Prodromal Parkinson disease subtypes – key to understanding heterogeneity.
Publication date: Apr 20, 2021 In Parkinson disease (PD), pathological processes and neurodegeneration begin long ...
Parkinson’s Disease
This magazine is directed toward patients with Parkinson’s Disease, their families, care givers, physicians and researchers. The content is gathered, validated, categorized, and supplied using a novel big data cyberinfrastructure technology that continually learns about Parkinson’s Disease.
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Impaired cerebral microcirculation in isolated REM sleep behaviour disorder.
Publication date: Apr 20, 2021 During the prodromal period of Parkinson’s disease and other α-synucleinopathy-related ... -
Conveyance of cortical pacing for parkinsonian tremor-like hyperkinetic behavior by subthalamic dysrhythmia.
Publication date: Apr 20, 2021 Parkinson’s disease is characterized by both hypokinetic and hyperkinetic symptoms. ... -
Short-Term High-Intensity Treadmill Exercise Promotes Ceramide-Dependent Extracellular Vesicle Secretion in the Central Nervous System of Mice.
Publication date: Apr 21, 2021 BACKGROUND A lack of physical exercise, a critical aspect of ... -
Gastrointestinal dysfunction in Parkinson's disease: molecular pathology and implications of gut microbiome, probiotics, and fecal microbiota transplantation.
Publication date: Apr 21, 2021 Gastrointestinal symptoms and gut dysbiosis may occur before the onset ... -
Alpha-Synuclein Oligomers and Neurofilament Light Chain Predict Phenoconversion of Pure Autonomic Failure.
Publication date: Apr 21, 2021 To explore the role of alpha-synuclein (αSyn) oligomers and neurofilament ... -
Emerging urinary alpha-synuclein and miRNA biomarkers in Parkinson's disease.
Publication date: Apr 21, 2021 Parkinson’s disease (PD) is one of the most common neurodegenerative ... -
MiR-30a-5p Regulates GLT-1 Function via a PKCα-Mediated Ubiquitin Degradation Pathway in a Mouse Model of Parkinson's Disease.
Publication date: Apr 21, 2021 Glutamate excitotoxicity is caused by dysfunctional glutamate transporters and plays ... -
Regulating inflammation associated Ferroptosis-a treatment strategy for Parkinson disease.
Publication date: Apr 19, 2021 Ferroptosis plays a critical regulatory role for a new kind ... -
Association of Stress-Health Factors among Parkinson's Disease Patient/Caregiving-Partner Dyads.
Publication date: Apr 19, 2021 Few studies have explored the shared effects of Parkinson’s disease ... -
Genotype-driven therapeutic developments in Parkinson's disease.
Publication date: Apr 19, 2021 Remarkable advances have been reached in the understanding of the ... -
The potential role of miR-124-3p in tumorigenesis and other related diseases.
Publication date: Apr 20, 2021 MicroRNAs (miRNAs) are a class of single-stranded noncoding and endogenous ... -
Gut microbiota-derived vitamins – underrated powers of a multipotent ally in psychiatric health and disease.
Publication date: Apr 20, 2021 Despite the well-established roles of B-vitamins and their deficiencies in ... -
Superoxide Dismutase 1 in Health and Disease: How a Frontline Antioxidant Becomes Neurotoxic.
Publication date: Apr 19, 2021 Cu/Zn superoxide dismutase (SOD1) is a frontline antioxidant enzyme catalysing ... -
Magnetic Targeting of Human Olfactory Mucosa Stem Cells Following Intranasal Administration: a Novel Approach to Parkinson's Disease Treatment.
Publication date: Apr 15, 2021 Among the various therapeutic procedures used for improving PD, stem ... -
Pre-stimulus low-alpha frontal networks are associated with pareidolias in Parkinson's disease.
Publication date: Apr 15, 2021 Background: Pareidolias are visual phenomena wherein ambiguous, abstract forms or ... -
Clinical implications for dopaminergic and functional neuroimage research in cognitive symptoms of Parkinson's disease.
Publication date: Apr 15, 2021 Evidence from dopaminergic image and cerebral blood flow/metabolism images have ... -
New phosphosite-specific antibodies to unravel the role of GRK phosphorylation in dopamine D receptor regulation and signaling.
Publication date: Apr 15, 2021 The dopamine D receptor (DR) is the target of drugs ... -
Nanoemulsion Improves the Neuroprotective Effects of Curcumin in an Experimental Model of Parkinson's Disease.
Publication date: Apr 16, 2021 Parkinson’s disease (PD) is a neurodegenerative disorder characterized by motor ... -
Meta-Analysis of Cognition in Parkinson's Disease Mild Cognitive Impairment and Dementia Progression.
Publication date: Apr 16, 2021 Mild cognitive changes, including executive dysfunction, are seen in Parkinson’s ... -
Multi-objective data-driven optimization for improving deep brain stimulation in Parkinson's disease.
Publication date: Apr 16, 2021 Deep brain stimulation (DBS) is an effective treatment for Parkinson’s ...