Melanoma

This magazine is directed toward patients with Melanoma, their families, care givers, physicians and researchers. The content is gathered, validated, categorized, and supplied using a novel big data cyberinfrastructure technology that continually learns about Melanoma.

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Melanoma Literature

Phase IB/II Trial of Lenvatinib Plus Pembrolizumab in Patients With Advanced Renal Cell Carcinoma, Endometrial Cancer, and Other Selected Advanced Solid Tumors.
January 22, 2020January 22, 2020
Publication date: Jan 21, 2020 Modulation of vascular endothelial growth factor-mediated immune suppression via angiogenesis ...
Melanoma Literature

Role of fucosyltransferase IV in the migration and invasion of human melanoma cells.
January 22, 2020January 22, 2020
Publication date: Jan 21, 2020 Malignant melanoma is one of the most aggressive human tumor ...
Melanoma Literature

Genome organization in proximity to the BAP1 locus appears to play a pivotal role in a variety of cancers.
January 21, 2020
Publication date: Jan 19, 2020 Cancer studies primarily focus on the characterization of the key ...
Melanoma Literature

Association of IRF4 SNP rs12203592 with melanoma-specific survival.
January 21, 2020January 21, 2020
Publication date: Jan 20, 2020 We have previously shown that the functional melanoma risk variant ...
Melanoma Literature

Highly potent intradermal vaccination by an array of dissolving microneedle polypeptide cocktails for cancer immunotherapy.
January 21, 2020
Publication date: Jan 20, 2020 Despite recent advances in cancer therapy using vaccines, the efficacy ...
Melanoma Literature

Melanoma – time to fast or time to feast? An interplay between PPARs, metabolism and immunity.
January 21, 2020January 21, 2020
Publication date: Jan 20, 2020 Development and progression of melanoma can be accelerated by intensification ...
Melanoma Literature

Use of Completion Lymph Node Dissection for Sentinel Lymph Node Positive Melanoma.
January 20, 2020
Publication date: Jan 16, 2020 For patients with sentinel node positive melanoma (SNPM), randomized trials, ...
Melanoma Literature

Parent and child perspectives on family interactions related to melanoma risk and prevention after CDKN2A/p16 testing of minor children.
January 20, 2020
Publication date: Jan 18, 2020 Predispositional genetic testing of children for adult-onset health risks is ...
Melanoma Literature

Genetic variants in the folate metabolic pathway genes predict melanoma-specific survival.
January 20, 2020January 20, 2020
Publication date: Jan 18, 2020 Folate metabolism plays an important role in DNA methylation and ...
Melanoma Literature

Immunohistochemistry Utilization in the Diagnosis of Melanoma.
January 20, 2020January 20, 2020
Publication date: Jan 18, 2020 The use of immunohistochemical (IHC) stains in dermatopathology is commonplace, ...
Melanoma Literature

Anti-Metastatic Effects on Melanoma via Intravenous Administration of Anti-NF-κB siRNA Complexed with Functional Peptide-Modified Nano-Micelles.
January 19, 2020January 19, 2020
Publication date: Jan 15, 2020 Controlling metastasis is an important strategy in cancer treatment. Nanotechnology ...
Melanoma Literature

Metformin as Potential Therapy for High-Grade Glioma.
January 19, 2020January 19, 2020
Publication date: Jan 15, 2020 Metformin (MET), 1,1-dimethylbiguanide hydrochloride, is a biguanide drug used as ...
Melanoma Literature

Melatonin-Induced Cytoskeleton Reorganization Leads to Inhibition of Melanoma Cancer Cell Proliferation.
January 19, 2020January 19, 2020
Publication date: Jan 15, 2020 Neuroindole melatonin, a hormone synthesized during the night mainly-but not ...
Melanoma Literature

Possibilities of Improving the Clinical Value of Immune Checkpoint Inhibitor Therapies in Cancer Care by Optimizing Patient Selection.
January 19, 2020January 19, 2020
Publication date: Jan 15, 2020 Immune checkpoint inhibitor (ICI) therapies have become the most important ...
Melanoma Literature

Knockdown of circ_0084043 suppresses the development of human melanoma cells through miR-429/tribbles homolog 2 axis and Wnt/β-catenin pathway.
January 19, 2020January 19, 2020
Publication date: Jan 15, 2020 Circular RNAs (circRNAs) have been emerged as novel regulators in ...
Melanoma Literature

High expression of ID1 in monocytes is strongly associated with phenotypic and functional MDSC markers in advanced melanoma.
January 19, 2020January 19, 2020
Publication date: Jan 17, 2020 The efficacy of immunotherapies for malignant melanoma is severely hampered ...
Melanoma Literature

Improved melanoma outcomes and survival in patients monitored by total body photography: A natural experiment.
January 19, 2020
Publication date: Jan 17, 2020 Total body photography (TBP) facilitates early melanoma detection, but long-term ...
Melanoma Literature

Direct comparison study between droplet digital PCR and a combination of allele-specific PCR, asymmetric rapid PCR and melting curve analysis for the detection of BRAF V600E mutation in plasma from melanoma patients.
January 19, 2020January 19, 2020
Publication date: Jan 18, 2020 Background In metastatic melanoma, 40%-50% of patients harbor a BRAF ...
Melanoma Literature

Immunological analyses reveal an immune subtype of uveal melanoma with a poor prognosis.
January 19, 2020January 19, 2020
Publication date: Jan 18, 2020 Uveal melanoma is an aggressive intraocular malignancy that often exhibits ...
Melanoma Literature

CNP mediated selective toxicity on melanoma cells is accompanied by mitochondrial dysfunction.
January 18, 2020January 18, 2020
Publication date: Sep 10, 2019 Cerium (Ce) oxide nanoparticles (CNP; nanoceria) are reported to have ...
Melanoma Literature

Accuracy of The Cancer Genome Atlas Classification vs American Joint Committee on Cancer Classification for Prediction of Metastasis in Patients With Uveal Melanoma.
January 18, 2020
Publication date: Jan 16, 2020 The Cancer Genome Atlas (TCGA) classification is a newly emerging ...