Publication date: Dec 05, 2019 Increasing numbers of patients are now offered immunotherapy as part of their cancer treatment. These treatments, while often very effective, have a wide range of ... Read more

Publication date: Dec 06, 2019 Uveal melanoma is the most common intraocular primary malignancy in adults and has been considered a fatal disease for decades. Optogenetics is an emerging technique ... Read more

Publication date: Dec 06, 2019 Traditional chemotherapy agents adversely affect wound healing and need to be held prior to or after surgery. Immune checkpoint inhibitors (ICIs) and targeted agents are ... Read more

Publication date: Dec 06, 2019 Circular RNAs (cicRNAs) have been identified to play pivotal roles in several cancer types. However, functions of circRNA in malignant melanoma are poor defined. Our ... Read more

Publication date: Dec 07, 2019 The regulation of mitochondrial biogenesis, melanogenesis, and connective tissue proteins is critical for homeostasis and aging skin cells. We examined the biological effects of polydeoxyribonucleotide ... Read more

Publication date: Dec 07, 2019 More than half of patients with melanoma use complementary and alternative medicine (CAM)(1). The same trend has been observed for patients with psoriasis(2) and hidradenitis ... Read more

Publication date: Dec 04, 2019 With the introduction of novel immune therapeutics for the treatment of disseminated malignancies, we sought to evaluate whether deliberate sequencing of immunotherapy before/after conventional cytotoxic ... Read more

Publication date: Dec 05, 2019 The organisation of cancer follow-up is under scrutiny in many countries, and general practice is suggested to become more involved. A central focus is timely ... Read more

Publication date: Dec 05, 2019 The dysfunction of type I interferon (IFN) signaling is an important mechanism of immune escape and metastasis in tumors. Increased NOS1 expression has been detected ... Read more

Publication date: Dec 05, 2019 Predicting metastasis in melanoma patients is important for disease management and could help to identify those who might benefit from adjuvant treatment. The aim of ... Read more