Search Results for: organ

October 13, 2024October 13, 2024

Gestational exposure to organophosphate esters and autism spectrum disorder and other non-typical development in a cohort with elevated familial likelihood.

Autism Literature

Publication date: Oct 10, 2024 Gestational exposure to organophosphate esters (OPEs) is known to affect offspring neurodevelopment in animal studies. However, epidemiological evidence is inconsistent. Participants were 277 mother-child pairs ... Read more

October 13, 2024October 13, 2024

Neuronal lineage tracing from progenitors in human cortical organoids reveals mechanisms of neuronal production, diversity, and disease.

Autism Literature

Publication date: Oct 11, 2024 The contribution of progenitor subtypes to generating the billions of neurons produced during human cortical neurogenesis is not well understood. We developed the cortical organoid ... Read more

October 11, 2024October 11, 2024

Investigation of severe acute respiratory syndrome coronavirus 2 infection status in solid organ transplant recipients treated with tixagevimab/cilgavimab.

Coronavirus Literature

Publication date: Dec 01, 2024 Tixagevimab and cilgavimab (T/C) are neutralizing antibodies against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that can be used to prevent SARS-CoV-2 infection in solid ... Read more

October 10, 2024October 10, 2024

Estimating Long-Term Survivorship Rates Among Patients With Resected Stage III/IV Melanoma: Analyses From CheckMate 238 and European Organization for Research and Treatment of Cancer 18071 Trials.

Melanoma Literature

Publication date: Oct 08, 2024 Standard-of-care treatments for patients with resected stage III/IV melanoma include the immuno-oncology (IO) agents nivolumab (NIVO) and ipilimumab (IPI). This study used mixture cure models ... Read more

October 9, 2024October 9, 2024

Impact of Lipid Tail Length on the Organ Selectivity of mRNA-Lipid Nanoparticles.

Coronavirus Literature

Publication date: Oct 07, 2024 The delivery of mRNA molecules to organs beyond the liver is valuable for therapeutic applications. Functionalized lipid nanoparticles (LNPs) using exogenous mechanisms can regulate in ... Read more

October 9, 2024October 9, 2024