Parkinson’s Disease – Ingentium News Magazine

This magazine is directed toward patients with Parkinson’s Disease, their families, care givers, physicians and researchers. The content is gathered, validated, categorized, and supplied using a novel big data cyberinfrastructure technology that continually learns about Parkinson’s Disease.

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Parkinson's Disease News

A Study to Assess the Safety and Effectiveness of Pridopidine Compared to Placebo in the Treatment of Levodopa-Induced Dyskinesia in Patients With Parkinson’s Disease
April 23, 2019April 23, 2019
Publication date: Apr 22, 2019 This is a multicenter, randomized, double-blind, placebo-controlled, three-arm parallel group ...
Parkinson's Disease News

Piano Training, Caregivers, and Parkinson’s Disease
April 23, 2019April 23, 2019
Publication date: Apr 22, 2019 The purpose of this study is to investigate the impact ...
Parkinson's Disease Media

‘Unlocking The Brain’ – Parkinson’s Disease – Dr Richard Gordon
April 23, 2019April 23, 2019
Publication date: Apr 23, 2019 Dr Ricahrd Gordon presented on April 4, 2019, on the ...
Parkinson's Disease Literature

α-synuclein oligomers enhance astrocyte-induced synapse formation through TGF-β1 signaling in a Parkinson’s disease model.
April 23, 2019
Publication date: Apr 22, 2019 Parkinson’s disease (PD) is characterized by selective death of dopaminergic ...
Parkinson's Disease Literature

Inhibition of MEK5 suppresses TDP-43 toxicity via the mTOR-independent activation of the autophagy-lysosome pathway.
April 22, 2019
Publication date: Apr 17, 2019 The most prominent hallmarks of many neurodegenerative diseases are the ...
Parkinson's Disease Literature

Phosphorylated NUB1 distinguishes α-synuclein in Lewy bodies from that in glial cytoplasmic inclusions in multiple system atrophy.
April 22, 2019
Publication date: Apr 21, 2019 Posttranslational modifications by phosphorylation, ubiquitination, neddylation, and other pathways have ...
Parkinson's Disease Literature

Selective vulnerability in α-synucleinopathies.
April 22, 2019April 22, 2019
Publication date: Apr 20, 2019 Parkinson’s disease, dementia with Lewy bodies, and multiple system atrophy ...
Parkinson's Disease Literature

Long non-coding RNA-p21 regulates MPP-induced neuronal injury by targeting miR-625 and derepressing TRPM2 in SH-SY5Y cells.
April 21, 2019
Publication date: Apr 17, 2019 Parkinson’s disease (PD), the second most prevalent age-related neurodegenerative disease, ...
Parkinson's Disease Literature

Therapeutic Efficacy of Glial Cell-Derived Neurotrophic Factor Loaded Collagen Scaffolds in ex vivo organotypic brain slice Parkinson’s Disease Models.
April 21, 2019
Publication date: Apr 17, 2019 Glial cell line-derived neurotrophic factor (GDNF) is a potent trophic ...
Parkinson's Disease Literature

Regulation of neuronal microtubule dynamics by tau: Implications for tauopathies.
April 21, 2019April 21, 2019
Publication date: Apr 17, 2019 In specialized cell types such as neurons, microtubules maintain the ...
Parkinson's Disease Literature

Repetitive transcranial magnetic stimulation protects mice against 6-OHDA-induced Parkinson’s disease symptoms by regulating brain amyloid β level.
April 21, 2019April 21, 2019
Publication date: Apr 19, 2019 Repetitive transcranial magnetic stimulation (rTMS) is a technique protecting neurons ...
Parkinson's Disease Literature

In vitro models of synucleinopathies: informing on molecular mechanisms and protective strategies.
April 21, 2019
Publication date: Apr 20, 2019 Alpha-synuclein (aSyn) is a central player in Parkinson’s disease (PD) ...
Parkinson's Disease News

SMARTfit Training for Parkinson’s Disease
April 20, 2019April 20, 2019
Publication date: Apr 19, 2019 This pilot study aims to investigate the effects of 8-week ...
Parkinson's Disease News

Improving Walking Ability in Parkinson Disease
April 20, 2019April 20, 2019
Publication date: Apr 19, 2019 Gait impairments of patients with Parkinson’s disease (PD) limit the ...
Parkinson's Disease News

Involvement of cortical dysfunction in frequent falls in patients with Parkinson’s disease – Otomune H, Mihara M, Hattori N, Fujimoto H, Kajiyama Y, Konaka K, Mitani Y, Watanabe Y, Mochizuki H.
April 20, 2019April 20, 2019
Publication date: Apr 19, 2019 • phrase search: “breast cancer” • AND is implied so ...
Parkinson's Disease News

Volatile Biomarkers Could Lead to Early Detection of Parkinson Disease
April 20, 2019April 20, 2019
Publication date: Apr 20, 2019 Volatile biomarkers of Parkinson disease (PD) could be identified through ...
Parkinson's Disease Literature

Association Between Subglottic Pressure and Pulmonary Function in Individuals With Parkinson’s Disease.
April 20, 2019
Publication date: Apr 15, 2019 In individuals with Parkinson’s disease (PD), pulmonary complication such as ...
Parkinson's Disease Literature

Genetic silencing of striatal CaV1.3 prevents and ameliorates levodopa dyskinesia.
April 20, 2019
Publication date: Apr 19, 2019 Levodopa-induced dyskinesias are an often debilitating side effect of levodopa ...
Parkinson's Disease Literature

Felodipine induces autophagy in mouse brains with pharmacokinetics amenable to repurposing.
April 20, 2019April 20, 2019
Publication date: Apr 18, 2019 Neurodegenerative diseases like Alzheimer’s disease, Parkinson’s disease and Huntington’s disease ...
Parkinson's Disease News

Blood pressure drug shows promise for treating Parkinson’s and dementia in animal study
April 19, 2019April 19, 2019
Publication date: Apr 19, 2019 A prescribed drug to treat high blood pressure has shown ...
Parkinson's Disease News

High-intensity exercise shown to slow progression of Parkinson’s
April 19, 2019April 19, 2019
Publication date: Apr 19, 2019 The gloves come on during Emily Moncheski’s specialized fitness classes. ...