Publication date: Mar 20, 2025 Functional neurological disorder (FND) is a common cause of neurological symptoms including seizures and movement disorders. It can be debilitating, is associated with high health ... Read more

Publication date: Mar 25, 2025 Background/Objectives: Parkinson’s disease (PD) and hypertension are often coexistent conditions that interact in entwined ways at various levels. Cardiovascular autonomic dysfunction (CAD), a non-motor feature ... Read more

Publication date: Mar 27, 2025 A systematic review on the association of mitochondrial DNA copy number (mtDNA-CN) with Alzheimer’s disease (AD) and Parkinson disease (PD) is lacking and the causal ... Read more

Publication date: Apr 01, 2025 Mild Behavioral Impairment (MBI) is characterized by later-life emergent and persistent neuropsychiatric symptoms (NPS) in older adults without dementia, serving as a potential precursor to ... Read more

Publication date: Apr 02, 2025 Background: Understanding how sociodemographic factors influence knowledge, attitudes, and practices (KAP) related to Parkinson’s disease (PD) is essential for developing targeted interventions. This study examines ... Read more

Publication date: Apr 02, 2025 In synucleinopathies, including Parkinson’s disease (PD), dopamine neurons in the substantia nigra pars compacta (SNc) exhibit greater vulnerability to degeneration than those in the ventral ... Read more

Publication date: Apr 03, 2025 α-Synuclein (αSyn) can misfold and aggregate to form fibrillar cDF-sheet-rich aggregates (“strains”) that are phosphorylated (p-αSyn) and deposited into intracellular inclusions in the brain, the ... Read more

Publication date: Apr 03, 2025 The progressive loss of dopaminergic neurons and abnormal iron deposition in the central nervous system (CNS) are key pathogenic mechanisms of Parkinson’s disease (PD). This ... Read more

Publication date: Apr 08, 2025 Deep stimulation of the subthalamic nucleus (DBS STN) is a highly effective and relatively safety method of surgical treatment of Parkinson’s disease (PD), which can ... Read more

Publication date: Apr 17, 2025 Parkinson’s disease (PD) is a complex neurodegenerative disorder with both motor and non-motor symptoms (NMS), the latter having a profound impact on patients’ quality of ... Read more