Publication date: May 01, 2020 The combination of liquid biomarkers from a single blood tube can provide more comprehensive information on tumor development and progression in cancer patients compared to ... Read more

Publication date: Jun 08, 2020 Patients with melanoma brain metastases (MBM) have a dismal prognosis, but the unprecedented advances in systemic therapy alone or in combination with local therapy have ... Read more

Publication date: Aug 08, 2020 Melanoma cells addicted to mutated BRAF oncogene activity can be targeted by specific kinase inhibitors until they develop resistance to therapy. We observed that the ... Read more

Publication date: Aug 27, 2020 Remarkable deregulation of several microRNAs (miRNAs) is demonstrated in cutaneous melanoma. hsa-miR-193a-3p is reported to be under-expressed in tissues and in plasma of melanoma patients, ... Read more

Publication date: Aug 31, 2020 The evolution of melanoma, the most aggressive type of skin cancer, is triggered by driver mutations that are acquired in the coding regions of particularly ... Read more

Publication date: Sep 23, 2020 To investigate conditional survival in patients with uveal melanoma in the United States DESIGN: Cohort study SUBJECTS: Patients were identified using International Classification of Disease ... Read more

Publication date: Dec 01, 2020 A series of imidazothiazole derivatives possessing potential activity against melanoma cells were investigated for molecular mechanism of action. The target compounds were tested against V600E-B-RAF ... Read more

Publication date: Oct 13, 2020 Mutational activation of the BRAF proto-oncogene in melanocytes reliably produces benign nevi (pigmented ‘moles’), yet the same change is the most common driver mutation in ... Read more

Publication date: Oct 13, 2020 Neurocutaneous melanosis (NCM; MIM # 249400; ORPHA: 2481], first reported by the Bohemian pathologist Rokitansky in 1861, and now more precisely defined as neurocutaneous melanocytosis, ... Read more

Publication date: Oct 13, 2020 Copper-64 is a useful theranostic radioisotope that is attracting renewed interest from the nuclear medicine community in the recent times. This study aims to demonstrate ... Read more