Publication date: Mar 25, 2020 The purpose of this article is to provide a primer for radiologists outlining the modern systemic therapies used in melanoma brain metastases, including tyrosine kinase ... Read more

Publication date: Mar 27, 2020 Anti-PD1 immunotherapy has shown a sustainable clinical activity in patients with metastatic melanoma. However, strong predictive factors of the long-term response or risk of relapse ... Read more

Publication date: Jul 14, 2019 The increased PD-L1 expression induces poorer prognosis in melanoma. The small molecule inhibitors of PD-1/PD-L1 pathways have been an encouraging drug development strategy because of ... Read more

Publication date: Mar 24, 2020 Natural killer (NK) cells provide a natural defense against MHC-I-negative tumors, such as melanoma. Donor lymphocyte infusion (DLI) containing NK cells, a form of adoptive ... Read more

Publication date: Mar 24, 2020 Efficient plasmonic photothermal therapies (PPTTs) using non-harmful pulse laser irradiation at the near-infrared (NIR) are a highly sought goal in nanomedicine. These therapies rely on ... Read more

Publication date: Mar 24, 2020 Malignant melanoma is among the most aggressive skin cancers and it has among the highest metastatic potentials. Although surgery to remove the primary tumor is ... Read more

Publication date: Mar 25, 2020 Olteanu, C., Scope, A., Steinberg-Silman, Y., Ziv, M., Shear, N.H., Dodiuk-Gad, R.P., and Markel, G. Vemurafenib-induced DRESS/DIHS resulting in spontaneous melanoma regression: an immunological reaction ... Read more

Publication date: Mar 25, 2020 Men and women develop melanoma at different rates on different body sites, with variation across countries, but explanations for these disparities remain elusive. To test ... Read more

Publication date: Mar 25, 2020 Growing evidence supports that isothiocyanates exert a wide range of bioactivities amongst of which is their capacity to interact with the epigenetic machinery in various ... Read more

Publication date: Mar 26, 2020 Melanoma is a poor immunogenic cancer and many treatment strategies have been used to enhance specific or nonspecific immunity against it. Dendritic cell (DC)-based cancer ... Read more