Publication date: Apr 21, 2025 Cutaneous malignant melanoma (CMM) is the most lethal form of skin cancer worldwide. The precise prediction of lymph node metastasis is critical for personalized treatment ... Read more

Publication date: Apr 19, 2025 Epilobium angustifolium L. is a perennial herbaceous plant known for various therapeutic properties, however its biological activity is not fully explored. In this study, we ... Read more

Publication date: Apr 21, 2025 A multimodal method comprising optical imaging using OCT and molecular detection using Raman spectroscopy was developed to explore its capability for noninvasive differentiation between melanoma ... Read more

Publication date: Apr 21, 2025 The von Hippel-Lindau (VHL) tumor suppressor gene product, pVHL, is frequently deficient in a variety of human cancers. In addressing the treatment of pVHL-deficient tumors, ... Read more

Publication date: Apr 21, 2025 In recent years, various gene therapy strategies have been developed for cancer treatment. One of these strategies is electroporation-based delivery of therapeutic transgenes – gene ... Read more

Publication date: Apr 21, 2025 Melanoma is a highly aggressive skin cancer with poor prognosis, highlighting the need for early detection. This study aims to develop a Tc-labeled single photon ... Read more

Publication date: Apr 21, 2025 Blockade of immune checkpoints, such as programmed death-ligand 1 (PD-L1), has shown promise in cancer treatment; however, clinical response remains limited in many cancer types. ... Read more

Publication date: Apr 18, 2025 Giant congenital melanocytic nevi (GCMN) are rare, large pigmented lesions present at birth that can significantly impact a patient’s physical appearance and psychological well-being. This ... Read more

Publication date: Apr 19, 2025 Abnormal innate immune response is a prominent feature underlying autoimmune diseases. One emerging factor driving dysregulated immune activation is cytosolic mitochondrial double-stranded RNAs (mt-dsRNAs). However, ... Read more

Publication date: Apr 19, 2025 Certain publications suggest that immunotherapy would be more effective if it were synchronised with the circadian oscillations of the immune system. We hypothesised that late ... Read more