Publication date: Feb 11, 2019 The prolonged reaction times seen in Parkinson’s disease (PD) have been linked to a dopaminergic-dependent deficit in using prior information to prepare responses, but also ... Read more

Publication date: Feb 15, 2019 Anxiety and depression are two frequent comorbidities of Parkinson’s disease (PD). However, the underlying neural mechanism is still unclear and the studies on their neural ... Read more

Publication date: Feb 15, 2019 The primary purpose of this study was to examine the feasibility and informativeness of the Patient-Specific Functional Scale (PSFS) for identifying activities that persons with ... Read more

Publication date: Feb 15, 2019 The discovery of disease-modifying therapies for Parkinson’s Disease (PD) represents a critical need in neurodegenerative medicine. Genetic mutations in LRRK2 are risk factors for the ... Read more

Publication date: Feb 14, 2019 Histamine H receptors (HRs) are co-expressed with dopamine D receptors (DRs) by striato-nigral medium spiny GABAergic neurons, where they functionally antagonize DR-mediated responses. We examined ... Read more

Publication date: Feb 14, 2019 Parkinson’s disease is one of the most common neurodegenerative illnesses in older persons and the leucine-rich repeat kinase 2 (LRRK2) is an auspicious target for ... Read more

Publication date: Feb 14, 2019 The dementia spectrum encompasses a range of disorders with complex diagnosis, pathophysiology and limited treatment options. Positron emission tomography (PET) imaging provides insights into specific ... Read more

Publication date: Feb 13, 2019 LRRK2 mutations, the most common genetic cause of Parkinson’s disease (PD) display incomplete penetrance, indicating the importance of other genetic and environmental influences on disease ... Read more

Publication date: Feb 15, 2019 Reactive balance responses are critical for fall prevention. Perturbation-based balance training (PBBT) has shown a positive effect in reducing the risk of falls among older ... Read more

Publication date: Feb 13, 2019 Parkinson’s disease (PD) is a chronic disorder that presents a range of premotor signs, such as sleep disturbances and cognitive decline, which are key non-motor ... Read more