Publication date: Mar 21, 2025 The Pup-proteasome system (PPS) is a unique bacterial proteolytic pathway found in some bacterial species, including in Mycobacterium tuberculosis, that plays a vital role in ... Read more

Publication date: Mar 21, 2025 The treatment of mycobacteriosis depends on the species causing the disease and its susceptibility to drugs. Clarithromycin represents the cornerstone of regimens for fast-growing non-tuberculous ... Read more

Publication date: Mar 22, 2025 Xpert MTB/RIF Ultra (Ultra) aimed to improve the specificity in identifying rifampicin-resistant tuberculosis (RR-TB), compared to Xpert MTB/RIF. In a nationwide study in Rwanda, patients ... Read more

Publication date: Mar 22, 2025 Tuberculosis (TB), caused by Mycobacterium tuberculosis (Mtb), remains one of the leading causes of death worldwide. TB pathogenesis is shaped by a complex interaction between ... Read more

Publication date: Mar 24, 2025 Accurate and rapid diagnosis is crucial for ending the tuberculosis epidemic. Truenat assays are World Health Organization (WHO)-recommended rapid molecular diagnostic tests that detect Mycobacterium ... Read more

Publication date: Mar 21, 2025 Advanced HIV disease (AHD) is increasingly becoming a threat to the survival of people living with HIV. Many countries, including Malawi, have adopted and adapted ... Read more

Publication date: Mar 01, 2025 Few studies have assessed tuberculosis (TB) disease incidence and risk in a large US-based cohort with long-term longitudinal follow-up. In a retrospective cohort study from ... Read more

Publication date: Mar 19, 2025 Hepcidin is the primary regulator of vertebrate iron homeostasis. Its production is stimulated by systemic iron levels and inflammatory signals. Although the role of hepcidin ... Read more

Publication date: Mar 19, 2025 Tuberculosis poses a rare but life-threatening complication for patients undergoing hematopoietic stem cell transplantation. In a case series spanning January 2020 to January 2024, we ... Read more

Publication date: Mar 20, 2025 The increasing prevalence of antibiotic resistance, the stagnation of antibiotic development, and the adaptive capacity of bacteria to subvert the host immune response combine to ... Read more