Search Results for: neurodegenerative diseases

March 12, 2019March 12, 2019

Molecular chaperones biochemistry and role in neurodegenerative diseases.

Publication date: Mar 07, 2019 Many neurodegenerative diseases including Parkinson’s disease, Alzheimer’s disease, Prion’s disease, polyQ and Huntington’s disease share abnormal folding of potentially cytotoxic protein species associated with degeneration ... Read more

March 12, 2019March 12, 2019

Positron emission tomography neuroimaging in neurodegenerative diseases: Alzheimer’s disease, Parkinson’s disease, and amyotrophic lateral sclerosis.

Parkinson's Disease Literature

Publication date: Mar 11, 2019 Neurodegenerative diseases are a growing problem of ageing societies. Their insidious onset, and the lack of reliable biomarkers, result in significant diagnosis delays. This article ... Read more

March 8, 2019March 8, 2019

Missing in Action: Dysfunctional RNA Metabolism in Oligodendroglial Cells as a Contributor to Neurodegenerative Diseases?

Multiple Sclerosis Literature

Publication date: Mar 06, 2019 The formation of myelin around axons by oligodendrocytes (OL) poses an enormous synthetic and energy challenge for the glial cell. Local translation of transcripts, including ... Read more

February 16, 2019February 16, 2019

Measuring network disruption in neurodegenerative diseases: New approaches using signal analysis.

Multiple Sclerosis Literature

Publication date: Feb 13, 2019 Advanced neuroimaging has increased understanding of the pathogenesis and spread of disease, and offered new therapeutic targets. MRI and positron emission tomography have shown that ... Read more

February 1, 2019February 1, 2019

A cross-brain regions study of ANK1 DNA methylation in different neurodegenerative diseases.

Huntington's Disease Literature

Publication date: Feb 01, 2019 Recent epigenome-wide association studies in Alzheimer’s disease have highlighted consistent robust neuropathology-associated DNA hypermethylation of the ankyrin 1 (ANK1) gene in the cortex. The extent ... Read more

January 10, 2019January 10, 2019

Nuclear Receptors as Therapeutic Targets for Neurodegenerative Diseases: Lost in Translation.

Huntington's Disease Literature

Publication date: Jan 06, 2019 Neurodegenerative diseases are characterized by a progressive loss of neurons that leads to a broad range of disabilities, including severe cognitive decline and motor impairment, ... Read more

January 6, 2019January 6, 2019

Antisense Transcription in Loci Associated to Hereditary Neurodegenerative Diseases.

Huntington's Disease Literature

Publication date: Jan 04, 2019 Natural antisense transcripts are common features of mammalian genes providing additional regulatory layers of gene expression. A comprehensive description of antisense transcription in loci associated ... Read more

December 28, 2018December 28, 2018

Neuritosis Study Opens Door for Potential New Therapies for Neurodegenerative Diseases

Huntington's Disease News

Publication date: Dec 28, 2018 Scientists from the University of Pittsburgh School of Medicine, using animal models and nerve cells grown in the lab, have described a new mechanism dubbed ... Read more

December 15, 2018December 15, 2018

Gene Therapy for Neurodegenerative Diseases.

Huntington's Disease Literature

Publication date: Dec 12, 2018 Gene therapy has the potential to provide therapeutic benefit to millions of people with neurodegenerative diseases through several means, including direct correction of pathogenic mechanisms, ... Read more

December 6, 2018December 6, 2018

Dynamin-related protein 1: A critical protein in the pathogenesis of neural system dysfunctions and neurodegenerative diseases.

Huntington's Disease Literature

Publication date: Dec 04, 2018 Mitochondria play a key role in the maintenance of neuronal function by continuously providing energy. Here, we will give a detailed review about the recent ... Read more