Publication date: Apr 12, 2019 To discover through the patients themselves the process of coexisting with Parkinson’s disease. Qualitative study of phenomenological approach. The sample consisted of 6 participants. The ... Read more

Publication date: Apr 13, 2019 Impulsivity is an enduring personality trait that is highly relevant for the development of neuropsychiatric disorders. Although impulse control disorders (ICD) are well-characterized non-motor features ... Read more

Publication date: Apr 12, 2019 While the pathogenesis of Parkinson’s disease is not fully understood, there is increasing evidence that inflammatory responses in the brain are implicated in both disease ... Read more

Publication date: Apr 15, 2019 Parkinson’s disease (PD) is pathologically characterized by the progressive loss of dopaminergic (DA) neurons in the substantia nigra pars compacta (SNpc) and alpha-synucleinopathy. We mimic ... Read more

Publication date: Apr 15, 2019 Parkinson’s disease is characterized by a proteinopathy that includes aggregates of α-synuclein. A recent hypothesis proposes a prion-like spreading mechanism for this α-synucleinopathy. Early neuropathological ... Read more

Publication date: Apr 15, 2019 Parkinson’s disease (PD) is the second most common neurodegenerative disorder. We have previously developed a disease-in-a-dish model for familial PD using induced pluripotent stem cells ... Read more

Publication date: Apr 15, 2019 There is a need for methods that distinguish Parkinson’s disease (PD) from progressive supranuclear palsy (PSP) and multiple system atrophy (MSA), which have similar characteristics ... Read more

Publication date: Apr 16, 2019 MicroRNA-mediated (dys)regulation of gene expression has been implicated in Parkinson’s disease (PD), although results of microRNA expression studies remain inconclusive. We aimed to identify microRNAs ... Read more

Publication date: Apr 10, 2019 The Timed Up & Go test (TUG) is functional test and is a part of routine clinical examinations. The instrumented Timed Up & Go test ... Read more

Publication date: Apr 12, 2019 Garcinol, the principal phytoconstituent of plants belonging to the genus, Garcinia, is known for its anti-oxidant as well as anti-inflammatory properties, which can be extended ... Read more