Spliceosomal disruption of the non-canonical BAF complex in cancer.
Publication date: Oct 09, 2019 SF3B1 is the most commonly mutated RNA splicing factor in ...
Melanoma
This magazine is directed toward patients with Melanoma, their families, care givers, physicians and researchers. The content is gathered, validated, categorized, and supplied using a novel big data cyberinfrastructure technology that continually learns about Melanoma.
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Relating the gut metagenome and metatranscriptome to immunotherapy responses in melanoma patients.
Publication date: Oct 09, 2019 Recent evidence suggests that immunotherapy efficacy in melanoma is modulated ... -
Extracellular Vesicles Shedding Promotes Melanoma Growth in Response to Chemotherapy.
Publication date: Oct 09, 2019 Extracellular vesicles (EVs) are emerging as key players in intercellular ... -
TRIM59 loss in M2 macrophages promotes melanoma migration and invasion by upregulating MMP-9 and Madcam1.
Publication date: Oct 10, 2019 The culture supernatant from macrophages overexpressing TRIM59 has a cytotoxic ... -
Novel functional proteins coded by the human genome discovered in metastases of melanoma patients.
Publication date: Oct 10, 2019 In the advanced stages, malignant melanoma (MM) has a very ... -
Investigating the role of immunotherapy in advanced/recurrent female genital tract melanoma: a preliminary experience.
Publication date: Nov 01, 2019 immunotherapy with immune checkpoint inhibitors has become one of the ... -
Primary Spinal Cord Melanoma of Intradural Extramedullary Origin.
Publication date: Jul 01, 2019 Primary malignant melanoma is the very rare entity of the ... -
Implementation of the SunSmart program and population sun protection behaviour in Melbourne, Australia: Results from cross-sectional summer surveys from 1987 to 2017.
Publication date: Oct 01, 2019 Australia has one of the highest skin cancer rates in ... -
Maintaining Quality of Life: Electrochemotherapy for Palliative Periorbital Malignancy.
Publication date: Oct 04, 2019 Electrochemotherapy has been used successfully for treatment of recurrent head ... -
Targeted co-delivery of Trp-2 polypeptide and monophosphoryl lipid A by pH-sensitive poly (β-amino ester) nano-vaccines for melanoma.
Publication date: Oct 05, 2019 Dendritic cell (DC)-targeted vaccines based on nanotechnology are a promising ... -
Leveraging transcriptional dynamics to improve BRAF inhibitor responses in melanoma.
Publication date: Oct 05, 2019 Melanoma is a heterogeneous tumour, but the impact of this ... -
Predicting response to pembrolizumab in metastatic melanoma by a new personalization algorithm.
Publication date: Oct 07, 2019 At present, immune checkpoint inhibitors, such as pembrolizumab, are widely ... -
High GILT Expression and an Active and Intact MHC Class II Antigen Presentation Pathway Are Associated with Improved Survival in Melanoma.
Publication date: Oct 07, 2019 The MHC class I Ag presentation pathway in melanoma cells ... -
Gastrointestinal tract dysbiosis enhances distal tumor progression through suppression of leukocyte trafficking.
Publication date: Oct 07, 2019 The overall use of antibiotics has increased significantly in recent ... -
ADP secreted by dying melanoma cells mediates chemotaxis and chemokine secretion of macrophages via the purinergic receptor P2Y12.
Publication date: Oct 07, 2019 Melanoma immunotherapy is still not satisfactory due to immunosuppressive cell ... -
Loss of CYLD accelerates melanoma development and progression in the Tg(Grm1) melanoma mouse model.
Publication date: Oct 07, 2019 The deubiquitinase cylindromatosis (CYLD) is a well-known tumor suppressor, found ... -
ABCB5 is activated by MITF andβ-catenin and is associated with melanoma differentiation.
Publication date: Oct 08, 2019 Defining markers of different phenotypic states in melanoma is important ... -
A Metabolically Stable Boron-Derived Tyrosine Serves as a Theranostic Agent for Positron Emission Tomography Guided Boron Neutron Capture Therapy.
Publication date: Oct 08, 2019 Boronophenylalanine (BPA) is the dominant boron delivery agent for boron ... -
Lopinavir Loaded Spray Dried Liposomes with Penetration Enhancers for Cytotoxic Activity.
Publication date: Oct 08, 2019 HIV protease inhibitors (HIV-PI) are the drugs utilized for the ... -
Hypoxic Gene Signature of Primary and Metastatic Melanoma Cell Lines: Focusing on HIF1-Beta and NDRG-1
Publication date: Oct 09, 2019 Hypoxia is an important microenvironmental factor significantly affecting tumor proliferation ... -
Clinical and prognostic value of 18F-FDG-PET/CT in the restaging process of recurrent cutaneous melanoma.
Publication date: Oct 09, 2019 The aim of this retrospective multicenter study was to evaluate ...