Major Depressive Disorder (MDD), commonly referred to as clinical depression or major depression, is a mental health condition characterized by persistent feelings of sadness, hopelessness, and a loss of interest or pleasure in activities. It is a serious and debilitating condition that affects a person’s emotions, thoughts, and behaviors.

The exact cause of major depressive disorder is not fully understood, but it is believed to involve a complex interaction of genetic, biological, environmental, and psychological factors. Certain risk factors may increase the likelihood of developing depression, including a family history of the disorder, personal history of other mental health conditions, traumatic life events, chronic illness, substance abuse, and certain medications.

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