Search Results for: uncertainty

March 25, 2020March 25, 2020

Blinded sample size reestimation for negative binomial regression with baseline adjustment.

Publication date: Mar 23, 2020 In randomized clinical trials, it is standard to include baseline variables in the primary analysis as covariates, as it is recommended by international guidelines. For ... Read more

March 24, 2020March 24, 2020

Emerald Health Pharmaceuticals’ Lead Product Candidate Determined Not to be a Controlled Substance in Canada

Huntington's Disease News

Publication date: Mar 24, 2020 The same previous designation by the US Drug Enforcement Administration alleviates the typical complexities associated with developing controlled substances throughout North America SAN DIEGO, CA, ... Read more

March 23, 2020

Beyond the hype of big data and artificial intelligence: building foundations for knowledge and wisdom.

Precision Medicine Literature

Publication date: Jul 17, 2019 Big data, coupled with the use of advanced analytical approaches, such as artificial intelligence (AI), have the potential to improve medical outcomes and population health. ... Read more

March 23, 2020March 23, 2020

Investigating the use of data-driven artificial intelligence in computerised decision support systems for health and social care: A systematic review.

Precision Medicine Literature

Publication date: Jan 22, 2020 There is growing interest in the potential of artificial intelligence to support decision-making in health and social care settings. There is, however, currently limited evidence ... Read more

March 23, 2020March 23, 2020

Machine learning analysis of motor evoked potential time series to predict disability progression in multiple sclerosis.

Multiple Sclerosis Literature

Publication date: Mar 21, 2020 Evoked potentials (EPs) are a measure of the conductivity of the central nervous system. They are used to monitor disease progression of multiple sclerosis patients. ... Read more

March 21, 2020March 21, 2020

Considering patient clinical history impacts performance of machine learning models in predicting course of multiple sclerosis.

Multiple Sclerosis Literature

Publication date: Oct 09, 2019 Multiple Sclerosis (MS) progresses at an unpredictable rate, but predictions on the disease course in each patient would be extremely useful to tailor therapy to ... Read more

March 20, 2020

Cost-Effectiveness of Subsequent Whole-Brain Radiotherapy or Hippocampal-Avoidant Whole-Brain Radiotherapy Versus Stereotactic Radiosurgery or Surgery Alone for Treatment of Melanoma Brain Metastases.

Melanoma Literature

Publication date: Mar 11, 2020 A randomized phase III trial comparing whole-brain radiotherapy (WBRT) to observation following definitive local treatment of intracranial melanoma metastases with neurosurgery and/or stereotactic surgery (SRS) ... Read more

March 18, 2020

Experiences of adjustment to secondary progressive multiple sclerosis: a meta-ethnographic systematic review.

Multiple Sclerosis Literature

Publication date: Mar 14, 2020 Purpose: To provide an overview of the experiences and needs of patients adjusting to life after receiving a diagnosis of secondary progressive multiple sclerosis (SPMS).Method: ... Read more

March 18, 2020

Diagnostic profiles for precision medicine in systemic sclerosis; stepping forward from single biomarkers towards pathophysiological panels.

Precision Medicine Literature

Publication date: Mar 12, 2020 Systemic sclerosis (SSc) is an autoimmune disease which is characterized by vasculopathy, tissue fibrosis and activation of the innate and adaptive immune system. Clinical features ... Read more

March 10, 2020March 10, 2020

Neurocognitive and emotional status after one-year of mindfulness-based intervention in patients with relapsing-remitting multiple sclerosis.

Multiple Sclerosis Literature

Publication date: Mar 09, 2020 Multiple sclerosis (MS) is the most common disabling neurological disease among young adults. The diagnosis of this disease usually leads to uncertainty, stress, and anxiety, ... Read more