Publication date: Jun 22, 2022 The prevailing network perspective of Parkinson’s disease (PD) emerges not least from the ascending neuropathology traceable in histological studies. However, whether longitudinal in vivo correlates ... Read more

Publication date: Jun 22, 2022 Brain-Derived Neurotrophic Factor (BDNF) is an essential mediator of brain assembly, development, and maturation. BDNF has been implicated in a variety of brain disorders such ... Read more

Publication date: Jun 22, 2022 Intranasal delivery has great potential to cross the blood-brain barrier and deliver the drug molecule into the central nervous system faster than traditional methods. The ... Read more

Publication date: Jun 23, 2022 Parkinson’s disease (PD) is a neurodegenerative disorder caused by disruption of dopamine-producing cells. PD is associated with motor symptoms and nonmotor symptoms including depression and ... Read more

Publication date: Jun 23, 2022 Proenkephalin (PENK) and prodynorphin (PDYN) are peptides mainly produced by the striatal medium spiny projection neurons (MSNs) under dopaminergic signaling. Therefore, they may represent candidate ... Read more

Publication date: Jun 23, 2022 Together with neuronal loss, the existence of insoluble inclusions of alpha-synuclein (α-syn) in the brain is widely accepted as a hallmark of synucleinopathies including Parkinson’s ... Read more

Publication date: Jun 23, 2022 TeleDREAMS, a distance learning version of the Developing a Research Participation Enhancement and Advocacy Training Program for Diverse Seniors (DREAMS) program, provides remote clinical research ... Read more

Publication date: Jul 01, 2022 Freezing of gait (FoG) is a serious symptom of Parkinson’s disease and prompt detection of FoG is crucial for fall prevention. Although multimodal data combining ... Read more

Publication date: Jun 22, 2022 The G2385R variant of leucine-rich repeat kinase 2 (LRRK2) is mainly associated with Parkinson’s disease(PD) in Asian populations. The aim of this study was to ... Read more

Publication date: Aug 01, 2022 Parkinson’s disease (PD) is characterized by the selective death of substantia nigra pars compacta (SNpc) dopaminergic neurons and includes both motor and non-motor symptoms. While ... Read more