Melanoma
This magazine is directed toward patients with Melanoma, their families, care givers, physicians and researchers. The content is gathered, validated, categorized, and supplied using a novel big data cyberinfrastructure technology that continually learns about Melanoma.
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Overall survival after treatment for metastatic uveal melanoma: a systematic review and meta-analysis.
Publication date: Jan 16, 2019 The overall survival (OS) of patients with metastatic uveal melanoma ... -
Remote partner assisted skin self-examination skills training of melanoma survivors and their partners.
Publication date: Feb 01, 2019 Robinson, J.K., Reavy, R., Mallett, K.A., and Turrisi, R. Remote ... -
Dynamic evolution of clonal composition and neoantigen landscape in recurrent metastatic melanoma with a rare combination of driver mutations.
Publication date: Feb 15, 2019 In melanoma, initiating oncogenic mutations in BRAF or NRAS are ... -
Treatment in metastatic melanoma – Time to re-think.
Publication date: Feb 15, 2019 Schadendorf, D., Livingstone, E., and Zimmer, L. Treatment in metastatic ... -
A Study of XmAb®22841 Monotherapy & in Combination w/ Pembrolizumab in Subjects w/ Selected Advanced Solid Tumors
Publication date: Feb 21, 2019 This is a Phase 1, multiple dose, ascending-dose escalation study ... -
Absence of Intraocular Lymphatic Vessels in Uveal Melanomas with Extrascleral Growth.
Publication date: Feb 15, 2019 The aim of this study was to investigate the presence ... -
Markedly Reduced Risk of Internal Malignancies in Patients With Vitiligo: A Nationwide Population-Based Cohort Study.
Publication date: Feb 20, 2019 Recent studies indicated that the autoimmunity of vitiligo exerts effects ... -
Clonal Deletion of Tumor-Specific T Cells by Interferon-γ Confers Therapeutic Resistance to Combination Immune Checkpoint Blockade.
Publication date: Feb 19, 2019 Resistance to checkpoint-blockade treatments is a challenge in the clinic. ... -
Natural T cell autoreactivity to melanoma antigens: clonally expanded melanoma-antigen specific CD8 + memory T cells can be detected in healthy humans.
Publication date: Feb 19, 2019 We used four-color ImmunoSpot(R) assays, in conjunction with peptide pools ... -
Loss of BOP1 confers resistance to BRAF kinase inhibitors in melanoma by activating MAP kinase pathway.
Publication date: Feb 19, 2019 Acquired resistance to BRAF kinase inhibitors (BRAFi) is the primary ... -
Evaluation of apoptosis imaging biomarkers in a genetic model of cell death.
Publication date: Feb 19, 2019 We have previously developed the caspase-based radiotracer, F-ICMT-11, for PET ... -
Late-onset isolated adrenocorticotropic hormone deficiency caused by nivolumab: a case report.
Publication date: Feb 19, 2019 Immune checkpoint inhibitors including nivolumab, an anti-programmed cell death protein ... -
Mitotic rate as an important prognostic factor in cutaneous malignant melanoma.
Publication date: Feb 19, 2019 Recently, the quantification of mitoses in cutaneous melanoma has been ... -
Analysis of mucosal melanoma whole-genome landscapes reveals clinically relevant genomic aberrations.
Publication date: Feb 19, 2019 Unlike advances in the genomics-driven precision treatment of cutaneous melanomas, ... -
The X-linked inhibitor of apoptosis protein (XIAP) is involved in melanoma invasion by regulating cell migration and survival.
Publication date: Feb 18, 2019 The X-linked inhibitor of apoptosis (XIAP) is a potent cellular ... -
MicroRNA-363-3p/p21(Cip1/Waf1) axis is regulated by HIF-2α in mediating stemness of melanoma cells.
Publication date: Feb 20, 2019 Melanoma is a malignant tumor. The acquisition of stemness of ... -
Leukocyte⁻Cancer Cell Fusion-Genesis of a Deadly Journey.
Publication date: Feb 18, 2019 According to estimates from the International Agency for Research on ... -
Prevalence and cellular distribution of novel immune checkpoint targets across longitudinal specimens in treatment-naïve melanoma: implications for clinical trials.
Publication date: Feb 18, 2019 Immunotherapies targeting co-stimulating and co-inhibitory checkpoint receptors beyond PD-1 and ... -
Statistical assessment and visualization of synergies for large-scale sparse drug combination datasets.
Publication date: Feb 18, 2019 Drug combinations have the potential to improve efficacy while limiting ... -
Recurrent Pneumonitis in Patients with Melanoma Treated with Immune Checkpoint Inhibitors.
Publication date: Feb 18, 2019 Immune checkpoint inhibitors (ICIs) have changed the oncologic landscape in ...