease, neuropsychiatric disorders, memory, addiction, ... Read more

March 12, 2019March 12, 2019

Repurposed Therapies, New Compounds to Be Tested to Block Brain Inflammation in Parkinson’s

Parkinson's Disease News

Publication date: Mar 12, 2019 Researchers in Australia are planning to test therapies already being used in other inflammatory conditions, as well as new compounds, for their potential to block ... Read more

March 11, 2019March 11, 2019

Lupeol inhibits LPS-induced neuroinflammation in cerebellar cultures and induces neuroprotection associated to the modulation of astrocyte response and expression of neurotrophic and inflammatory factors.

Multiple Sclerosis Literature

Publication date: Mar 06, 2019 In the central nervous system (CNS), neuroinflammation, especially that modulated by the cell response of astrocytes and microglia, is associated with damage to neurons in ... Read more

March 5, 2019March 5, 2019

#ACTRIMS2019 – Cerebrospinal Fluid, Meninges Inflammation Profile Can Stratify MS Patients

Multiple Sclerosis News

Publication date: Mar 04, 2019 Recent studies suggested that extensive grey matter damage and more rapid disease progression were tied to high levels of inflammation in the meninges – the ... Read more

March 1, 2019March 1, 2019

Axonal and Myelin Neuroprotection by the Peptoid BN201 in Brain Inflammation.

Multiple Sclerosis Literature

Publication date: Feb 27, 2019 The development of neuroprotective therapies is a sought-after goal. By screening combinatorial chemical libraries using in vitro assays, we identified the small molecule BN201 that ... Read more

February 26, 2019February 26, 2019

Podocalyxin Helps Protect Blood-brain Barrier During Inflammation, Mouse Study Shows

Multiple Sclerosis News

Publication date: Feb 25, 2019 Podocalyxin, a protein found in cells lining the interior of blood vessels, is key for maintaining the integrity of the blood-brain barrier (BBB) in mice ... Read more

February 23, 2019February 23, 2019

High levels of serum soluble TWEAK are associated with neuroinflammation during multiple sclerosis.

Multiple Sclerosis Literature

Publication date: Feb 20, 2019 Inflammation and demyelination are the main processes in multiple sclerosis. Nevertheless, to date, blood biomarkers of inflammation are lacking. TWEAK, a transmembrane protein that belongs ... Read more

February 23, 2019February 23, 2019

Inflammation-induced hypoparathyroidism triggered by combination immune checkpoint blockade for melanoma.

Melanoma Literature

Publication date: Feb 21, 2019 Treatment with a combination of PD-1 and CTLA-4 targeted checkpoint inhibition has improved outcome of melanoma patients and led to durable remissions but is also ... Read more