Search Results for: metastasis

March 22, 2025March 22, 2025

Surveillance for Metastasis in Low-Risk Uveal Melanoma Patients: Need for Optimization.

Melanoma Literature

Publication date: Mar 19, 2025 To evaluate the effectiveness of surveillance protocols utilizing hepatic ultrasonography (US) at 6-month intervals to detect metastasis and determine its impact on overall survival (OS) ... Read more

March 22, 2025March 22, 2025

Highly infiltrative brain metastasis of RET mutant lung primary: Morphometric assessment and molecular review.

Melanoma Literature

Publication date: Mar 21, 2025 Histologic differentiation between primary brain tumors and metastases is an important aspect of intraoperative consultation. We present a case of metastatic carcinoma with microscopic features ... Read more

March 20, 2025March 20, 2025

Artificial Intelligence and Convolutional Neural Networks-Driven Detection of Micro and Macro Metastasis of Cutaneous Melanoma to the Lymph Nodes.

Melanoma Literature

Publication date: Mar 19, 2025 Lymph node (LN) assessment is a critical component in the staging and management of cutaneous melanoma. Traditional histopathological evaluation, supported by immunohistochemical staining, is the ... Read more

March 19, 2025March 19, 2025

Inclusion of ΑVβ3 integrin into extracellular vesicles in a caveolin-1 tyrosine-14- phosphorylation dependent manner and subsequent transfer to recipient melanoma cells promotes migration, invasion and metastasis.

Melanoma Literature

Publication date: Mar 17, 2025 Caveolin-1 (CAV1) is a membrane protein that promotes migration, invasion and metastasis of cancer cells when phosphorylated on tyrosine-14 (Y14) by a cell intrinsic mechanism ... Read more

March 14, 2025March 14, 2025

Targeting brain macrophages: NF-κB as a therapeutic gateway in melanoma brain metastasis.

Melanoma Literature

Publication date: Mar 10, 2025 Melanoma brain metastasis (MBM) is associated with poor prognosis. In this issue of Cancer Cell, Rodriguez-Baena et al. identify nuclear factor _705B (NF-_705B) (Rela) as ... Read more

March 14, 2025March 14, 2025

Targeting brain macrophages: NF-κB as a therapeutic gateway in melanoma brain metastasis.

Melanoma Literature

March 12, 2025March 12, 2025

Identification of Predictive Factors for the Development of In-Transit Metastasis in Patients with Melanoma.

Melanoma Literature

Publication date: Mar 10, 2025 In patients with melanoma, in-transit metastasis (ITM) can develop. This study aimed to identify the risk for a first recurrence of ITM and associated predictive ... Read more

March 12, 2025March 12, 2025

Identification of Predictive Factors for the Development of In-Transit Metastasis in Patients with Melanoma.

Melanoma Literature

March 10, 2025March 10, 2025

MDA-9/Syntenin as a therapeutic cancer metastasis target: current molecular and preclinical understanding.

Melanoma Literature

Publication date: Mar 08, 2025 Metastasis is a principal cause of patient morbidity and death from solid cancers with current therapies being inadequate. Detailed genomic analyses document mutational differences between ... Read more

March 10, 2025March 10, 2025

MDA-9/Syntenin as a therapeutic cancer metastasis target: current molecular and preclinical understanding.

Melanoma Literature