Parkinson’s Disease
Parkinson’s disease is a progressive neurological disorder that primarily affects movement. It is named after Dr. James Parkinson, the physician who first described the condition in 1817. Parkinson’s disease develops as a result of the degeneration and loss of dopamine-producing cells in a region of the brain called the substantia nigra.
The exact cause of Parkinson’s disease is still unknown, but it is believed to involve a combination of genetic and environmental factors. There is currently no cure for Parkinson’s disease, but various treatment approaches aim to manage symptoms and improve quality of life. Medications, such as levodopa and dopamine agonists, can help replenish dopamine levels or mimic its effects. Physical therapy, occupational therapy, and speech therapy can assist with mobility, daily activities, and communication. In some cases, deep brain stimulation (DBS) surgery may be recommended to alleviate symptoms.
This magazine contains content which is gathered, validated, categorized, and supplied using a novel big data cyberinfrastructure technology that continually learns about Parkinson’s Disease.
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Publication date: Dec 03, 2025 Parkinson’s disease (PD) is a progressive neurodegenerative disease thought to ...
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Primary Brain Calcification: An International Consensus on Nomenclature, Diagnosis, Evaluation, and Management.
Publication date: Dec 04, 2025 Our understanding of primary brain calcification (PBC) has accelerated with ... -
Divergence of cortical neurophysiology across different neurodegenerative disorders compared to healthy ageing.
Publication date: Dec 03, 2025 Neurodegenerative diseases involve disruption of healthy brain network communication occurring ... -
The effect of beta-neurofeedback on beta-bursts in Parkinson’s disease patients as evidenced through deep brain recordings.
Publication date: Dec 04, 2025 Increased beta-oscillations (13-35 Hz) in the basal ganglia have been ... -
Brain Imaging Changes Following Deep Brain Stimulation Patients with Parkinson’s Disease: A Literature Review.
Publication date: Dec 04, 2025 Parkinson’s Disease (PD) is a progressive neurodegenerative disorder primarily characterized ... -
Delayed Disease Onset Report in UK Biobank: Implications for Prodromal Studies in Parkinson’s Disease.
Publication date: Dec 04, 2025 UK Biobank (UKBB) provides extensive genetic, imaging, and health data ... -
Convolutional neural networks-based early Parkinson’s disease classification using cycling data from a steerable indoor bicycle.
Publication date: Dec 05, 2025 Parkinson’s disease (PD) is a neurodegenerative disorder that leads to ... -
The Vagus Connection: Exploring the Neurobiology of Brain-Gut Communication.
Publication date: Dec 05, 2025 The vagus nerve (cranial nerve X) originates in the brainstem, ... -
Loss of Parkinson Disease Protein 7 (PARK7) upregulates ROS and cell migration and is associated with recurrent pregnancy loss.
Publication date: Dec 05, 2025 Open Access PDF Concepts Keywords Park7 Cytoskeleton Parkinson Decidualization Pregnancy ... -
Orally Administered Bacillus licheniformis F0726 Attenuates MPTP/P-Induced Neurodegeneration by Modulating Gut Microbiota and Suppressing Inflammatory Responses.
Publication date: Dec 05, 2025 Extensive studies have shown that Parkinson’s disease (PD) is associated ... -
Longitudinal assessment of DNA repair signature trajectory in prodromal versus established Parkinson’s disease.
Publication date: Dec 05, 2025 Parkinson’s disease (PD) is a progressive neurodegenerative disorder. DNA repair ... -
Differential microglial responses to structurally distinct alpha-synuclein polymorphs.
Publication date: Dec 05, 2025 Synucleinopathies are age-related neurological disorders which include dementia with Lewy ... -
Language Competence in Parkinson’s Disease: A Systematic Review of 20 Years of Research.
Publication date: Dec 05, 2025 Parkinson’s disease (PD) is the second most common neurodegenerative condition ... -
Supplementation with short-chain fatty acids and a prebiotic improves clinical outcome in Parkinson’s disease: a randomized double-blind prospective study.
Publication date: Dec 05, 2025 Parkinson’s disease is associated with a dysbiotic, proinflammatory gut microbiome, ... -
Preserved white matter integrity is a promising indicator of cognitive resilience in Parkinson’s disease.
Publication date: Dec 05, 2025 Open Access PDF Concepts Keywords Disease Cognitive function Parkinson Cognitive ... -
Preoperative treatment with bisphosphonates does not change the thermal response of focused ultrasound thalamotomy.
Publication date: Dec 05, 2025 Introduction Skull density ratio (SDR) is an important criterion for ... -
Trends and Future Projections of Neurological Disorder Burden in Europe,1990-2021: Latest Insights from the GBD 2021 Study.
Publication date: Dec 05, 2025 The systematic assessment of the burden of common neurological disorders ... -
Clinical, Biological, and Functional Connectivity Profile of Patients With De Novo Parkinson Disease Who Are APOE ε4 Carriers.
Publication date: Jan 13, 2026 Growing evidence suggests that the APOE ε4 allele, a genetic ... -
International consensus for the assessment of social cognition in neurocognitive disorders: framework definition and clinical recommendations of the SIGNATURE initiative.
Publication date: Dec 06, 2025 Socio-cognitive assessment in neurocognitive disorders (NCDs) is rare in clinical ... -
Dancing through time: Cognitive changes over six years of community dance in Parkinson’s disease.
Publication date: Dec 05, 2025 BackgroundParkinson’s disease (PD) is the most common neurodegenerative disorder after ... -
Olfactory-to-Entorhinal Network Dysrhythmias Drive Parkinson’s Cognitive Impairment Through Frequency-Specific Oscillatory Decoupling.
Publication date: Dec 05, 2025 Parkinson’s disease (PD)-associated cognitive decline is heralded by olfactory dysfunction, ...