Publication date: Jan 28, 2023 The sympathetic skin response (SSR) is a well-established test, whereas the electrochemical skin conductance (ESC) is still under evaluation. Our aim was therefore to assess ... Read more

Publication date: Jan 30, 2023 Mutations in LRRK2 are the most common genetic cause of Parkinson’s disease. Despite substantial research efforts, the physiological and pathological role of this multidomain protein ... Read more

Publication date: Jan 30, 2023 Development of neuroprotective therapeutics for Parkinson’s disease (PD) is facing a lack of translation from pre-clinical to clinical trials. One strategy for improvement is to ... Read more

Publication date: Jan 30, 2023 N-methyl-d-aspartate receptor (NMDAR) encephalitis is an autoantibody-mediated neurological syndrome with prominent cognitive and neuropsychiatric symptoms. The clinical relevance of NMDAR antibodies outside the context of ... Read more

Publication date: Jan 30, 2023 Oral levodopa is the most effective treatment for Parkinson disease, but OFF periods emerge over time. Gastrointestinal dysfunction and food effects impact levodopa absorption, contributing ... Read more

Publication date: Jan 30, 2023 Parkinson’s disease (PD) is a neuro-motor ailment that strikes adults in their older life and results in both motor and non-motor impairments. In neuronal and ... Read more

Publication date: Jan 30, 2023 Deletion and missense or nonsense mutation of RAB39B gene cause familial Parkinson’s disease (PD). We hypothesized that deletion and mutation of RAB39B gene induce degeneration ... Read more

Publication date: Jan 30, 2023 Sleep disorders are among the most common non-motor symptoms in Parkinson’s disease (PD) and are associated with reduced cognition and health-related quality of life. Disturbed ... Read more

Publication date: Feb 17, 2023 Aberrant proteostasis is thought to be implicated in Parkinson’s disease (PD), but patient-derived evidence is scant. We hypothesized that impaired proteostasis is reflected as altered ... Read more

Publication date: Jan 29, 2023 N6-methyladenosine modification of RNA (m A) regulates translational control which may influence neuronal dysfunction underlying neurodegenerative diseases. Using microscopy and a machine learning approach, we ... Read more