Publication date: Oct 25, 2019 The purpose of this study is to test the effects of anti-PI-1 inhibitor (TSR-042) or anti-PD-1/anti-TIM-3 combination (TSR-042 / TSR-022) in patients with operable melanoma. ... Read more

Publication date: Oct 26, 2019 Urethral involvement has been singled out for the first time as a key factor in the risk for recurrence in women with vulvar malignant melanoma, ... Read more

Publication date: Oct 26, 2019 Now director of the Melanoma Medical Oncology Program at The Tisch Cancer Institute at Mount Sinai in New York City, the last two decades have ... Read more

Publication date: Oct 24, 2019 The primary objective is to assess the safety and tolerability of TAB004 in subjects with selected advanced solid malignancies, including lymphoma, and to evaluate the ... Read more

Publication date: Oct 22, 2019 The purpose of this study is to evaluate the safety, efficacy, pharmacokinetics, and V938 shedding in participants with advanced/metastatic or recurrent malignancies who receive V938 ... Read more

Publication date: Oct 21, 2019 DONIMI is a phase 1b trial testing the combination of domatinostat + nivolumab or nivolumab monotherapy in IFN-gamma signature high patients and of domatinostat + ... Read more

Publication date: Jul 26, 2019 Introduction: Few studies have examined melanoma incidence and survival rates among non-Hispanic black populations because melanoma risk is lower among this group than among non-Hispanic ... Read more

Publication date: Jul 24, 2019 This invention enables use of cytotoxic drugs that may be less likely to result in melanoma treatment resistance but would otherwise lack selectivity to . ... Read more

Publication date: Jul 22, 2019 Here, we found that skin fat cells (adipocytes) promoted metastatic initiation by sensitizing melanoma cells to TGF-β. Analysis of melanoma clinical samples revealed that adipocytes, ... Read more

Publication date: Jul 23, 2019 OBJECTIVE The aim of this study was to analyze the temporal evolution of melanoma incidence in the department of the Bas-Rhin, France, and to . ... Read more