Publication date: May 01, 2021 Intrahepatic cholangiocarcinoma (ICC) remains one of the most intractable malignancies. The development of effective drug treatments for ICC is seriously hampered by the lack of ... Read more

Publication date: May 01, 2021 Intrahepatic cholangiocarcinoma (ICC) remains one of the most intractable malignancies. The development of effective drug treatments for ICC is seriously hampered by the lack of ... Read more

Publication date: Aug 12, 2021 To develop a crude screening method for detecting biomarkers which frequently exhibit a rise (or fall) in level prior to a serious event (e. g. ... Read more

Publication date: Aug 10, 2021 Breast cancer Patient Derived Organoids (PDO) have been demonstrated to be a reliable model to study cancer that promised to replace and reduce the use ... Read more

Publication date: Aug 10, 2021 Induced pluripotent stem cells (iPSCs) are produced from adult somatic cells through reprogramming, which behave like embryonic stem cells (ESCs) but avoiding the controversial ethical ... Read more

Publication date: Aug 11, 2021 To fully appreciate genetics, one must understand the link between genotype (DNA sequence) and phenotype (observable characteristics). Advances in high-throughput genomic sequencing technologies and applications, ... Read more

Publication date: Aug 11, 2021 Randomized trials recruit diverse patients, including some individuals who may be unresponsive to the treatment. Here we follow up on prior conceptual advances and introduce ... Read more

Publication date: Aug 09, 2021 Single-cell technologies are emerging as powerful tools for cancer research. These technologies characterize the molecular state of each cell within a tumor, enabling new exploration ... Read more

Publication date: Aug 09, 2021 CRISPR-based cancer dependency maps are accelerating advances in cancer precision medicine, but adequate functional maps are limited to the most common oncogenes. To identify opportunities ... Read more

Publication date: Aug 09, 2021 The field of pharmacogenomics focuses on the way a person’s genome affects his or her response to a certain dose of a specified medication. The ... Read more