Search Results for: pathophysiology

Interplay of NMDAR and AMPAR in the Pathophysiology of Alzheimer’s, Parkinson, ALS, Huntington’s, and Epilepsy: An Update in Therapeutic Perspective.

Interplay of NMDAR and AMPAR in the Pathophysiology of Alzheimer’s, Parkinson, ALS, Huntington’s, and Epilepsy: An Update in Therapeutic Perspective.

Huntington's Disease Literature
Publication date: May 16, 2026 Glutamate-mediated excitotoxicity is a central driver of neurodegeneration and represents a shared pathogenic mechanism across neurodegenerative diseases and epilepsy, with N-methyl-D-aspartate receptors (NMDARs) and α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic ... Read more