Parkinson’s Disease – Ingentium News Magazine

This magazine is directed toward patients with Parkinson’s Disease, their families, care givers, physicians and researchers. The content is gathered, validated, categorized, and supplied using a novel big data cyberinfrastructure technology that continually learns about Parkinson’s Disease.

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Parkinson's Disease Literature

A breakdown in microglial metabolic reprogramming causes internalization dysfunction of α-synuclein in a mouse model of Parkinson's disease.
May 24, 2022May 24, 2022
Publication date: May 22, 2022 The α-synuclein released by neurons activates microglia, which then engulfs ...
Parkinson's Disease Literature

Polygenic resilience modulates the penetrance of Parkinson's disease genetic risk factors.
May 24, 2022May 24, 2022
Publication date: May 22, 2022 The aim of the current study is to understand why ...
Parkinson's Disease Literature

Association of Catechol-O-Methyltransferase Gene rs4680 Polymorphism and Levodopa Induced Dyskinesia in Parkinson's Disease: A Meta-Analysis and Systematic Review.
May 24, 2022May 24, 2022
Publication date: May 22, 2022 Long-term levodopa therapy for Parkinson’s disease (PD) can cause levodopa ...
Parkinson's Disease Literature

Imaging and genetics in Parkinson's disease: assessment of the GBA1 mutation.
May 24, 2022May 24, 2022
Publication date: May 23, 2022 Several genetic variants are associated with an increased risk for ...
Parkinson's Disease Literature

Effect of deep brain stimulation on freezing of gait in patients with Parkinson's disease: a systematic review.
May 24, 2022May 24, 2022
Publication date: May 23, 2022 Freezing of gait (FOG) is a disabling gait disorder in ...
Parkinson's Disease Literature

A Pilot Study of Telehealth Mindfulness-Based Cognitive Therapy for Depression in Parkinson's Disease.
May 24, 2022May 24, 2022
Publication date: May 23, 2022 Introduction: Parkinson’s disease (PD) is characterized by high-rates of depression ...
Parkinson's Disease Literature

Enhanced taste recognition following subacute treatment with the dopamine D2/D3 receptor agonist pramipexole in healthy volunteers.
May 24, 2022May 24, 2022
Publication date: May 23, 2022 Patients with Parkinson’s disease (PD) show impaired performance in taste ...
Parkinson's Disease Literature

A Kinematic Data-Driven Approach to Differentiate Involuntary Choreic Movements in Individuals with Neurological Conditions.
May 24, 2022May 24, 2022
Publication date: May 23, 2022 The ability to differentiate similar choreic involuntary movements could lay ...
Parkinson's Disease Literature

Modified viral-genetic mapping reveals local and global connectivity relationships of ventral tegmental area dopamine cells.
May 24, 2022May 24, 2022
Publication date: May 23, 2022 Dopamine cells in the ventral tegmental area (VTA) are critical ...
Parkinson's Disease Literature

Levodopa-induced dyskinesia is preceded by increased levels of anxiety and motor impairment in Parkinson's disease patients.
May 24, 2022May 24, 2022
Publication date: May 23, 2022 Dopamine replacement therapy with levodopa is the gold standard treatment ...
Parkinson's Disease Literature

α-Synuclein fibrils explore actin mediated macropinocytosis for cellular entry into model neuroblastoma neurons.
May 24, 2022May 24, 2022
Publication date: May 23, 2022 Alpha-Synuclein (α-Syn), an intrinsically disordered protein (IDP), is associated with ...
Parkinson's Disease Literature

Systematic literature review of the epidemiology of glyphosate and neurological outcomes.
May 24, 2022May 24, 2022
Publication date: May 23, 2022 Human health risk assessments of glyphosate have focused on animal ...
Parkinson's Disease Literature

Clinical Manifestations of Early-Onset Dementia With Lewy Bodies Compared With Late-Onset Dementia With Lewy Bodies and Early-Onset Alzheimer Disease.
May 24, 2022May 24, 2022
Publication date: May 23, 2022 Early-onset dementia, presenting in individuals younger than 65 years, is ...
Parkinson's Disease Literature

Pretreatment with Perlecan-Conjugated Laminin-E8 Fragment Enhances Maturation of Grafted Dopaminergic Progenitors in Parkinson's Disease Model.
May 24, 2022May 24, 2022
Publication date: May 23, 2022 The therapeutic effect of a cell replacement therapy for Parkinson’s ...
Parkinson's Disease Literature

Diagnostic accuracy of noun- and verb-naming tasks in detecting cognitive impairment in Parkinson's disease.
May 24, 2022May 24, 2022
Publication date: May 23, 2022 In Parkinson’s disease (PD), verb-naming tasks have been proposed as ...
Parkinson's Disease Literature

A dystonia mouse model with motor and sequencing deficits paralleling human disease.
May 24, 2022May 24, 2022
Publication date: May 24, 2022 The dystonias are a group of movement disorders characterized by ...
Parkinson's Disease News

Combining Aerobic Exercise and Virtual Reality for Cognitive-motor Rehabilitation in PD
May 24, 2022May 24, 2022
Publication date: May 23, 2022 This project will provide preliminary data on the feasibility and ...
Parkinson's Disease News

MUSCLE – Nordic Walking in MUltiple SCLErosis
May 24, 2022May 24, 2022
Publication date: May 23, 2022 The aim of the study is to analyze the effects ...
Parkinson's Disease News

Towards the Validation of a New Blood Biomarker for the Early Diagnosis of Parkinson's Disease
May 24, 2022May 24, 2022
Publication date: May 23, 2022 We have recently discovered a metabolic biomarker which predicts Parkinson’s ...
Parkinson's Disease News

Parkinson's disease: Cerevance outlines Phase II/III trial planned for Q1 2023
May 24, 2022May 24, 2022
Publication date: May 24, 2022 The number of clinical trial initiations in Parkinsons disease steadily ...
Parkinson's Disease News

Super-strength MRI identifies neurodegeneration in Parkinson's disease
May 24, 2022May 24, 2022
Publication date: May 24, 2022 This MRI scanner enabled the researchers to examine the locus ...