Search Results for: nucleic acid

January 16, 2025January 16, 2025

Multiplex Digital Nucleic Acid Analysis by a LAMP-Argonaute Coupling Assay via a Parallel Droplet Fusion SlipChip.

Publication date: Jan 14, 2025 Multiplex digital nucleic acid analysis (NAA) allows the precise quantification of multiple target nucleic acids with single-molecule sensitivity, making it highly appealing for life science ... Read more

January 16, 2025January 16, 2025

Rapid and comprehensive detection of viral antibodies and nucleic acids via an acoustofluidic integrated molecular diagnostics chip: AIMDx.

Coronavirus Literature

Publication date: Jan 17, 2025 Precise and rapid disease detection is critical for controlling infectious diseases like COVID-19. Current technologies struggle to simultaneously identify viral RNAs and host immune antibodies ... Read more

January 11, 2025January 11, 2025

Development of a portable multi-step microfluidic device for point-of-care nucleic acid diagnostics.

Coronavirus Literature

Publication date: Jan 22, 2025 The COVID-19 pandemic has significantly affected global health, economies, and societies, and highlighted the urgent need for rapid, sensitive, affordable, and portable diagnostic devices for ... Read more

January 10, 2025January 10, 2025

Exploiting the Potential of Spherical PAM Antenna for Enhanced CRISPR-Cas12a: A Paradigm Shift toward a Universal Amplification-Free Nucleic Acid Test Platform.

Tuberculosis Literature

Publication date: Jan 09, 2025 The CRISPR-Cas12a system has shown tremendous potential for developing efficient biosensors. Albeit important, current CRISPR-Cas system-based diagnostic technologies (CRISPR-DX) highly rely on an additional preamplification ... Read more

January 5, 2025January 5, 2025

Short-Time Preamplification-Assisted One-Pot CRISPR Nucleic Acid Detection Method with Portable Self-Heating Equipment for Point-of-Care Diagnosis.

Coronavirus Literature

Publication date: Jan 04, 2025 Infectious diseases, especially respiratory infections, have been significant threats to human health. Therefore, it is essential to develop rapid, portable, and highly sensitive diagnostic methods ... Read more

January 4, 2025January 4, 2025

Viral nucleic acid load in the milk of lactating mothers with COVID-19 and the prognosis of infants.

Coronavirus Literature

Publication date: Jan 03, 2025 The global spread of the novel coronavirus disease 2019, caused by SARS-CoV-2 virus, impacts individuals of all age groups, including lactating women and children. Concerns ... Read more

December 29, 2024December 29, 2024

Nucleic Acid Lateral Flow Assay Implemented with Isothermal Gene Amplification of SARS-CoV-2 RNA.

Coronavirus Literature

Publication date: Dec 01, 2024 We developed a rapid and sensitive diagnostic platform that integrates isothermal viral gene amplification with a nucleic acid lateral flow assay (NALFA) to detect SARS-CoV-2 ... Read more

December 22, 2024December 22, 2024

Targeting modulation of intestinal flora through oral route by an antimicrobial nucleic acid-loaded exosome-like nanovesicles to improve Parkinson’s disease.

Parkinson's Disease Literature

Publication date: Dec 30, 2024 Parkinson’s disease (PD) is one of the most prevalent neurodegenerative diseases. It is usually accompanied by motor and non-motor symptoms that seriously threaten the health ... Read more

December 20, 2024December 20, 2024

Clinical characteristics and prediction model of re-positive nucleic acid tests among Omicron infections by machine learning: a real-world study of 35,488 cases.

Coronavirus Literature

Publication date: Dec 18, 2024 During the Omicron BA. 2 variant outbreak in Shanghai, China, from April to May 2022, PCR nucleic acid test re-positivity (TR) occurred frequently, yet the ... Read more

December 18, 2024December 18, 2024

Microfluidic Chip-based Enrichment and Nucleic Acid Extraction for Quantitative Detection of Mycobacterium Smegmatis in Aerosols.

Tuberculosis Literature

Publication date: Dec 17, 2024 Tuberculosis (TB) is ranked as the third most prevalent infectious disease globally. Early detection and treatment are crucial for effective management. Conventional diagnostic methods primarily ... Read more