Mutant BRAF and MEK inhibitors regulate the tumor immune microenvironment via pyroptosis.
Publication date: Dec 03, 2019 Combinations of BRAF inhibitors and MEK inhibitors (BRAFi + MEKi) ...
Melanoma
This magazine is directed toward patients with Melanoma, their families, care givers, physicians and researchers. The content is gathered, validated, categorized, and supplied using a novel big data cyberinfrastructure technology that continually learns about Melanoma.
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Use of electrochemotherapy in women with vulvar cancer to improve quality-of-life in the palliative setting: a meta-analysis.
Publication date: Dec 03, 2019 Electrochemotherapy involves the use of transient tumor permeabilization via electric ... -
YAP/TAZ Activation Drives Uveal Melanoma Initiation and Progression.
Publication date: Dec 03, 2019 Uveal melanoma (UM), the most common ocular malignancy, is characterized ... -
The interplay of sun-damage and genetic risk in Australian multiple and single primary melanoma cases and controls.
Publication date: Dec 03, 2019 Skin phenotype, host genotype and UV damage play a role ... -
Robust immunoscore model to predict the response to anti-PD1 therapy in melanoma.
Publication date: Dec 03, 2019 This study aimed to construct immune-related predictors to identify responders ... -
Multiple nivolumab-induced CNS demyelination with spontaneous resolution in an asymptomatic metastatic melanoma patient.
Publication date: Dec 02, 2019 Immune checkpoint inhibitors (ICPis) have revolutionised the treatment of melanoma ... -
Hormone replacement therapy and the risk of melanoma in post-menopausal women.
Publication date: Dec 05, 2019 Is hormone replacement therapy (HRT) associated with an increased risk ... -
Human p21-activated kinase 5 (PAK5) expression and potential mechanisms in relevant cancers: Basic and clinical perspectives for molecular cancer therapeutics.
Publication date: Dec 02, 2019 An oncogenic role, p21-activated kinase 5 (PAK5), has proven as ... -
Transdermal metformin hydrochloride-loaded cubic phases: in silico formulation optimization, preparation, properties, and application for local treatment of melanoma.
Publication date: Dec 01, 2019 Metformin hydrochloride (Met) is commonly used for antidiabetic therapy though ... -
Tumour-to-tumour Metastasis: Cutaneous Melanoma Metastasizing to Leiomyoma Uteri.
Publication date: Dec 01, 2019 The incidence of melanoma is increasing worldwide. It is known ... -
Fertility drugs and cutaneous melanoma risk: a French prospective cohort study.
Publication date: Nov 18, 2019 Cutaneous melanoma has been suspected to be influenced by female ... -
The successful use of pembrolizumab in a renal transplant recipient with metastatic melanoma.
Publication date: Nov 18, 2019 We report a case in which a renal transplant recipient ... -
Long Noncoding RNA PVT1 Silencing Prevents the Development of Uveal Melanoma by Impairing MicroRNA-17-3p-Dependent MDM2 Upregulation.
Publication date: Nov 01, 2019 Uveal melanoma is a common primary intraocular malignancy accompanied by ... -
Oncolytic Newcastle disease virus expressing a checkpoint inhibitor as a radioenhancing agent for murine melanoma.
Publication date: Nov 01, 2019 Monoclonal antibodies (mAbs) targeting negative regulators, or checkpoint molecules (e.g. ... -
Conjunctival Melanoma in Childhood and Adolescence: A Systematic Review.
Publication date: Oct 01, 2019 Conjunctival melanoma is rare in adults and rarer in children. ... -
Food and Beverage Consumption and Melanoma Risk: A Population-Based Case-Control Study in Northern Italy.
Publication date: Sep 12, 2019 It has been suggested that diet may influence the risk ... -
THE ROLE OF ESTROGENS AND ESTROGEN RECEPTORS IN MELANOMA DEVELOPMENT AND PROGRESSION.
Publication date: Jun 01, 2019 Melanoma has a significant mortality and its growing incidence is ... -
Factors Influencing the Efficacy of Anti-PD-1 Therapy in Chinese Patients with Advanced Melanoma.
Publication date: May 22, 2019 Anti-PD-1 antibody improves the survival of patients with advanced melanoma. ... -
TRPM1 Autoantibodies in Melanoma Patients Without Self-Reported Visual Symptoms.
Publication date: May 01, 2019 Melanoma-associated retinopathy (MAR) is a paraneoplastic syndrome associated with cutaneous ... -
Assessing recall of personal sun exposure by integrating UV dosimeter and self-reported data with a network flow framework.
Publication date: Mar 29, 2019 Melanoma survivors often do not engage in adequate sun protection, ... -
Combination of radiotherapy and immunotherapy for brain metastases: A systematic review and meta-analysis.
Publication date: Dec 01, 2019 Radiotherapy (RT) represents a mainstay in the treatment of brain ...