Publication date: Aug 18, 2019 Postcraniotomy pain protocols use opioids, which are considered suboptimal analgesia following this procedure. Multimodal analgesia components are sparse. Our null hypothesis states that sumatriptan is ... Read more

Publication date: Aug 19, 2019 Canada is facing an urgent challenge to reduce the harms associated with opioids: from January 2016 to December of 2018, more than 11,500 individuals lost ... Read more

Publication date: Aug 19, 2019 Opioid tapering is increasingly utilized by providers to decrease risks of chronic opioid therapy, but it is unknown whether tapering is associated with termination of ... Read more

Publication date: Aug 20, 2019 The effectiveness of linking people from short-term in-patient managed withdrawal programs (‘detoxification’) to long-term, primary care-based buprenorphine is unknown. We tested whether buprenorphine initiation during ... Read more

Publication date: Aug 15, 2019 Opioid use is a significant national crisis impacting individuals struggling with addiction and their families. The majority of individuals who abuse opioids are of child-rearing ... Read more

Publication date: Aug 16, 2019 Richards, G.C. Treating postoperative pain? Avoid tramadol, long-acting opioid analgesics and long-term use. 03909. 2019 BMJ Evid Based Med. Concepts Keywords Analgesics Tramadol BMJ Opioids ... Read more

Publication date: Aug 16, 2019 The continued rise in fatalities from opioid analgesics despite a steady decline in the number of individual prescriptions directing ≥ 90 morphine milligram equivalents (MME)/day may ... Read more

Publication date: Aug 16, 2019 Postoperative overprescribing is common, and many patients will have excess medications. An effective method to encourage disposal is lacking. We hypothesized that a convenient home ... Read more

Publication date: Aug 17, 2019 The current emphasis on combatting the opioid epidemic in the United States and across the globe is well warranted, but rates and variations of other ... Read more

Publication date: Aug 15, 2019 Opioids target the μ-opioid receptor (MOR) to produce unrivaled pain management but their addictive properties can lead to severe abuse. We developed a whole animal ... Read more