Search Results for: inflammation

February 23, 2020

Neuroprotection by dihydrotestosterone in LPS-induced neuroinflammation.

Publication date: Feb 19, 2020 Microglia-induced neuroinflammation plays a vital role in the etiology and progression of neurodegenerative diseases, including Alzheimer’s disease, Parkinson’s disease and multiple sclerosis. The neuroprotective role ... Read more

February 23, 2020February 23, 2020

CD38 in Neurodegeneration and Neuroinflammation.

Parkinson's Disease Literature

Publication date: Feb 18, 2020 Neurodegenerative diseases are characterized by neuronal degeneration as well as neuroinflammation. While CD38 is strongly expressed in brain cells including neurons, astrocytes as well as ... Read more

February 20, 2020

A novel role of NLRP3-generated IL-1β in the acute-chronic transition of peripheral lipopolysaccharide-elicited neuroinflammation: implications for sepsis-associated neurodegeneration.

Parkinson's Disease Literature

Publication date: Feb 18, 2020 Sepsis-associated acute brain inflammation, if unresolved, may cause chronic neuroinflammation and resultant neurodegenerative diseases. However, little is known how the transition from acute to chronic ... Read more

February 15, 2020February 15, 2020

Association of poorer dietary quality and higher dietary inflammation with greater symptom severity in depressed individuals with appetite loss.

Major Depressive Disorder Literature

Publication date: Feb 15, 2020 Major depressive disorder (MDD) is the leading cause of years lived with disability; however, little is known about its etiology to inform treatment. For a ... Read more

February 14, 2020February 14, 2020

MAFG-driven astrocytes promote CNS inflammation.

Multiple Sclerosis Literature

Publication date: Feb 12, 2020 Multiple sclerosis is a chronic inflammatory disease of the CNS. Astrocytes contribute to the pathogenesis of multiple sclerosis, but little is known about the heterogeneity ... Read more

February 13, 2020February 13, 2020

Parkinson’s driven by inflammation, genetics and the environment

Parkinson's Disease News

Publication date: Feb 12, 2020 Standaert directs the Morris K. Udall Center of Excellence in Parkinson’s Disease Research, one of eight such centers funded by the National Institute of Neurological ... Read more

February 7, 2020February 7, 2020

Positive allosteric modulation of indoleamine 2,3-dioxygenase 1 restrains neuroinflammation.

Multiple Sclerosis Literature

Publication date: Feb 05, 2020 l-tryptophan (Trp), an essential amino acid for mammals, is the precursor of a wide array of immunomodulatory metabolites produced by the kynurenine and serotonin pathways. ... Read more

February 6, 2020February 6, 2020

Inflammation of the choroid plexus in progressive multiple sclerosis: accumulation of granulocytes and T cells.

Multiple Sclerosis Literature

Publication date: Feb 03, 2020 The choroid plexus (CP) is strategically located between the peripheral blood and the cerebrospinal fluid, and is involved in the regulation of central nervous system ... Read more

February 4, 2020February 4, 2020

Parkinson’s driven by inflammation, genetics, and the environment

Parkinson's Disease News

Publication date: Feb 03, 2020 -The reality is that today, we still don’t have a treatment that slows or alters the progression of Parkinson’s disease,” said David Standaert, M. D., ... Read more

February 1, 2020February 1, 2020

Interpersonal life stress, inflammation, and depression in adolescence: Testing Social Signal Transduction Theory of Depression.

Major Depressive Disorder Literature

Publication date: Feb 01, 2020 Depression rates increase markedly for girls across the adolescent transition, but the social-environmental and biological processes underlying this phenomenon remain unclear. To address this issue, ... Read more