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June 21, 2022June 21, 2022

Moving the Dial Toward Equity in Parkinson's Disease Clinical Research: a Review of Current Literature and Future Directions in Diversifying PD Clinical Trial Participation.

Publication date: Jun 17, 2022 Parkinson’s disease (PD), the second most common neurodegenerative disease, has a worldwide prevalence projected at 12 million by 2040. While PD has been extensively researched, ... Read more

June 17, 2022June 17, 2022

Amped-PD: Amplifying Physical Activity Through Music in Parkinson Disease

Parkinson's Disease News

Publication date: Jun 16, 2022 Regular, habitual exercise is a critical component of the long-term management of Parkinson disease (PD). However, PD-specific motor (e. g. slow and diminished movements, variable ... Read more

June 4, 2022June 4, 2022

Dosing Begins in Phase 2b Study of Oral BIIB122/DNL151

Parkinson's Disease News

Publication date: Jun 03, 2022 While LRRK2 mutations are seen in both familial and sporadic Parkinson’s disease, patients without these mutations also show higher levels of active LRRK2 protein. A ... Read more

June 2, 2022June 2, 2022

Biogen, Denali begin Phase IIb trial of Parkinson's disease therapy

Parkinson's Disease News

Publication date: Jun 02, 2022 Biogen and Denali Therapeutics have initiated dosing in the international Phase IIb LUMA clinical trial of BIIB122 (DNL151) in subjects with early-stage Parkinsons disease. Denali ... Read more

June 2, 2022June 2, 2022

Combination intravitreous melphalan and bevacizumb for cutaneous metastatic melanoma to the vitreous and retina.

Melanoma Literature

Publication date: Jun 01, 2022 Cutaneous melanoma metastatic to the vitreous/retina is rare but increasingly common. Due to the potential of recurrent disease with current treatment options and the propensity ... Read more

June 2, 2022June 2, 2022

UHPLC-MS/MS-GNPS based phytochemical investigation of Equisetum arvense L. And evaluation of cytotoxicity against human melanoma and ovarian cancer cells.

Melanoma Literature

Publication date: Jun 01, 2022 Equisetum arvense L. is widely used as a traditional medicine for the management of inflammation and cancer. In the present study, phyto-chemical analysis of E. ... Read more

May 27, 2022May 27, 2022

Z-DNA Triggering Drug Kills Immunotherapy Resistant Melanoma by Mimicking Flu

Melanoma News

Publication date: May 26, 2022 Co-senior author of the paper, Balachandran, said, -We know that influenza viruses trigger very potent immune responses in infected cells. That way, the body’s own ... Read more

May 27, 2022May 27, 2022

Desmoplastic melanoma responds to PD-1 blockade immunotherapy

Melanoma News

Publication date: May 27, 2022 Its a cancer in which local relapse is common, so the standard of care is surgery with wide excision margins followed by radiation therapy. SWOG ... Read more

May 24, 2022May 24, 2022

Unmet needs of women with Parkinson's disease: Gaps and controversies

Parkinson's Disease Media

Publication date: May 23, 2022 Dr. Sarah Lidstone interviews Dr. Indu Subramanian about her recent paper, “Unmet needs of women with Parkinson’s disease: Gaps and Controversies,” in Movement Disorders. Read ... Read more

May 24, 2022May 24, 2022

A Decade of Transformation in Melanoma Treatments

Melanoma News

Publication date: May 24, 2022 The trials that led to the approval showed an overall response rate (ORR) of just 10. 9% in patients with previously treated advanced melanoma, but ... Read more