Publication date: Jul 04, 2020 Preliminary evidence has documented functional connectivity during the cognitive task in Autism Spectrum Disorder (ASD). However, evidence of effective neural connectivity with respect to information ... Read more

Publication date: Jul 05, 2020 Autism spectrum disorders (ASD) are highly heritable and are characterized by deficits in social communication and restricted and repetitive behaviors. Twin studies on phenotypic subdomains ... Read more

Publication date: Jul 06, 2020 For preschool children with autism, individual (one-to-one) behavioral interventions are among the best-tested treatments. However, they are rarely used in special education preschools. We observed ... Read more

Publication date: Jul 06, 2020 This study reports the results of a randomized trial for preverbal preschoolers with autism that demonstrates the effects of multiple intervention strategies including caregiver training. ... Read more

Publication date: Jul 01, 2020 The social approach and social novelty tests utilizing the three-chamber apparatus are widely accepted to measure social behavior of rodents. The LABORAS system offers a ... Read more

Publication date: Jul 01, 2020 There is an emerging body of evidence associating children having autism spectrum disorder (ASD) with gastrointestinal (GI) symptoms, such as abdominal pain, chronic diarrhea, constipation, ... Read more

Publication date: Jul 01, 2020 Homozygous mutations of ALDH5A1 have been reportedly associated with Succinic semialdehyde dehydrogenase deficiency (SSADHD) that affects gamma-aminobutyric acid (GABA) catabolism and evinces a wide range ... Read more

Publication date: Jul 02, 2020 Studying social modulation of cognitive processes holds much promise for illuminating how, where, when and why social factors influence how we perceive and act in ... Read more

Publication date: Jul 03, 2020 mTOR signaling is an essential nutrient and energetic sensing pathway. Here we describe AIMTOR, a sensitive genetically encoded BRET (Bioluminescent Resonance Energy Transfer) biosensor to ... Read more

Publication date: Jul 03, 2020 Neurodevelopmental disorders have a heritable component and are associated with region specific alterations in brain anatomy. However, it is unclear how genetic risks for neurodevelopmental ... Read more