Publication date: Apr 20, 2021 Understanding synchrony in growing populations is important for applications as diverse as epidemiology and cancer treatment. Recent experiments employing fluorescent reporters in melanoma cell lines ... Read more

Publication date: Apr 20, 2021 Patients with metastatic melanoma and their physicians are confronted with a complex decision regarding first-line therapy. Risks and benefits vary considerably between various treatment options. ... Read more

Publication date: Apr 21, 2021 The aim of this study was to determine the risk factors for immune-related adverse events (irAEs) induced by immune checkpoint inhibitors. The authors conducted a ... Read more

Publication date: Apr 21, 2021 In patients with melanoma and asymptomatic brain metastases (MBM), nivolumab plus ipilimumab provided an intracranial response rate of 55%. Here, we present first report for ... Read more

Publication date: Apr 21, 2021 Patients’ phenotypic characteristics might be associated with melanoma aggressiveness, but the evidence is scarce. This study examined the associations between pigmentary characteristics, naevi and melanoma ... Read more

Publication date: Apr 21, 2021 Beyond the overall relapse-free survival (RFS) advantage demonstrated in randomized trials (RCT) of adjuvant anti-PD-1 immunotherapy in radically resected stage III-IV melanoma, key issues about ... Read more

Publication date: Apr 19, 2021 Recently studies found that APEX1 was abnormally expressed in melanoma, indicating that it might be involved in the development of melanoma. However, the underlying mechanism ... Read more

Publication date: Apr 19, 2021 Multiplex immunofluorescence (mIF) has arisen as an important tool for immuno-profiling tumor tissues. We updated our manual protocol into an automated protocol that allows the ... Read more

Publication date: Apr 20, 2021 Recent randomized data suggest that completion lymph node dissection after a positive sentinel lymph node biopsy (SLNB) improves locoregional control but does not improve survival ... Read more

Publication date: Apr 20, 2021 Malignant melanoma, an increasingly common form of skin cancer, poses a significant threat to public health, especially when the disease progresses past skin lesions to ... Read more