Search Results for: malignancy

November 22, 2019November 22, 2019

The potential for malignancy from atopic disorders and allergic inflammation: A systematic review and meta-analysis.

Melanoma Literature

Publication date: Nov 19, 2019 While chronic inflammation is a well-established risk factor for malignancy, studies evaluating the relationship between allergic inflammation and cancer have revealed conflicting results. Here, we ... Read more

November 1, 2019November 1, 2019

Immunomodulatory aspects in the progression and treatment of oral malignancy.

Melanoma Literature

Publication date: Nov 01, 2019 Inflammation substantially affects the risk of oral malignancy. Pro-inflammatory cytokine, interferon (IFN)-γ, confers anti-tumor activity using several different mechanisms. Conversely, higher expression of interleukin (IL)-17 ... Read more

October 18, 2019October 18, 2019

FGFR3 promotes the growth and malignancy of melanoma by influencing EMT and the phosphorylation of ERK, AKT, and EGFR.

Melanoma Literature

Publication date: Oct 16, 2019 Overexpression of fibroblast growth factor receptor 3 (FGFR3) has been linked to tumor progression in many types of cancer. The role of FGFR3 in melanoma ... Read more

October 10, 2019October 10, 2019

Maintaining Quality of Life: Electrochemotherapy for Palliative Periorbital Malignancy.

Melanoma Literature

Publication date: Oct 04, 2019 Electrochemotherapy has been used successfully for treatment of recurrent head and neck skin cancers and skin metastasis. It combines both electroporation and chemotherapy. The authors ... Read more

August 31, 2019August 31, 2019

Management of congenital melanocytic nevi in the plastic surgery clinic: Families’ expectations and their persistent concern about malignancy.

Melanoma Literature

Publication date: Aug 29, 2019 Children with congenital melanocytic nevi (CMN) were historically managed with surgical removal to lower the risk of malignant transformation. The evolving literature over the last ... Read more

August 10, 2019August 10, 2019

HLA Expression in Uveal Melanoma: An Indicator of Malignancy and a Modifiable Immunological Target.

Melanoma Literature

Publication date: Aug 07, 2019 Uveal melanoma (UM) is the most common primary intraocular malignancy in adults, and gives rise to metastases in 50% of cases. The presence of an ... Read more

July 19, 2019July 19, 2019

Automated identification of malignancy in whole-slide pathological images: identification of eyelid malignant melanoma in gigapixel pathological slides using deep learning.

Melanoma Literature

Publication date: Jul 13, 2019 To develop a deep learning system (DLS) that can automatically detect malignant melanoma (MM) in the eyelid from histopathological sections with colossal information density. Setting: ... Read more

June 8, 2019June 8, 2019

Embryonic stem cell microenvironment suppresses the malignancy of cutaneous melanoma cells by down-regulating PI3K/AKT pathway.

Melanoma Literature

Publication date: Jun 07, 2019 Malignant cancer cells engage in a dynamic reciprocity with the tumor microenvironment (TME) that promotes tumor growth, development, and resistance to therapy. Early embryonic blastocyst ... Read more

March 1, 2019March 1, 2019

High Throughput Functional Screening for Precision Medicine Approaches in Hematologic Malignancy

Precision Medicine Media

Publication date: Feb 28, 2019 Everyone’s cancer is unique, with a different pattern of gene mutations. But for a long time, each type of cancer was treated in a similar ... Read more

February 16, 2019February 16, 2019

Retrospective single-center study evaluating clinical and dermoscopic features of longitudinal melanonychia, ABCDEF criteria, and risk of malignancy.

Melanoma Literature

Publication date: Feb 11, 2019 Longitudinal melanonychia (LM) is a common finding in clinical practice; however, it has a broad differential diagnosis, including subungual melanoma (SUM), which can be difficult ... Read more