Search Results for: tics

March 24, 2025March 24, 2025

Exosome-based therapeutics: Advancing drug delivery for neurodegenerative diseases.

Publication date: Mar 21, 2025 Neurodegenerative disorders include Parkinson’s disease, spinal cord injury, multiple sclerosis and Alzheimer’s disease, cause gradual neuronal loss, protein misfolding, and accumulation, resulting in severe cognitive ... Read more

March 24, 2025March 24, 2025

Clinical development of immuno-oncology therapeutics.

Melanoma Literature

Publication date: May 01, 2025 Immuno-oncology (IO) is one of the fastest growing therapeutic areas within oncology. IO agents work indirectly via the host’s adaptive and innate immune system to ... Read more

March 23, 2025March 23, 2025

Pharmacokinetics and Safety Profile of SNS812, a First in Human Fully Modified siRNA Targeting Wide-Spectrum SARS-CoV-2, in Healthy Subjects.

Coronavirus Literature

Publication date: Mar 01, 2025 Severe acute respiratory syndrome caused by the coronavirus (SARS-CoV-2) in the COVID-19 pandemic has highlighted the need for effective treatments, as rapid viral mutations complicate ... Read more

March 23, 2025March 23, 2025

Prevalence and Clinical Characteristics of the LRRK2 p.L1795F Variant in Central Europeans with Early-Onset and Familial Parkinson’s Disease.

Parkinson's Disease Literature

Publication date: Mar 22, 2025 Leucine-rich repeat kinase 2 (LRRK2) p. L1795F variant was proposed as a genetic risk factor for Parkinson’s disease (PD). However, its prevalence, phenotype, and origin ... Read more

March 23, 2025March 23, 2025

The characteristics of anhedonia in depression: a review from a clinically oriented perspective.

Major Depressive Disorder Literature

Publication date: Mar 21, 2025 Anhedonia, as one of the core symptoms of major depressive disorder (MDD), has been regarded as a potential endophenotype of the disease. Multiple studies have ... Read more

March 22, 2025March 22, 2025

Microplastics and chemical additives from disposable face masks: Environmental, human health and behavioural impacts.

Coronavirus Literature

Publication date: Mar 20, 2025 Microplastic (MP) pollution has emerged as a major environmental issue with significant health implications. Synthetic face masks (FMs) have been identified as a substantial source ... Read more

March 22, 2025March 22, 2025

Oligonucleotide-Based Therapeutics for Neurodegenerative Disorders: Focus on Antisense Oligonucleotides.

Huntington's Disease Literature

Publication date: Mar 19, 2025 Antisense oligonucleotides (ASOs) specifically bind to target RNA sequences and regulate protein expression through various mechanisms. ASOs are a promising therapeutic approach for treating neurodegenerative ... Read more

March 22, 2025March 22, 2025

Genetics of SSRI Antidepressant Use and Relationship to Psychiatric and Medical Traits

Major Depressive Disorder News

Publication date: Mar 20, 2025 Antidepressants are among the most-prescribed drugs worldwide, and selective serotonin reuptake inhibitors (SSRIs) are among the most prescribed antidepressants, most commonly used for major depression. ... Read more

March 22, 2025March 22, 2025

COVID-19 in Norwegian ICUs 2020-2023: Patient characteristics, management, and outcomes-A nationwide prospective observational study.

Coronavirus Literature

Publication date: Apr 01, 2025 During the COVID-19 pandemic, Norway experienced successive waves of hospital and intensive care unit (ICU) admissions, each with distinct characteristics, including patient demographics, medical therapies, ... Read more

March 22, 2025March 22, 2025

Epidemiological and molecular characteristics of human parainfluenza virus in southern China during 2016-2020.

Coronavirus Literature

Publication date: Mar 18, 2025 Human parainfluenza viruses (HPIV) are common viral pathogens in acute respiratory infection (ARI). We aimed to describe the epidemiological and molecular characteristics of HPIV from ... Read more