Search Results for: inflammation

March 21, 2020March 21, 2020

The suppressive effect of dabrafenib, a therapeutic agent for metastatic melanoma, in IgE-mediated allergic inflammation.

Melanoma Literature

Publication date: Mar 17, 2020 The functional inhibition of mast cells, which serve as a key effector cells in allergic reactions may be a specific target for treating immunoglobulin (Ig)E-mediated ... Read more

March 18, 2020March 18, 2020

RIC3, the cholinergic anti-inflammatory pathway, and neuroinflammation.

Multiple Sclerosis Literature

Publication date: Mar 13, 2020 Nicotinic acetylcholine receptors (nAChRs) are ligand-gated ion channels having many functions including inflammation control, as part of the cholinergic anti-inflammatory pathway. Genome wide association studies ... Read more

March 18, 2020March 18, 2020

Bile acid metabolism is altered in multiple sclerosis and supplementation ameliorates neuroinflammation.

Multiple Sclerosis Literature

Publication date: Mar 17, 2020 Multiple sclerosis (MS) is an inflammatory demyelinating disorder of the CNS. Bile acids are cholesterol metabolites that can signal through receptors on cells throughout the ... Read more

March 18, 2020

Lipoprotein profiling in early multiple sclerosis patients: effect of chronic inflammation?

Multiple Sclerosis Literature

Publication date: Mar 17, 2020 Inflammatory cytokines contribute to proatherogenic changes in lipid metabolism by reduction of HDL-cholesterol (HDL-C) levels, impairment of its antiinflammatory and antioxidant functions. Therefore, the protective ... Read more

March 17, 2020March 17, 2020

Cambridge study adds evidence linking brain inflammation with dementia

Huntington's Disease News

Publication date: Mar 17, 2020 Over the last couple of decades researchers have started implicating inflammation as playing a role in a number of conditions not traditionally thought of as ... Read more

March 16, 2020March 16, 2020

RNA-Binding Protein HuR Promotes Th17 Cell Differentiation and Can Be Targeted to Reduce Autoimmune Neuroinflammation.

Multiple Sclerosis Literature

Publication date: Mar 13, 2020 Dysregulated Th17 cell differentiation is associated with autoimmune diseases such as multiple sclerosis, which has no curative treatment. Understanding the molecular mechanisms of regulating Th17 ... Read more

March 16, 2020March 16, 2020

Sema4A is implicated in the acceleration of Th17 cell-mediated neuroinflammation in the effector phase.

Multiple Sclerosis Literature

Publication date: Mar 13, 2020 Sema4A is a regulator of helper T cell (Th) activation and differentiation in the priming phase, which plays an important role in the pathogenesis of ... Read more

March 14, 2020March 14, 2020

Anti-oxidant and anti-inflammatory effects of auraptene on phytohemagglutinin (PHA)-induced inflammation in human lymphocytes.

Multiple Sclerosis Literature

Publication date: Mar 12, 2020 Inflammation is characterized as a defensive response of our body against endogenous or exogenous stimuli. Chronic inflammation and oxidative stress play an important role in ... Read more

March 14, 2020March 14, 2020

Neuroinflammation: an overview of neurodegenerative and metabolic diseases and of biotechnological studies.

Multiple Sclerosis Literature

Publication date: Mar 09, 2020 Neuroinflammation is an important factor contributing to cognitive impairment and neurodegenerative diseases, including Alzheimer’s disease (AD), Parkinson’s disease (PD), Amyotrophic lateral sclerosis (ALS), ischemic injury, ... Read more

March 10, 2020March 10, 2020

Angiopoietin-2 blockade ameliorates autoimmune neuroinflammation by inhibiting leukocyte recruitment into the CNS.

Multiple Sclerosis Literature

Publication date: Mar 09, 2020 Angiopoietin-2 (Ang2), a ligand of the endothelial Tie2 tyrosine kinase, is involved in vascular inflammation and leakage in critically ill patients. However, the role of ... Read more