Recognising Skin Cancer in Primary Care.
Publication date: Nov 16, 2019 Skin cancer, including melanoma, basal cell carcinoma and cutaneous squamous ...
Melanoma
This magazine is directed toward patients with Melanoma, their families, care givers, physicians and researchers. The content is gathered, validated, categorized, and supplied using a novel big data cyberinfrastructure technology that continually learns about Melanoma.
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Loss of BAP1 in Pheochromocytomas and Paragangliomas Seems Unrelated to Genetic Mutations.
Publication date: Nov 16, 2019 Breast cancer-associated protein 1 (BAP1) gene is a broad-spectrum tumor ... -
Cross-Talk Between circRNAs and mRNAs Modulates MiRNA-mediated Circuits and Affects Melanoma Plasticity.
Publication date: Nov 16, 2019 CircularRNAs (circRNAs) are non-coding RNAs which compete for microRNA (miRNA) ... -
Potent Cytotoxicity of Novel L-Shaped Ortho-Quinone Analogs through Inducing Apoptosis.
Publication date: Nov 15, 2019 Twenty-seven L-shaped ortho-quinone analogs were designed and synthesized using a ... -
Interleukin-18 Is a Prognostic Biomarker Correlated with CD8 T Cell and Natural Killer Cell Infiltration in Skin Cutaneous Melanoma.
Publication date: Nov 15, 2019 Interleukin-18 (IL-18) is a cytokine that enhances innate and adaptive ... -
Efficacy of Cancer Immunotherapy: An Umbrella Review of Meta-analyses of Randomized Controlled Trials.
Publication date: Nov 15, 2019 We conducted a systematic review for evidence of the clinical ... -
A T-helper 1/interferon- gene signature is prognostic in the adjuvant setting of resectable high-risk melanoma but not in non-small cell lung cancer.
Publication date: Nov 15, 2019 Immune components of the tumor microenvironment (TME) have been associated ... -
Extended 5-Year Follow-up Results of a Phase Ib Study (BRIM7) of Vemurafenib and Cobimetinib in BRAF-Mutant Melanoma.
Publication date: Nov 15, 2019 To report the 5-year overall survival (OS) landmark and the ... -
Iris biopsy to investigate feline iris hyperpigmentation.
Publication date: Nov 16, 2019 To evaluate the benefit of iris biopsy in cats with ... -
Multiple antibodies targeting tumor-specific mutations redirect immune cells to inhibit tumor growth and increase survival in experimental animal models.
Publication date: Nov 16, 2019 T cell therapy for cancer involves genetic introduction of a ... -
Multiple interaction nodes define the post-replication repair response to UV-induced DNA damage that is defective in melanomas and correlated with UV signature mutation load.
Publication date: Nov 16, 2019 Ultraviolet radiation-induced DNA mutations are a primary environmental driver of ... -
Comparison of dermoscopic features between congenital and acquired acral melanocytic nevi in Korean patients.
Publication date: Nov 16, 2019 The dermoscopic patterns of acral melanocytic nevi (AMNs) are crucial ... -
Circulating tumour DNA (ctDNA) as a biomarker in metachronous melanoma and colorectal cancer- a case report.
Publication date: Nov 14, 2019 Circulating tumour DNA (ctDNA) has emerged as a promising blood-based ... -
Dual checkpoint inhibitor-associated eosinophilic enteritis.
Publication date: Nov 15, 2019 Eosinophilia has been reported as a rare, new biological effect ... -
Contribution of Common Genetic Variants to Familial Aggregation of Disease and Implications for Sequencing Studies.
Publication date: Nov 15, 2019 Despite genetics being accepted as the primary cause of familial ... -
Discovery of a First-in-class Mitogen-Activated Protein Kinase Kinase 1/2 (MEK1/2) Degrader.
Publication date: Nov 15, 2019 MEK1 and MEK2 (also known as MAP2K1 and MAP2K2) are ... -
The density and spatial tissue distribution of CD8 and CD163 immune cells predict response and outcome in melanoma patients receiving MAPK inhibitors.
Publication date: Nov 15, 2019 Clinical response to MAPK inhibitors in metastatic melanoma patients is ... -
Early fatigue in cancer patients receiving PD-1/PD-L1 checkpoint inhibitors: an insight from clinical practice.
Publication date: Nov 15, 2019 Fatigue was reported as the most common any-grade adverse event ... -
Mechanisms regulating PD-L1 expression on tumor and immune cells.
Publication date: Nov 15, 2019 The PD-1/PD-L1 checkpoint is a central mediator of immunosuppression in ... -
A cross-sectional analysis of skin cancer risk in patients receiving narrow-band ultraviolet B phototherapy: an evaluation of 100 patients.
Publication date: Nov 15, 2019 Narrow-band ultraviolet B (NB-UVB) phototherapy is an effective and widely ... -
Supramolecular Insights into Domino Effects of Ag@ZnO-induced Oxidative Stress in Melanoma Cancer Cells.
Publication date: Nov 15, 2019 Recent studies suggest that cancer cell death accompanied by organelle ...