Publication date: May 01, 2019 Precision health relies on the ability to assess disease risk at an individual level, detect early preclinical conditions and initiate preventive strategies. Recent technological advances ... Read more

Publication date: Aug 16, 2019 The establishment of precision medicine in cancer patients requires the study of several biomarkers. Single-gene testing approaches are limited by sample availability and turnaround time. ... Read more

Publication date: Aug 16, 2019 Identifying recurrent somatic genetic alterations of, and dependency on, the kinase BRAF has enabled a “precision medicine” paradigm to diagnose and treat BRAF-driven tumors. Although ... Read more

Publication date: Aug 19, 2019 Rocca, A., Melegari, E., and Palleschi, M. Precision medicine: PI3K targeting in advanced breast cancer. 05224. 2019 Breast Cancer Res Treat. Concepts Keywords Breast Cancer ... Read more

Publication date: Aug 19, 2019 The central concept underlying precision medicine is a mechanistic understanding of each disease and its response to therapy sufficient to direct a specific intervention. To ... Read more

Publication date: Aug 19, 2019 Digital health is poised to transform health care and redefine personalized health. As Internet and mobile phone usage increases, as technology develops new ways to ... Read more

Publication date: Aug 20, 2019 Circadian timing of treatments can largely improve tolerability and efficacy in patients. Thus, drug metabolism and cell cycle are controlled by molecular clocks in each ... Read more

Publication date: Aug 14, 2019 One of the best-established area within multi-omics is proteogenomics, whereby the underpinning technologies are next-generation sequencing (NGS) and mass spectrometry (MS). Proteogenomics has contributed significantly ... Read more

Publication date: Aug 14, 2019 Frailty encompasses several domains (i.e., metabolic, physical, cognitive). The multisystem derangements underlying frailty pathophysiology, its phenotypic heterogeneity, and the fluctuations of individuals across severity states ... Read more

Publication date: Aug 16, 2019 In recent years, precision medicine has emerged as a charismatic name for a growing movement to revolutionise biomedicine by bringing genomic knowledge and sequencing to ... Read more