A targeted genomic alteration analysis predicts survival of melanoma patients under BRAF inhibitors.
Publication date: Mar 01, 2019 Several mechanisms have been described to elucidate the emergence of ...
Melanoma
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Inhibition of melanin synthesis and melanosome transfer by chitosan biomaterials.
Publication date: Aug 22, 2019 Decreasing skin pigmentation is desirable for various medical or cosmetic ... -
Dnmt3a is required for the tumor stemness of B16 melanoma cells.
Publication date: Aug 22, 2019 The relationship of carcinogenesis and DNA methyltransferases has attracted extensive ... -
Imaging challenges of immunotherapy and targeted therapy in patients with brain metastases: Response, Progression, and Pseudoprogression.
Publication date: Aug 22, 2019 The advent of immunotherapy using immune checkpoint inhibitors (ICI) and ... -
Genetic variants in glutamine metabolic pathway genes predict cutaneous melanoma-specific survival.
Publication date: Aug 22, 2019 Glutamine dependence is a unique metabolic defect seen in cutaneous ... -
Granulomatous/sarcoid-like reactions in the setting of PD-1 inhibition: a potential mimic of disease recurrence.
Publication date: Aug 22, 2019 Nivolumab and pembrolizumab are humanized IgG4 monoclonal antibodies against programmed ... -
Role of 18F-Fluorodeoxyglucose Positron Emission Tomography or Positron Emission Tomography/Computed Tomography for the Detection of Recurrent Disease after Treatment of Malignant Melanoma.
Publication date: Aug 22, 2019 The purpose of the current study was to investigate the ... -
A pediatric case of pigmented epithelioid melanocytoma with chromosomal copy number alterations in 15q and 17q and a novel NTRK3-SCAPER gene fusion.
Publication date: Aug 22, 2019 Pigmented epithelioid melanocytoma (PEM) represents a group of rare, heavily ... -
Metabolic landscape of the tumor microenvironment at single cell resolution.
Publication date: Aug 21, 2019 The tumor milieu consists of numerous cell types each existing ... -
The inhibitory effect of silk sericin against ultraviolet-induced melanogenesis and its potential use in cosmeceutics as an anti-hyperpigmentation compound.
Publication date: Aug 21, 2019 Ultraviolet radiation (UVR)-induced redox imbalance in melanocytes triggers the activation ... -
The dysfunction of BP180/collagen XVII in keratinocytes promotes melanoma progression.
Publication date: Aug 21, 2019 BP180, also termed collagen XVII, is a hemidesmosomal transmembrane glycoprotein ... -
Exhaustion of CD4+ T-cells mediated by the Kynurenine Pathway in Melanoma.
Publication date: Aug 21, 2019 Kynurenine pathway (KP) activation by the enzymatic activity of indoleamine ... -
A retrospective chart review study describing metastatic melanoma patients profile and treatment patterns in Spain.
Publication date: Aug 21, 2019 To describe patient characteristics by disease stage, resectability status and ... -
Quinalizarin induces cycle arrest and apoptosis via reactive oxygen species-mediated signaling pathways in human melanoma A375 cells.
Publication date: Aug 20, 2019 Quinalizarin, a bioactive and highly selective compound, is known to ... -
Binimetinib in heavily pretreated NRAS-mutant Melanoma Patients with Brain Metastases.
Publication date: Aug 22, 2019 Brain metastases are frequent in metastatic melanoma patients and indicate ... -
Mitofusins modulate the increase in mitochondrial length, bioenergetics and secretory phenotype in therapy-induced senescent melanoma cells.
Publication date: Aug 20, 2019 Cellular senescence is an endpoint of chemotherapy, and targeted therapies ... -
DROSHA-Dependent AIM2 Inflammasome Activation Contributes to Lung Inflammation during Idiopathic Pulmonary Fibrosis.
Publication date: Aug 20, 2019 Idiopathic pulmonary fibrosis (IPF) has been linked to chronic lung ... -
Mcl-1 Inhibitor Induces Cells Death in BRAF-Mutant Amelanotic Melanoma Trough GSH Depletion, DNA Damage and Cell Cycle Changes.
Publication date: Aug 20, 2019 Mcl-1 is a potent antiapoptotic protein and amplifies frequently in ... -
Identification of recurrent activating HER2 mutations in primary canine pulmonary adenocarcinoma.
Publication date: Aug 20, 2019 Naturally occurring primary canine lung cancers share clinicopathologic features with ... -
Dermoscopy for melanoma detection and triage in primary care: a systematic review.
Publication date: Aug 20, 2019 Most skin lesions first present in primary care, where distinguishing ... -
Adverse events associated with encorafenib plus binimetinib in the COLUMBUS study: incidence, course and management.
Publication date: Aug 19, 2019 Dual inhibition of the mitogen-activated protein kinase pathway with BRAF/MEK ...