Search Results for: melanoma

July 17, 2019July 17, 2019

Safety and Efficacy of Sonocloud Device Combined With Nivolumab in Brain Metastases From Patients With Melanoma

Melanoma News

Publication date: Jul 16, 2019 Anti PD-1 monoclonal antibodies (nivolumab and pembrolizumab) alone or in association with antiCTLA4 (Ipilimumab) are established as indisputable treatment of metastatic melanoma, with unprecedented overall ... Read more

July 17, 2019July 17, 2019

Pilot Trial of Neoadjuvant Atezolizumab in Cutaneous Melanoma

Melanoma News

Publication date: Jul 16, 2019 The purpose of this research study is to see whether using atezolizumab before surgery is safe and does not cause side effects that delay surgery ... Read more

July 17, 2019July 17, 2019

Pilot Trial of Neoadjuvant Atezolizumab in Cutaneous Melanoma

Melanoma News

Publication date: Jul 16, 2019 The purpose of this research study is to see whether using atezolizumab before surgery is safe and does not cause side effects that delay surgery ... Read more

July 17, 2019July 17, 2019

Having a close relative with melanoma could raise your risk of it by 74 per cent

Melanoma News

Publication date: Jul 16, 2019 Researchers from Indiana University studied the medical records of more than 200,000 people and found the risk of getting squamous or basal cell carcinoma also ... Read more

July 17, 2019July 17, 2019

Syngeneic B16-F1 cells are more efficient than allogeneic Cloudman cells as antigen source in DC-based vaccination in the B16-F1 murine melanoma model.

Melanoma Literature

Publication date: Jul 13, 2019 A major obstacle to obtaining relevant results in cancer vaccination has been the lack of identification of immunogenic antigens. Dendritic cell (DC)-based cancer vaccines used ... Read more

July 17, 2019July 17, 2019

Immunomodulatory germline variation associated with the development of multiple primary melanoma (MPM).

Melanoma Literature

Publication date: Jul 15, 2019 Multiple primary melanoma (MPM) has been associated with a higher 10-year mortality risk compared to patients with single primary melanoma (SPM). Given that 3-8% of ... Read more

July 17, 2019July 17, 2019

Extracellular acidosis triggers a senescence-like phenotype in human melanoma cells.

Melanoma Literature

Publication date: Jul 16, 2019 Acidosis of the tumor microenvironment is a characteristic of solid tumors such as malignant melanoma. Main causes of the extracellular acidification are metabolic alterations in ... Read more

July 17, 2019July 17, 2019

External validation of a prognostic model to predict survival of patients with sentinel node-negative melanoma.

Melanoma Literature

Publication date: Jul 16, 2019 Identifying patients with sentinel node-negative melanoma at high risk of recurrence or death is important. The European Organisation for Research and Treatment of Cancer (EORTC) ... Read more

July 17, 2019July 17, 2019

Biophysical and biochemical characteristics as complementary indicators of melanoma progression.

Melanoma Literature

Publication date: Jul 16, 2019 The multi-step character of cancer progression makes it difficult to define a unique biomarker of the disease. Interdisciplinary approaches, combining various complimentary techniques, especially those ... Read more

July 17, 2019July 17, 2019

Glutathione peroxidase 3 (GPX3) suppresses the growth of melanoma cells through reactive oxygen species (ROS)-dependent stabilization of hypoxia-inducible factor 1-α and 2-α.

Melanoma Literature

Publication date: Jul 16, 2019 In this study, we aimed to explore the mechanism of glutathione peroxidase 3 (GPX3) in the growth of malignant melanoma (MM) cells by hypoxia-inducible factor-1α ... Read more