Publication date: Jan 22, 2020 Multiple sclerosis (MS) affects approximately 1 million persons in the United States, and is the leading cause of neurological disability in young adults. The concept ... Read more

Publication date: Jan 21, 2020 De novo mutations (DNMs), or mutations that appear in an individual despite not being seen in their parents, are an important source of genetic variation ... Read more

Publication date: Jan 22, 2020 Magnetic resonance imaging (MRI) has revolutionized the diagnosis and management of people living with multiple sclerosis (MS). However, conventional MRI sequences and measures currently used ... Read more

Publication date: Jan 22, 2020 Multiple sclerosis (MS) is a chronic, inflammatory disease of the central nervous system (CNS), affecting patients of all ages, causing neurologic disability if inadequately treated. ... Read more

Publication date: Jan 18, 2020 Precision medicine (PM) means the customization of healthcare with decisions and practices adjusted to the individual patient. It includes personalized diagnostics, patients’ sub-classification, individual treatment ... Read more

Publication date: Jan 20, 2020 High-throughput genome sequencing and computation have enabled rapid identification of targets for personalized medicine, including cancer vaccines. Synthetic peptides are an established mode of cancer ... Read more

Publication date: Jan 20, 2020 Introduction: Pharmacometabolomics is an emerging science pursuing the application of precision medicine. Combining both genetic and environmental factors, the so-called pharmacometabolomic approach guides patient selection ... Read more

Publication date: Jan 20, 2020 The promise of precision medicine will only be realized if the healthcare system adapts to meet some key infrastructure needs. Among these needs are adequate ... Read more

Publication date: Jan 18, 2020 Cancer immunotherapies are promising treatments for many forms of cancer. Nevertheless, the response rates to, e.g., immune checkpoint inhibitors (ICI), are still in low double-digit ... Read more

Publication date: Jan 15, 2020 The complexity of cancer diseases demands bioinformatic techniques and translational research based on big data and personalized medicine. Open data enables researchers to accelerate cancer ... Read more